Curator Dashboard

BACPAC Resources (a BAC Clones Distribution Center) is the distribution arm of their academic laboratory. They operate on a cost-recovery mechanism in order to make the resources generated in their laboratory available to the academic scientific community. While clones and screening services are widely available, library arrays are primarily available to researchers with a scientific need to analyze most clones in the library. This site contains information on currently available BAC and PAC genomic DNA libraries, BAC Clones, PAC Clones, Fosmid Clones, cDNA collections, high-density colony hybridization filters, and BAC and PAC cloning vectors. Protocols used in our laboratory for the hybridization-based screening of colony filters, purification of BAC and PAC DNA, and end-sequencing methodologies, are also provided. BPRC does not list clones, for two reasons: 1)most clones have not been characterized and lack specific data. 2)all clones are part of libraries and all clones from a particular library share common characteristics. Hence, to find out if BPRC has a particular clone, one needs either use Automatic Clone Validation or else find out if the clone is compatible with the range of clone names for a corresponding clone library. Typically (although not always), clone names are derived from the library name. BPRC uses the NCBI-recommended clone nomenclature & library nomenclature. Most arrayed libraries are available in frozen microtiter dish format to academic and non-academic users provided that there is a scientific need for complete-library access. (for instance to annotate, modify or analyze all BAC clones as part of a genome project). Keywords: BAC, Distribution, SUplier, Laboratory, Scientifc, Clone, Screen, Library, Array, Researcher, Research, PAC, Genomic, DNA, Fosmid, cDNA, Hybridization, Filter, Vector, Cloning, Purification, Microtiter,

• Resource
• SciCrunch
• 16 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 29,2025. Database of functional residues in alpha-helical and beta-barrel membrane proteins. Each protein is identified with its name and source alongwith the Uniprot code. The protein data bank (PDB) codes are also given for available proteins. Different methods and experimental parameters, for example, affinity, dissociation constant, IC50, activity etc. (Details are available at the "Help" page) are given in the database. Further, we have provided the numerical experimental value for each residue (or mutant) in a protein. The experimental data are collected from the literature both by searching the journals as well as with the keyword search at PUBMED. In addition, complete reference is given with journal citation and PMID number. TNFunction is cross-linked with the sequence database, Uniprot, structural database, PDB, and literature database, PubMed. The WWW interface enables users to search data based on various terms with different display options for outputs.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

Ontology and database that links plant anatomy, morphology and growth and development to plant genomics data.Plant Ontology Consortium develops, curates and shares controlled vocabularies (ontologies) that describe plant structures and growth and developmental stages, providing semantic framework for meaningful cross species queries across databases. PO is under active development to expand to encompass terms and annotations from all plants.

• Resource
• SciCrunch
• 16 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 4th,2023. The Tissue Bank began collecting tissue from neurosurgical operations in 1978 and has established an organized repository of characterized tissues that have been collected and maintained in a manner useful for a wide range of studies. Copies of each patient''s consent to donate their tissue for research are maintained in a secure area of the Tissue Bank. Clinical data from each case are logged into a secured computer data base. Tissue received into the Tissue Bank is catalogued and referenced by a consecutive numbering system in order to maintain patients'' confidentiality. We have established a complete histology service including tissue processing, embedding, sectioning and H&E staining for fixed tissues, in addition to creating and staining frozen sections. This facility enables the Tissue Bank to support research needs for fixed samples from animal model experiments, to fulfill requests for paraffin sections from diagnostic samples and to provide frozen sections for histologic review.

• Resource
• SciCrunch
• 16 years ago - by Anonymous

Web service with well defined methods to enable programmatic access to molecular interactions. Standard for computational access to molecular interaction data resources.

• Resource
• SciCrunch
• 14 years ago - by Anonymous

Provides standardized vocabulary of phenotypic abnormalities encountered in human disease. Structured and controlled vocabulary for phenotypic features encountered in human hereditary and other disease. HPO is being developed in collaboration with members of OBO Foundry (Open Biological and Biomedical Ontologies), and logical definitions for HPO terms are being developed using PATO and a number of other ontologies including FMA, GO, ChEBI, and MPATH.

• Resource
• SciCrunch
• 14 years ago - by Anonymous

A tool for automatically scheduling events for rapid-presentation event-related (RPER) fMRI experiments (the schedule is the order and timing of events). Events in RPER are presented closely enough in time that their hemodynamic responses will overlap. This requires that the onset times of the events be jittered in order to remove the overlap from the estimate of the hemodynamic response. RPER is highly resistant to habituation, expectation, and set because the subject does not know when the next stimulus will appear or which stimulus type it will be. RPER is also more efficient than fixed-interval event related (FIER) because more stimuli can be presented within a given scanning interval at the cost of assuming that the overlap in the hemodynamic responses will be linear. In SPM parlance, RPER is referred to as ''stochastic design''. This is a subproject of the Center for Functional Neuroimaging Techniques (http://www.nitrc.org/projects/cfnt/)

• Resource
• SciCrunch
• 15 years ago - by Anonymous

Commercial marketer, distributor and importer of industrial, medical, pharmaceutical and biological research and health innovation products.

• Resource
• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE, documented August 23, 2016. Despite considerable research, fundamental questions about chronic fatigue syndrome (CFS) remain at best partially answered. These questions include its definition, validity, the degree to which it results from genetic versus environmental factors, the nature of the substantial comorbidity observed with other conditions, and the basis of the female preponderance. The overarching aim of this project is to shed light on a number of basic questions about CFS via a large, population-based classical twin study. First, we collected data on ~32,000 adults aged 42-65 years (13,000 complete twin pairs) who are members of the Swedish Twin Registry for persistent fatigue, several overlapping conditions (fibromyalgia, irritable bowel syndrome, tension headache, allergy/eczema, generalized anxiety disorder, and major depression), and a detailed medical history. Second, the medical records of all twins who appeared to have CFS-like illness and a subset of those with CFS-explained were requested reviewed by experts. We have addressed a set of critical questions regarding CFS. First, we estimated the prevalence of CFS and its common comorbidities (fibromyalgia, irritable bowel syndrome, tension headache, allergy/eczema, generalized anxiety disorder, and major depression) in one of the largest samples yet studied. Second, we used a variety of multivariate techniques to derive an empirical typology of prolonged fatigue and to assess how this typology compares to the CFS definition. Third, we quantified the genetic and environmental sources of variation for CFS and its comorbid conditions. Fourth, we examined the influence of gender on these sources of variation. Finally, we analyzed the patterns of comorbidity between CFS and fibromyalgia, irritable bowel syndrome, tension headache, allergy/eczema, generalized anxiety disorder, and major depression using multivariate twin analyses and thereby estimated the extent of overlap between the shared and unique genetic and environmental sources of variation. In a follow-up study of 50 MZ twin pairs stringently discordant for CFS, we are now looking at intrapair differences in gene expression.

• Resource
• SciCrunch
• 15 years ago - by Anonymous

A suite of software that allow users to capture, manage, and analyze effectively data from DNA microarray experiments. The suite of tools consist of four major applications, Microarray Data Manager (MADAM), TIGR_Spotfinder, Microarray Data Analysis System (MIDAS), and Multiexperiment Viewer (MeV), as well as a Minimal Information About a Microarray Experiment (MIAME)-compliant MySQL database, all of which are freely available to the scientific research community.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Software that provides a simple way to do some quality control checks on raw sequence data coming from high throughput sequencing pipelines.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 2nd,2023. TMAD stores raw and processed data from Tissue Microarray experiments along with their corresponding stained tissue images. In addition, TMAD provides methods for data retrieval, grouping of data, analysis and visualization as well as export to standard formats. Researchers at the Stanford University School of Medicine and their collaborators worldwide have constructed many tissue microarrays for use in basic research.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 2nd, 2023. Sequence composition based classifier for metagenomic sequences. It works by capturing signatures of each sequence based on the sequence composition. Each sequence is modeled as a walk in a de Bruijn graph with underlying Markov chain properties. ClaMS captures stationary parameters of the underlying Markov chain as well as structural parameters of the underlying de Bruijn graph to form this signature. In practice, for each sequence to binned, such a signature is computed and matched to similar signatures computed for the training sets. The best match that also qualifies the normalized distance cut-off wins. In the case that the best match does not qualify this cut-off, the sequence remains un-binned.

• Resource
• SciCrunch
• 15 years ago - by Anonymous

A study that aims to find out the most effective medication treatments for Alzheimer's disease symptoms, and to improve the quality of life of people with Alzheimer's disease. The outcomes of these trials will depend not only on randomized treatment assignment but the interactions of the clinical sites with the patients and caregivers. This study's main goals are to generate hypotheses about effectiveness and other issues with antipsychotic use that might undergo future testing.

• Resource
• SciCrunch
• 15 years ago - by Anonymous

Collect, bank, and distribute human tissue and fluid specimens by uniting tissue-based research resources within the OSU Department of Pathology and promoting collaborative research within the OSU Medical Center and related national human research projects. The HTRN is comprised of the Pathology Core Facility (PCF), Tissue Archive Service (TAS), Tissue Procurement Service (TPS), AIDS and Cancer Specimen Resource (ACSR), the Cancer and Leukemia Group B Pathology Coordinating Office (CALGB - PCO), and an Adenoma Polyp Tissue Bank (APTB).

• Resource
• SciCrunch
• 15 years ago - by Anonymous

The Parkinson''s UK Brain Bank is the UK''s largest brain bank dedicated to Parkinson''s. We collect the brain, spinal cord and a sample of cerebrospinal fluid from people with and without Parkinson''s after death. We supply tissue to researchers investigating Parkinson''s in the UK and around the world who are working towards a cure for Parkinson''s. Vital research relies upon the generosity of donors and their families who make the vital gift of brain donation after death. Become a brain donor and help us to find a cure and improve life for everyone affected by Parkinson''s. Just one donated brain can be used in up to 50 different research studies. The Parkinson''s UK Brain Bank is currently supporting more than 100 research projects. And we have more than 6,000 registered potential donors. Our tissue is: * free - unlike other banks, we don''t charge researchers for tissue * high quality - we collect most tissue within 24 hours of death * fast - we aim to supply tissue within 4 weeks * neuropathologically diagnosed - according to the latest criteria And we can: * issue ethical approval for projects that fit our research criteria - saving you time * provide tissue suitable for all modern research techniques - including snap frozen and fixed samples * offer expertise and training to researchers working with human tissue We don''t just supply brain tissue. We also know a lot about our donors, which means we can provide tissue to match your project. Donated tissue come with clinical notes from the healthcare team. And every donor provides details of their symptoms, medical history, lifestyle and medications. This makes our offer of tissue and information unique.

• Resource
• SciCrunch
• 15 years ago - by Anonymous

A university in Germany.

• Organization
• SciCrunch
• 17 years ago - submitted by Stephen Larson

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 28,2023. Platform for Neuroscientists to describe neurons and neural circuitry. Registered users may edit. The ultimate goal is advance the field of Neuromics by creating an encyclopedia of neurons and neural circuitry. NOTE: The database is no longer being maintained due to lack of funding.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

Atlas of developing human brain for studying transcriptional mechanisms involved in human brain development. One of the BrainSpan datasets, Exon microarray summarized to genes, is presented. It is a downloadable archive of files containing normalized RNA-Seq expression values for analysis.

• Resource
• SciCrunch
• 16 years ago - by Anonymous

Atlas of developing human brain for studying transcriptional mechanisms involved in human brain development. One of the BrainSpan datasets, Exon microarray summarized to genes, is presented. It is a downloadable archive of files containing normalized RNA-Seq expression values for analysis.

• Resource
• SciCrunch
• 16 years ago - by Anonymous