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Software that calculates the coverage of high-throughput short-reads against a genome of reference and summarizes it per feature of interest (e.g. exon, gene, transcript). The data can be normalized as ''RPKM'' or by the ''DESeq'' or ''edgeR'' package.
A database that houses annotations of human splice isoforms. It adds reliable protein structural and functional data and information from cross-species conservation. A visual representation of the annotations for each gene allows users to easily identify functional changes brought about by splicing events. In addition to collecting, integrating and analyzing reliable predictions of the effect of splicing events, it also selects a single reference sequence for each gene, termed the principal isoform, based on the annotations of structure, function and conservation for each transcript.
Database that classifies human transcription factors based on the characteristics of their DNA-binding domains. It comprises six levels (superclasses, classes, families, subfamilies, genera and factor species), two of which are optional (subfamilies and factor species). The full classification can also be obtained as html document and as ontology in obo-format., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
A public database holding PCR primers for popular DNA methylation analysis methods to prevent time-consuming primer design and experimental optimisation.
Software for automatic detection of absolute segmental copy numbers and genotype status in complex cancer genome profiles measured by single-nucleotide polymorphism (SNP) arrays. The method is based on pattern recognition of segmented and smoothed copy number and allelic imbalance profiles. The method performs well even for poor-quality data, low tumor content, and highly rearranged tumor genomes.
A database for histone mutations and their phenotypes.
A database of CpG islands and analytical tools for identifying comprehensive methylation profiles in cancer cells.
Datbase and web-based system for visualization and analysis of genome-wide methylation data of human cancers.
This blog reflects the workings of a group of scientists working at the intersection of public health microbiology and bioinformatics.
A blog about genetics, genomics, and medical research.
Online community for industry news and careers for life science professionals.
Community building portal that serves over 3,000 members from more than 70 countries by addressing scientific policies, providing access to high quality publications, organizing meetings, and serving as a portal to information about training, education, employment, etc.
Organization that serves the scientific and educational needs of bioinformatic practitioners and the general public. They develop and maintain computational resources to facilitate world-wide communications and collaborations between people of all educational and professional levels. They provide and promote open access to the materials and methods required for, and derived from, research, development and education.
A sequence verification pipeline where users can submit trace files to verify if a clone''s physical sequence matches its reference sequence.
Software for the analysis of microarray data with a MATLAB implemented platform with a GUI that integrates all steps of microarray data analysis including automated data import, noise correction, filtering, normalization, statistical testing, clustering, classification and annotation.
Software that can use large collections of genomic data and Bayesian integration to predict coregulated gene modules, the conditions of regulation, and the consensus binding motifs for regulation.
An R package that provides an interactive environment to explore biclusters identified in gene expression data.
A Python library designed to simplify biclustering tasks.
A model-based technique for biclustering that is clustering rows and columns simultaneously.
Works to strengthen laboratories serving the public''s health in the US and globally.