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• SciCrunch
• 16 years ago - by Anonymous

Established in 1980, the Life Extension Foundation is a nonprofit organization, whose long-range goal is to radically extend the healthy human lifespan by discovering scientific methods to control aging and eradicate disease. The largest organization of its kind in the world, the Life Extension Foundation has always been at the forefront of discovering new scientific breakthroughs for use in developing novel disease prevention and treatment protocols to improve the quality and length of human life. Through its private funding of research programs aimed at identifying and developing new therapies to slow and even reverse the aging process, the Life Extension Foundation seeks to reduce, and ultimately eliminate, such age-related killers as heart disease, stroke, cancer and Alzheimer''s disease. Long-time members are keenly aware of the scientific research that Life Extension Foundation funds to develop validated methods to slow and reverse the aging process. Less known is Life Extension''s multi-prong program to develop safer and more effective cancer therapies. One reason we focus so heavily on cancer research is that this dreaded disease represents a roadblock in our ability to develop effective means to combat aging.

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• SciCrunch
• 16 years ago - by Anonymous

A robust tool for microRNA target prediction with systematic identification of negative examples.

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• SciCrunch
• 13 years ago - by Anonymous

An online tool to identify homologous miRNA genes. This tool can search for new miRNA candidates by requiring structural similarity and sequence conservations between new candidates and experimentally identified miRNAs. Simply Input your sequence and parameters.

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• SciCrunch
• 16 years ago - by Anonymous

Leading contract research and manufacturing services company in the area of drug discovery and development.

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• SciCrunch
• 16 years ago - by Anonymous

Common Knowledge: I''m John Wilbanks. I run the Science Commons project at Creative Commons.

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• SciCrunch
• 16 years ago - by Anonymous

Not yet vetted by NIF curator

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• SciCrunch
• 16 years ago - by Anonymous

A company which provides nonhuman primate products and bio-research services for the global scientific community. They provide serum, plasma, whole blood, and tissue samples from primates such as the Cynomolgus macaque, the Rhesus macaque, and the African Green. Products based on others species are available upon request.

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• SciCrunch
• 16 years ago - by Anonymous

Not yet vetted by NIF curator

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• SciCrunch
• 16 years ago - by Anonymous

Not yet vetted by NIF curator

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• SciCrunch
• 16 years ago - by Anonymous

MethCGI is a tool to predict the methylation status of CpG islands in the human brain, developed on the data from human brain DNA using support vector machine (SVM).

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• SciCrunch
• 16 years ago - by Anonymous

Commercial medical device company focused on developing minimally disruptive surgical products and procedures for spine.

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• SciCrunch
• 16 years ago - by Anonymous

Not for profit, precompetitive alliance of life science companies, vendors, publishers, and academic groups that aims to lower barriers to innovation by improving interoperability of R and D business processes.

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• SciCrunch
• 16 years ago - by Anonymous

Dr. Lewis Coriell''s pioneering techniques for characterizing, freezing, and storing cell cultures in liquid nitrogen constitute one of the greatest contributions to modern human research. Today, the Coriell Biobank is regarded as the most diverse collection of cell lines and DNA available to the international research community. In addition to these high-quality biospecimens, Coriell also maintains tissue, plasma, serum, urine, and cerebrospinal fluid. Few organizations have the history of innovations in repository science that have been developed and implemented at Coriell. For nearly 60 years, Coriell has set the standard in biobanking services, including the experimental design, collection, processing, distribution, cryogenic preservation, and information management of human biomaterials used in research. By developing and maintaining biorepositories as national and international resources for the study of human diseases, aging, and neurological disease, Coriell is committed to providing the scientific community with well-characterized, cell cultures and DNA preparations, annotated with rich phenotypic data. The Coriell Biobank has allowed both Coriell scientists, and research investigators around the world, to advance research programs in genetics and cell biology. Since the first repository ����?����������?? a National Institutes of Health collection ����?����������?? was established at Coriell in 1964, hundreds of thousands of cell lines and DNA samples have been distributed to researchers in 64 countries; more than 7,000 peer-reviewed papers have been published citing almost 12,000 biospecimens from the Coriell Biobank. Coriell''s repositories provided support to the Human Genome Project, a worldwide program to map the entire human genome, and to the International HapMap Project, a project providing an efficient tool to identify disease-causing genes. Coriell offers almost 60 years of experience in the banking, cryopreservation, and fail-safe storage of cell lines, DNA, and other biomaterials. The renowned Coriell biobank is ISO9001:2008 certified. Our highly-trained technicians, supported by on-staff scientists with expertise with genomics, provide proficient, individualized care for your biospecimens. From specimen collection, processing, quality control, enterprise level data, and inventory management, through rapid retrieval of specimens and secure shipment, Coriell offers full-service biorepository services.

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• SciCrunch
• 16 years ago - by Anonymous

YeastFunc is a public database for browsing of quantitative S. cerevisiae gene function predictions, gene function linkage predictions, and the evidence behind the predictions, overlayed upon the experimentally verified annotations as taken from the SGD, MGI and Ensembl Gene databases, respectively. Three aspects of gene function predictions are displayed: * First, for a particular gene, users can view all functions ranked by certainty that the corresponding gene-function pair is a true annotation. * Second, for a particular function, users can view all genes ranked by certainty. * The third aspect is functional linkage predictions, displayed alongside the first two aspects as gene-centered and function-centered images, respectively, and editable via Cytoscape. These functional linkage graphs are independently informative, though they are also used as a step in one of the gene function prediction techniques whose certainty scores are displaying on this site, so they can be treated as evidence. Evidence leading to all gene function predictions in the first two aspects as well as all experimentally verified gene function annotation is displayed alongside each of the first two aspects, allowing the user to understand the basis for the certainty score. To get started type a Gene Ontology ID, an SGD ID, an ORF ID, an Ensembl gene id, an Entrez gene id, a Uniprot id, a standard gene name, or a general search term in the text box. The results of your search will appear below the search box. These results are solely Gene Ontology terms and genes for the species that you selected. Click the result that you would like to investigate further. Note the paging toolbar at the bottom of the results list. If you are interested in performing your own analyses upon all prediction scores displayed on this site you may download the file. Of the 15,633,440 scored yeast gene-function pairs, 6,368 genes have scores and 4,877 genes have at least one experimentally verified function.

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• SciCrunch
• 16 years ago - by Anonymous

Not yet vetted by NIF curator

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• SciCrunch
• 16 years ago - by Anonymous

Atlas of gene expression in the developing rhesus macaque brain. This atlas is a free online resource with a unique set of data and tools aimed to create a developmental neuroanatomical framework for exploring the cellular and molecular architecture of the developing postnatal primate brain with direct relevance for human brain development. The atlas includes: * Microarray ** Microdissection: Fine structure transcriptional profiling across postnatal development for fine nuclear subdivisions of the prefrontal cortex, primary visual cortex, hippocampus, amygdala and ventral striatum ** Macrodissection: Gross structure transcriptional profiling across postnatal development for the same structures * ISH: ** Cellular resolution in situ hybridization image data of five major brain regions during postnatal developmental periods for genes clinically important for a variety of human neurodevelopmental disorders, including prefrontal cortex, primary visual cortex, hippocampus, amygdala and ventral striatum. ** Serial analysis of selected genes across the entire adult brain, focusing on cellular marker genes, genes with cortical area specificity and gene families important to neural function. * ISH Anatomic Search: Detailed gene expression search on the ISH data based on expert annotation * Reference Data: Developmental stage-specific reference series, consisting of magnetic resonance imaging (MRI) and Nissl histology to provide a neuroanatomical context for the gene expression data. These data and tools are designed to provide a valuable public resource for researchers and educators to explore neurodevelopment in non-human primates, and a key evolutionary link between other Web-based gene expression atlases for adult and developing mouse and human brain.

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• SciCrunch
• 16 years ago - by Anonymous

Virginia Hughes'' Research Blog

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• SciCrunch
• 16 years ago - by Anonymous

Taiwan Biobank intends to conduct large-scale cohort studies and case-control studies on local diseases. The cohort study will call for 200,000 volunteers, while the case-control study will invite 100,000 patients with the 10 to 15 most common diseases. These studies will enable Taiwan Biobank to identify the disease-causing factors and mechanisms of common diseases to facilitate the development of better treatment and prevention, reduce the cost of medical treatment and make it possible to achieve the goal of improving the island nation’s health.

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• SciCrunch
• 16 years ago - by Anonymous

The Barth Syndrome Foundation, together with our affiliates, is a community of families, physicians, scientists, donors and volunteers around the world. As our mission statement says, we are dedicated to saving lives through education, advances in treatment, and finding a cure for Barth syndrome - a sometimes fatal, oftentimes debilitating genetic disease. Our work includes: * Raising awareness among physicians, scientists, and the general public; * Supporting relevant research through an international grant research program; * Providing a caring and educational community for affected families; and * Hosting a unique information resource. Working together we are making a difference in the lives of children and their families. One day there will be a cure; we hope you will help us make that day come sooner. We are the only world-wide volunteer organization dedicated to saving lives through education, advances in treatment and pursuit of a cure for Barth syndrome (BTHS). We started in 2000, after the first international conference held in Baltimore, MD (USA) where families from around the world met to discuss BTHS. As a result, we made a unanimous decision to work together to find a cure for this multi-system disorder. Our Foundation strives to accelerate progress through collaboration between families and scientists. We encourage family participation in research. Also, we provide several ways to keep up-to-date about advances in science and medicine. Our principal education event is our biennial international scientific, medical and family conference, which brings together the largest number of individuals interested in Barth syndrome. Our Family Services team is continually developing new informational resources in response to the needs of families, individuals, and professionals working with those affected by Barth syndrome.

• Resource
• SciCrunch
• 16 years ago - by Anonymous