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Core facility that provides the following services: Whole blood processing service, Cell surface staining, Cell subset enrichment service, Flow cytometry service, ELISPOT service, CFSE lymphoproliferation analysis service, Regulatory T cell conversion service, Multi-plex cytokine assay service, Flow cytometry assay service, Cell separation service. They are committed to assisting at all stages in the scientific process - from experimental design to data analysis - to meet the needs of faculty and other investigators. <BR/><BR/>DartLab is a Shared Resource that is used both by basic scientists and by clinicians carrying out mechanistic studies for clinical trials. Services are also available to non-Dartmouth clients. The consolidated Shared Resource moves beyond the simple provisioning of technical services to making complex experiments possible by providing scientific and technological support for implementing advanced, high-complexity assays in a cost-effective way, and by providing a mechanism for the acquisition of new methodologies. They carry out a spectrum of immunoassays and can develop customized immunoassays to suit your studies. They provide dedicated instruments for your use including cell sorters, flow cytometers, an ELISPOT reader, a Bio-Plex array reader and a Sector Imager, an autoMACS and a Robosep. Whole Blood Services * Flow Cytometry * Whole blood processing * Cell Subset Enrichment * Education * Clinical Trial Studies
A portal and core facility. Contains the FISABIO sequencing and bioinformatics service.
Provides high-throughput genomics data for government, biotechnology, and pharmaceutical industry customers worldwide. Created next-gen sequencing data sets including DNA sequencing, RNA-seq, ChIP-seq, DNase-seq, and Bisulfite-seq spanning a variety of organisms ranging from humans to plants. On-site bioinformaticians and biologists are available.
MEG (Magnetoencephalography) is a neuroimaging technology for cognitive and clinical brain research. In a nutshell, MEG measures non-invasively the tiny magnetic fields generated by neuronal currents. A unique asset of MEG imaging is its unrivaled temporal resolution, reaching the millisecond time scale across the entire brain volume. On the clinical side, MEG has been typically indicated for the pre-surgical work-up of severe, drug-resistant epilepsy and the functional pre-surgical mapping of brain tumors. There is however great potential to use MEG as an instrument of choice to investigate other neurological syndromes and neuropsychiatric disorders (e.g., stroke, dementia, movement disorders, depression, etc.). Overall, MEG has strong value in revealing the dynamics of brain activity involved in subject''''s perception, cognition and responses: it has provided unique insight on the time-resolved processes ruling brain functions (resting-state dynamics, language, motor control, visual and auditory perception, etc.) and dysfunctions (movement disorders, tinnitus, chronic pain, dementia, etc.). MEG(at)McGill provides a full-suite of services related to MEG and MEG/EEG studies. This includes a variety of training programs for use of the MEG and related data acquisition and analysis software, Brainstorm.
A genomics data service provider offering genomic project management, data analysis, and bio-IT consulting services.
Applied Biosciences is a small miority owned LLC. We specialize in hormone assays from the very small (30 g to the 5000 kg elephant) to the very large. We have a vast experience of knowledge in the endocrine field. Our experts are board certified in animal pharmacology as well as theriogenology. Combined with our Endocrinologist, there is over 75 years of experience with animal medicine and more specficially endocrinology of many animal species.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. Portal, Core facility
Creative Bioarray is a well-recognized service provider propelled by integrity, expertise and the desire to contribute to simplify, improve, and accelerate research speed of the scientists by providing the highest standard quality research products and services. Since it founded, Creative Bioarray had recognized that an important obstacle to make development of basic bioscience and preclinical researches using human specimens is the lack of access to reference materials. Consequently, Creative Bioarray was determined to be the first commercial entity specialized in building up the largest tissue-sharing platform by integrating the detailed clinical information of all the tissue samples. http://www.creative-bioarray.com/home.asp
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. Sanford-Burnham''s Protein Production Core offers state-of-the-art resources with advanced biochemical engineering and bioprocessing capabilities. Specialized protein production scale-up services (65L bacterial or 25-50L insect/mammalian cell production) include optimization of production runs. Analytical services include measurement of protein-protein and protein-small molecule interactions using a variety of approaches such as surface plasmon resonance and isothermal titration calorimetry. Assistance in experimental design and technical support are also provided by the Core''s knowledgeable staff.
The Microscopy Core Facility at BGSU offers a range of services, including Scanning electron microscopy (SEM) and Transmission electron microscopy (TEM).
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 22, 2024. Microbiology & Quality Associates, Inc., located in the San Francisco Bay Area, is a service organization providing a variety of services to life sciences companies. Our services include: contract biotech development services, testing services, consulting, validation services, calibration services, training, and scientific resources. MQA is FDA registered. Our Quality System comply with GXP regulations and ISO 17025/9001. We provide services to a wide variety of companies in biotechnology, pharmaceutical, medical devices, nutritional products, dialysis centers, semiconductors, and other industries. MQA staff has many years of hands-on experience at pharmaceutical, biotechnology and medical device companies.
THIS RESOURCE IS NO LONGER IN SERVCE, documented January 25, 2019. Core brings together leading technologies for sample preparation, protein separations, identification and characterization. Through collaboration with the Computational Research Support Unit, Biosciences and Proteomics Technologies is developing new systems for electronic laboratory information management and bioinformatics. The research facility offers services and training in proteomics discovery technologies to Australian and international researchers from academia and industry. Core has expertise in experimental design, custom method development, sample preparation, complex mixture fractionation and protein separations. Sydney Biosciences and Proteomics Technologies also manages the core infrastructure and operations for the Faculty of Science's extensive Biomedical and Bioscience research facilities.
The MAU is comprised of five separate characterisation nodes: (1) Electron microscopy and microanalysis (2) Scanning probe microscopy (3) X-ray characterisation (4) Electrical measurement and characterisation (5)Optical characterisation. As well as a materials fabrication and processing equipment suite. This research infrastructure is supported by an academic Director, a Research Laboratory Manager and three highly experienced and highly skilled Professional Officers.
The research facility in Chemical Technologies pulls together the resources of several well equipped laboratories specialising in chemistry and materials science. The facility is particularly focused on chemical, forensic, material and biochemical analysis, and materials technology, and is set up to serve the needs of Australian industry and academia in these areas. Specialties of the facility include the physical and mechanical characterization of engineering materials, and the chemical and physical characterisation of forensic and pharmaceutical samples. The facility is equipped to produce and characterise a diverse range of organic and inorganic materials, and is backed by a team of experienced researchers.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024.
For applications including proteomics, drug discovery, immunogenicity, and food analysis, state-of-the-art Surface Plasmon Resonance (SPR) technology allows for label-free, real-time biomolecular interaction analysis. Using purified preparations or complex mixtures, binding interactions between proteins, lipids, carbohydrates, nucleic acids, small molecules, and cells/viruses can be examined quantitatively in their native state with low sample consumption. In a typical experiment, the ligand (_������������bait_������_) is immobilized to a gold-plated sensor chip and repeated injections of analyte (binding partner _������������target_������_) are then flowed overtop.
Facility is dedicated to conducting preclinical and clinical brain imaging research in the field of mental health. Researchers at the Douglas CIC use several brain imaging methods, including MRI scanners, to non-invasively understand the brain structure and functions that are altered by mental illnesses. Provides platform to analyse brain imaging data from functional and structural neuroimaging techniques.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. Protein production can be a significant bottleneck during early phase drug discovery. Our production facilities are fully equipped and staffed to help researchers produce proteins in bacteria, yeast or insect cells. Whether the protein is hopelessly insoluble or difficult to produce in quantity, the core staff is ready to work with individuals to turn failure into success. The Cell Biology facility provides researchers access to cell sorting and analysis for target characterization and validation. The BD FACS Aria II sorter is BSL2 capable permitting levels of safety in cell sorting not available in most flow cores. A second BD Canto II flow cytometer provides automated sampling for analytical flow cytometry. Fully automated Zeiss Axiovert 100 deconvolution and Lecia DM 6000 (laser microcapture) microscopes provide tools for cell imaging and content analyses.
The chemodiversity core facility offers a library of natural product-derived crude extracts, fractions and pure compounds for screening. Gas chromatography high-resolution mass spectrometry (MS) analysis, liquid chromatography MS targeted separation and high throughput screening (targeting solid tumor cell lines, anti-microbial activity, permeability and drug solubility determination) are provided. The services also include general chromatography (MPLC, HPLC) and spectrometric characterization (UV, IR) as well as microbiology workspace (biosafety cabinets), synthesis activities and training. Our facility offers advanced instrumentation (GC/MS Q-TOF, IR, UV, MPLCs, HPLCs, liquid handling robots, biosafety cabinets, and other essential lab equipment), consultation and services for sample isolation and analysis, derivatization and scale-up. Sample preparation and safety training are also available for commercial and USF clients using our chromatographic and analytical instrumentation.
The Mass Spectrometry, Biological Applications and High-Throughput Proteomics Facility is dedicated to the identification and quantification of components associated with complex biological matrices. The main goal of our lab is to produce high quality data related to any biological or environmental sample, i.e. cancer, Alzheimer_������_s, diabetes, cardiovascular disease, and parasitology, to name a few. To see a full list of facility activity, please visit our listed website.