Curator Dashboard

Computes both spliced and unspliced alignments at high accuracy while taking advantage of base quality information and splice site predictions.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Collection of far reaching initiatives designed to transform research capabilities and improve translation of research into practice. Program consists of three major themes: new pathways to discovery, research teams of future, and reengineering clinical research enterprise.

• Resource
• SciCrunch
• 16 years ago - submitted by Timothy Tsui

The NIH Clinical Center is the nation's largest hospital devoted entirely to clinical research. Clinician-investigators translate scientific observations and laboratory discoveries into new approaches to diagnosing, treating, and preventing disease. The Clinical Center was recognized with the 2011 Lasker~Bloomberg Public Service Award for serving as a model research hospital—providing innovative therapy and high-quality patient care, treating rare and severe diseases, and producing outstanding clinician-scientists whose collective work has set a standard of excellence in biomedical research. About 1,500 clinical research studies are in progress at the Clinical Center. Half are studies of the natural pathogenesis of disease, especially rare diseases, which often are not studied anywhere else. What researchers learn by studying rare diseases adds to the basic understanding of common diseases. Most other studies are clinical trials, the first tests of new drugs and therapies in people. The clinical trials at the Clinical Center are predominantly Phase I and Phase II—first-in-human to test safety and efficacy. Clinical and laboratory research is conducted shoulder-to-shoulder, and this tandem approach drives all aspects of the Clinical Center's operations. More than 400,000 research volunteers have participated in clinical research studies at the Clinical Center since the hospital opened in 1953. Each year, the center sees 10,000 new research participants, of which there are two types: patient volunteers and healthy volunteers. Patient volunteers are people with specific diseases or conditions who help medical investigators learn more about their condition or test new medications, procedures, or treatments. A healthy volunteer is a person with no known significant health problems who plays a vital role in research to test a new drug, device, or intervention. At the Clinical Center, clinical research participants are active partners in medical discovery, a partnership that has resulted in a long list of medical milestones, including the first cure of a solid tumor with chemotherapy, gene therapy, use of AZT to treat AIDS, and successful replacement of a mitral valve.

• Resource
• SciCrunch
• 18 years ago - submitted by Andrea Stagg

Supports and provides leadership for population- and clinic-based research on the causes, prevention, and clinical care of cardiovascular, lung, and blood diseases and sleep disorders. Research includes a broad array of epidemiological studies to describe disease and risk factor patterns in populations and to identify risk factors for disease; clinical trials of interventions to prevent disease; studies of genetic, behavioral, sociocultural, and environmental influences on disease risk and outcomes; and studies of the application of prevention and treatment strategies to determine how to improve clinical care and public health. The Division also supports training and career development for these areas of research. The Division is organized into four major components: the Epidemiology Branch, the Clinical Applications and Prevention Branch, the Women''s Health Initiative Branch, and the Office of Biostatistics Research.

• Resource
• SciCrunch
• 15 years ago - submitted by Andrea Stagg

Perform robusts scientific and clinical research leading to a better understanding of biology and clinical pathology. We have built a strong basic science foundation and coupled it closely with innovative technology development and outstanding clinical research both at the NIH Clinical Center and in partnership with local hospitals. The purview of our research is broad, encompassing investigations into the basic principles of molecular, cellular, and organ-level biology and their relationship to disease. Some current areas of fundamental interest include single molecule structure; protein assembly; molecular and cell biology; cell signaling and motility; membrane trafficking; physiology; systems biology; engineering and technology development. Insights into disease mechanisms derived from basic studies form the basis for translational research into new diagnostic and therapeutic approaches. DIR investigators also conduct concept-based clinical studies in the areas of interventional and surgical cardiology; pulmonary medicine; sickle cell anemia; bone marrow transplant; and hematologic disorders. The Center for Population Studies located in Framingham Massachusetts and associated with the Framingham Heart Study focuses on Epidemiology of cardiovascular disease. Providing state-of-the-art training in basic, translational, and clinical research for the next generation of scientific and clinical leaders is a high priority. This program provides opportunities for scientists and trainees to work together towards a better understanding of molecular machines, the cell, the body, and ultimately the treatment of human diseases.

• Resource
• SciCrunch
• 14 years ago - submitted by Andrea Stagg

DCVS provides leadership and supports basic, clinical, population, and health services research on the causes, prevention, and treatment of cardiovascular diseases. DCVS represents the union of two previously existing divisions, the Division of Cardiovascular Disease (DCVD) and the Division of Prevention and Population Sciences (DPPS). The Division fosters research in disease areas, such as atherothrombosis, heart attack and heart failure, high blood pressure, stroke, atrial and ventricular arrhythmias, sudden cardiac death, adult and pediatric congenital heart disease, cardiovascular complications of diabetes and obesity, and other cardiovascular disorders. Technology development for the diagnosis and treatment of cardiovascular disorders is also supported. Research also includes a number of well-known epidemiological cohort studies that describe disease and risk factor patterns in populations; clinical trials of interventions to prevent disease and to prevent or modulate risk factors; studies of genetic, behavioral, sociocultural, health systems, and environmental influences on disease risk and outcomes; and studies of the application of prevention and treatment strategies to determine how to improve clinical care and public health. The Division supports training and career development for these areas of research. In addition to the Office of the Director, the Division is organized operationally as 3 Offices and 3 Programs that oversee 8 Branches.

• Resource
• SciCrunch
• 14 years ago - submitted by Andrea Stagg

DBDR supports research on the causes, prevention, and treatment of nonmalignant blood diseases, including anemias, sickle cell disease, and thalassemia; premalignant processes such as myelodysplasia and myeloproliferative disorders; hemophilia and other abnormalities of hemostasis and thrombosis; and immune dysfunction. Funding encompasses a broad spectrum of research ranging from basic biology to medical management of blood diseases. The Division has a major responsibility for research to assure the adequacy and safety of the Nation''s blood supply. The Division also has a leading role in applying scientific advances in transfusion medicine and stem cell biology to the development of new cell-based therapies to repair and regenerate human tissues and organs. DBDR has three branches: the Blood Diseases Branch, the Thrombosis and Hemostasis Branch, and the Transfusion Medicine and Cellular Therapeutics Branch.

• Resource
• SciCrunch
• 14 years ago - submitted by Andrea Stagg

• Organization
• SciCrunch
• 14 years ago - submitted by Andrea Stagg

Private research university based in New York City with historical campus in Greenwich Village.

• Organization
• SciCrunch
• 16 years ago - submitted by Stephen Larson

Medical university that specializes in health sciences, medical arts, public advocacy, and allied health profession training.

• Organization
• SciCrunch
• 17 years ago - submitted by Andrea Stagg

Public research university in Newark, New Jersey. Founded in 1881 with the support of local industrialists and inventors especially Edward Weston

• Organization
• SciCrunch
• 13 years ago - submitted by Andrea Stagg

NEDO actively undertakes the development of new energy and energy-conservation technologies, verification of technical results, and introduction/dissemination of new technologies (e.g., support for introduction). Through these efforts, NEDO promotes greater utilization of new energy and improved energy conservation. NEDO also contributes to a stable energy supply and resolution of new energy and improved energy conservation. NEDO also contributes to a stable energy supply and resolution of global environmental problems by promoting the demonstration of new energy, energy conservation and environmental technologies abroad based on knowledge obtained from domestic projects. Enhancement of Japan''s industrial competitiveness NEDO pursues research and development of industrial technology, which is the foundation for Japan''s industrial competitiveness, with the goal of commercialization of advanced new technology. Drawing on the combined efforts of industry, academia and government as well as its sophisticated management know-how, NEDO carries out projects to explore future technology seeds as well as mid- to long-term national projects that form the basis of industrial competitiveness. It also supports research related to practical application.

• Resource
• SciCrunch
• 13 years ago - submitted by Andrea Stagg

The Networks of Centres of Excellence (NCE) fosters multi-disciplinary, multi-sectoral partnerships between academia, industry, government and not-for-profit organizations. It supports academic research, the commercialization of products and ideas, and the development of significant Canadian business advantages. The partnerships that this initiative cultivates result in ideas that are transformed into economic and social benefits for all Canadians.

• Resource
• SciCrunch
• 16 years ago - submitted by Andrea Stagg

Dutch Ministry responsible for education, culture, science, research, gender equality and communications.This organization also strives to make a good work environment for teachers, artists and researchers.

• Resource
• SciCrunch
• 16 years ago - submitted by Andrea Stagg

• Resource
• SciCrunch
• 14 years ago - submitted by Andrea Stagg

• Resource
• SciCrunch
• 14 years ago - submitted by Andrea Stagg

Polish scientific research organization and part of Polish Academy of Sciences headquartered in Warsaw, Poland. Leading institution in country in field of neurobiology, molecular biology, and biochemistry. Member institution of Global Network for Molecular and Cell Biology within UNESCO.

• Organization
• SciCrunch
• 16 years ago - submitted by Andrea Stagg

Public, nonprofit research institute in the United States focused on advancing veterans health research.

• Organization
• SciCrunch
• 15 years ago - submitted by Andrea Stagg

The National Natural Science Foundation of China (NSFC) is an organization directly affiliated to the State Council for the management of the National Natural Science Fund. # In accordance with the guiding principles, policies and plans for the development of science and technology in China and by adopting the operating mechanisms for the National Natural Science Fund which conform to the socialism market economic system, NSFC supports basic research and some of applied research, identifies and fosters talented researchers in the realm of science and technology, accelerates the progress of science and technology, and promotes the socioeconomic development in China by giving full play the guidance and coordinating role of the National Natural Science Fund from the central government. # NSFC is in charge of the management of the National Natural Science Fund. It compiles and promulgates the annual Guide to Programs for basic research and some of applied research, handles applications of research projects, and organizes peer review and select the best projects to support. It endeavors to create an academic environment conducive to innovation. # NSFC cooperates with the Ministry of Science and Technology to formulate the principles, policies and plans for the development of basic research in China. When entrusted, it provides consultation and undertakes related assignments on major issues for the development of high technology and applied research in China. # NSFC gives help and support to other Chinese foundations in natural sciences. # NSFC establishes contacts with governmental departments in charge of science and technology, science foundations and related academic organizations in other countries and carries out international cooperation and exchange. # NSFC is responsible for the administration, supervision and guidance of the subordinated bodies. # NSFC undertakes other tasks entrusted by the State Council and the State Leading Group for Science and Technology and Education.

• Resource
• SciCrunch
• 13 years ago - submitted by Andrea Stagg

Government institution participating in the health care system fulfilling governmental health policy and European Union recommendations that is responsible for the quality, safety and efficacy of medicinal products and medical devices available on the Polish market. It carries out research connected with quality of medicinal products and with application of new analytical methods. Microbiological examinations concerning presence of bacterial virulence factors, estimation of specific antibodies levels as well as determination of drug resistance of clinical microorganisms are performed as well. All departments of the Institute offer services concerning complex evaluation of medicinal products and medical devices. Microbiological expert''s opinions and genetic analyses are offered as well.

• Organization
• SciCrunch
• 15 years ago - submitted by Andrea Stagg