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NMR facility provides state-of-the-art ultra-high field (14 and 18 Tesla) instruments that enable researchers to characterize protein structure at atomic resolution (along with the characterization of small molecules). Technical support and training are available for all aspects of project development. Experiments include structure elucidation of small molecules (e.g. synthetic molecules, natural products, and small peptides etc.) to studying advanced protein-ligand interactions.

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 22, 2024. Laboratory for Developmental Biology was established to help scientists at the Institute of Molecular Medicine and the University of Texas conduct research that requires the production of transgenic and knock-out animal models of human diseases.

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• SciCrunch
• 14 years ago - by Anonymous

An Portal, Core facility

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• 14 years ago - by Anonymous

Provides ICH-guidelines-compliant glycosylation analysis services. EGC is the analytical services branch of Procognia Ltd. Services include: N-link glycan Analysis by HPLC and Mass spectrometry O-link glycan Analysis by HPLC and Mass spectrometry Profiling and quantitative analysis of sialic acid Quantitative Monosaccharide Analysis High Throughput Analysis Using GlycoScope

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. Compound screening facility that has several drug-like compound collections available that amount to a total of about 74,000 compounds and a human siRNA library that targets almost 8,000 genes. State-of-the-art liquid handling systems and detection technologies are available for screening in-house or custom collections in 96- or 384-well plate format. The platform is compatible with biochemical assays, cell-based assays in a broad range of cellular systems and assays in the model plant Arabidopsis thaliana. Its core activities consist of managing the VIB screening collections, assisting researchers in assay development / automation and performing high-throughput screenings. After hit clustering and selection, the VIB-CSF team can contribute in structure-activity analysis, IC50 measurements, cytotoxicity analysis, secondary screening for hit validation and counter screening for specificity analysis.

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. The mission of the Proteomics and Metabolomics Facility is to serve as an enabling resource for research and development programs at Colorado State University. We strive to build instrumental capabilities that exceed the normal resources of individual research programs, and make those technologies available as a shared resource. We also aim to provide an environment rich in expertise and educational resources, and to foster collaboration across the CSU community and beyond.

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. Protein Chemistry Technology Core was established to provide efficient, high quality services to researchers in the academic community. The services presently offered include peptide synthesis and Edman protein sequencing. Our facility, its state-of-the-art instrumentation, and computer software is constantly upgraded to ensure the highest possible level of support. It is our aim to provide quality performance and offer experienced support, both through our products and people.

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• SciCrunch
• 14 years ago - by Anonymous

Core is equipped with a wide variety of technologically advanced instruments essential for cutting edge biomedical discovery and therapeutic development research. TRLab is composed of two major units. The Computational Bioinformatics Unit houses graphic workstations and modeling programs that enable in silico virtual screening and rational drug design applications. The Therapeutic Screening Unit houses a number of specialized instruments that enable a broad range of automated and multiplexed biological analyses in a throughput manner. The core mission of the TRLab has been to provide investigators with a state-of-the-art technological platform and technical expertise to advance translational research endeavors in the School of Pharmacy and at USC.

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• SciCrunch
• 14 years ago - by Anonymous

An Portal, Core facility

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• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 23,2024. Shipley Consulting, LLC is a private company specializing in advising customers on how to optimize their standard qPCR runs or focused mRNA and miRNA arrays, new qPCR assay design and post-design validation, tips on complying with the MIQE Guidelines, and how to apply automation to qPCR successfully.

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• SciCrunch
• 14 years ago - by Anonymous

Japan Bioinformatics KK is a Tokyo based biotechnology company specializing in bioinformatic software and data analysis. Products: Simbiot: Secure, easy-to-use, web and cloud-enabled software for management and analysis NGS data. SimGene: Free iOS and Android app for access to gene annotation information. SimAlign: Free iOS and Android app interfacing to NCBI BLAST+ service. Services include RNA-Seq, ChIP-Seq, miRNA-Seq, CAGE-Seq, mutation detection for amplicons, exomes and whole genomes as well as de-novo assembly and annotation of small genomes and transcriptomes. Project management services are also offered.

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• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 16,2024. Portal and core facility.

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• 14 years ago - by Anonymous

Gene By Gene offers a full suite of genetic services, including clinical gene tests, exome sequencing, genome sequencing. In addition, the recent acquisition of bioinformatics experts, Arpeggi Inc., core also offers a full end-to-end solution for sequencing projects and bioinformatics.

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• SciCrunch
• 14 years ago - by Anonymous

Located in the new Northwest Corner building on the Morningside campus of Columbia University in New York City, the Columbia University Chemical Probe Synthesis Facility (CPS facility) is a shared resource that assists researchers in designing and synthesizing small molecule probes for stem cell research projects. The CPS facility offers expertise, advice and services in the following areas: 1. Virtual screening and computational design of small molecules 2. Organic synthesis of individual compounds, building blocks or libraries of compounds 3. Drug metabolism/pharmacokinetics (DMPK) and metabolic profiling of small molecules

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• SciCrunch
• 14 years ago - by Anonymous

The Marvell Nanofabrication Laboratory at the University of California, Berkeley is a multidisciplinary facility that serves research and education in the areas of integrated circuits (ICs) and systems, micro/nanofabrication technologies, micro/nanoelectromechanical (MEMS/NEMS) systems, advanced materials and interdisciplinary applications of microelectronics. This facility offers processing for both 4 inch and 6 inch substrates (wafers).

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• 14 years ago - by Anonymous

Cutting-edge mass spectrometers deliver extremely high mass accuracy and resolution to elucidate the identity and quantity of small molecules. Metabolomics Laboratory Services: Qualitative and quantitative analysis of small molecules - Molecular mass determination - Structural elucidation - Quantification Targeted and discovery modes of analysis - Quantitative analysis of targeted metabolites - Metabolite profiling for differential comparisons between experimental groups - High-throughput sample analysis The Metabolomics Laboratory is supported by awards from the National Institutes of Health, including a Shared Instrumentation grant (1S10RR031586-01) and a supplement to the Clinical and Translational Sciences Award (3UL1RR025767-03S1).

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• 14 years ago - by Anonymous

Cancer specific CNV caller for Next Generation sequence.

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• SciCrunch
• 13 years ago - by Anonymous

DIYgenomics provides crowdsourced health research study protocol design and operation in pre-clinical and disease cohorts. Founded in 2010, the mission of DIYgenomics is the realization of preventive medicine through the integrated study of multiple health data streams. The generalized hypothesis for DIYgenomics studies is that one or more genetic polymorphisms (mutations) may result in out-of-bounds phenotypic biomarker conditions (for example, low Vitamin B blood levels), that may be ameliorated through personalized intervention.

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• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15, 2024. The mission of the X-ray Crystallography Core Laboratory is to provide state-of-the-art resources to researchers at the University of Texas Health Science Center at San Antonio, and to external users, enabling the detailed 3-D analyses of biological macromolecules that play important roles in human health. This is a full service core in that it not only offers access to sophisticated equipment and technologies but also offers advice and technical assistance in sample preparation. Services are also provided to investigators without funding to facilitate the development of pilot data for new potentially fundable projects, as core resources permit. If priority of usage becomes an issue, this will be decided by the Core Director in consultation with the other principal scientists based on the feasibility of the projects, their scientific merits and their relevance to human health.

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 22, 2024. UTHSCSA Orthopaedics Bone and Mineral High-Resolution 3D Imaging Facility is a NIH-funded imaging facility equipped with two ex-vivo desktop microCT systems, a reference point indenter and a furnace. The non-destructive nature of microCT imaging allows the researcher to strengthen his/her research by using the same sample for histology or biomechanical testing after microCT imaging. Advantages of Micro-CT - Micro-CT allows for extremely high-resolution, non-destructive, 3D imaging. - No staining, sectioning, or sample preparation needed - Samples can be frozen or fixed - Since Micro-CT is non-destructive, other assays may be carried out after, thereby increasing the amount of data per sample - Data acquisition is a rapid process, allowing for a speedy return of samples

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• SciCrunch
• 14 years ago - by Anonymous