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Case Western Reserve University Labs and Facilities
An Portal, Core facility
- Resource
- SciCrunch
- 14 years ago - by Anonymous
CWRU Athymic Animal and Xenograft Core Facility
The Athymic Animal and Xenograft Core Facility provides facilities for breeding and housing of athymic nude mice (NCRnu/nu) and rats, and other immunodeficient mice. The core provides pathogen-free facilities for experimentation using immunodeficient animal hosts and normal human cells and human tumor cell xenografts. Core staff maintain and monitor animals housed in the facility, and provide users with a variety of services, including transportation, health reports, animal handling, and experimental procedures. The staff will also train users in animal handling and experimental procedures. Entry to the animal facilities is controlled by key card access and is limited to employees who are listed on an IACUC-approved protocol, have enrolled in an animal contact Occupational Health program, and have completed access training. Experimental procedures, listed below, are provided either at the Case facility or in the Animal Tumor Core (ATC) at the Cleveland Clinic Taussig Cancer Institute. The Taussig Cancer Institute ATC was established in 2002 to help principal investigators at the Cleveland Clinic and CWRU perform tumor experiments, angiogenesis studies, and pharmacokinetic studies in mice. The ATC conducts syngeneic murine tumor experiments, and human xenograft (athymic nude mouse) tumor experiments. In addition, the ATC has developed several orthotopic human carcinoma models: HT-29 colon, HCT-116 colon, SW480 colon (all metastasize to liver), ACHN renal, A549 lung, multiple prostate, bladder, melanoma and ovarian tumors. ATC services utilize murine models to facilitate in vivo cancer drug screening, drug evaluation, and drug development. The core''''s goal is to help in evaluation of new pharmacologic agents by providing data on tumor growth, metastasis, angiogenesis, and gene expression. The facility also provides consultation services to assist the investigator in all aspects of animal tumor model development.
- Resource
- SciCrunch
- 14 years ago - by Anonymous
New York University Labs and Facilities
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 15,2024. Portal, Core facility.
- Resource
- SciCrunch
- 14 years ago - by Anonymous
Cornell University Labs and Facilities
An Portal, Core facility
- Resource
- SciCrunch
- 14 years ago - by Anonymous
Columbia University Labs and Facilities
An Portal, Core facility
- Resource
- SciCrunch
- 14 years ago - by Anonymous
SUNY at Stony Brook Labs and Facilities
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 23,2024. Portal, Core facility
- Resource
- SciCrunch
- 14 years ago - by Anonymous
University of Rochester Labs and Facilities
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 16,2024. Portal, Core facility
- Resource
- SciCrunch
- 14 years ago - by Anonymous
Montclair University Microscopy and Microanalysis Research Laboratory Core Facility
Interdisciplinary research, teaching and service facility equipped with scanning and transmission electron microscopes, an atomic force microscope, and the ancillary instruments. Provides microscopic imaging, X-ray analysis, and specimen preparation services for biological, pharmaceutical, and materials scientific research. The MMRL consist of four individual microscope rooms, the Histology laboratory, and sample preparation and chemical storage areas.Graduate- and upper-undergraduate-level training is offered in the operation of electron microscopes, sample preparation, and thick/thin sectioning. Currently, MMRL houses transmission electron, scanning electron microscopes, and atomic force microscope. The microscopes available for use include: - Hitachi H-7500 transmission electron microscope - Hitachi S-3400N variable pressure scanning electron microscope with x-ray analysis and digital imaging - Hitachi S-2460N scanning electron microscope with x-ray analysis In addition, the following items are also available for MMRL users: - Three Leica 2030 rotary paraffin microtome - Two LKB ultramicrotomes - A LKB 7800 glass knife maker - Leica Reichert Ultratrim - Denton critical point dryer - Denton sputter coaters (Desk II and Desk IV) - Denton Vacuum evaporators (DV-502A) - Liquid nitrogen dewars (various sizes) - A Leica stereo dissecting microscope - A Tissue-TeK VIP Tissue Processor - A Tissue-TeK II Embedding Center
- Resource
- SciCrunch
- 14 years ago - by Anonymous
University of Nebraska Lincoln Labs and Facilities
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 16,2024. Portal, Core facility
- Resource
- SciCrunch
- 14 years ago - by Anonymous
University of Nebraska Medical Center Labs and Facilities
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 16,2024. Portal, core facility.
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- SciCrunch
- 14 years ago - by Anonymous
North Dakota State University Labs and Facilities
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 15,2024. Portal, Core facility
- Resource
- SciCrunch
- 14 years ago - by Anonymous
Trevigen Cell Assays
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 19,2024. Trevigen Cell Assays (TCA), a division of Trevigen, Inc., was established in 2008 to conduct contract research work for the pharmaceutical, biotechnology, government and academic segments of the medical research market. TCA specializes in designing and conducting assays for lead compounds and genotoxic screening based on DNA damage and repair as well as cancer cell behavior.
- Resource
- SciCrunch
- 14 years ago - by Anonymous
Wake Forest University Labs and Facilities
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. An Portal, Core facility
- Resource
- SciCrunch
- 14 years ago - by Anonymous
University of North Carolina at Chapel Hill Labs and Facilities
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 16,2024. Portal, Core facility.
- Resource
- SciCrunch
- 14 years ago - by Anonymous
PHSA Centre for Translational and Applied Genomics
PHSA Laboratories'''' Centre for Translational and Applied Genomics (CTAG) is a a CAP Accredited genomics and molecular pathology core facility supported by a world class team of molecular pathologists with diverse clinical and research interests and technical skills. CTAG operates at PHSA agencies including the BC Cancer Agency, BC Centre for Disease Control, BC Children''''s Hospital and BC Women''''s Hospital & Health Centre. CTAG offers a broad range of analytical services to the public and private sectors. As a division of PHSA Laboratories, CTAG''''s mission is to develop novel laboratory tests to improve the management of a diverse spectrum of disorders including cancer, infectious diseases, and inherited syndromes.
- Resource
- SciCrunch
- 14 years ago - by Anonymous
Duke University Labs and Facilities
An Portal, Core facility
- Resource
- SciCrunch
- 14 years ago - by Anonymous
Montana State University Labs and Facilities
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 16,2024. Portal, Core facility
- Resource
- SciCrunch
- 14 years ago - by Anonymous
Dartmouth Transgenics and Genetic Constructs Shared Resource
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 12,2026.Core facility that provides the following services: Cigarette smoke exposure analysis service, Oocyte injection for transgenic animal production, Transgenic mice consultation, Generation of chimeric mice from ES cells, Transgenic lines establishment, Genotyping service, Tail biopsies and other services, Humanized mice production. The mission of the TGCSR is to support the generation and utilization of genetically modified mice by members of the Dartmouth research community. The support starts with intellectual support in planning and designing transgenic experiments provided by consultation with the TGCSR director. The TGCSR is now able to offer not only assistance with design of genetic constructs but also the production of genetic constructs for use in transgenic animal production through recombineering in either yeast or E. coli. TGCSR provides a full range of ES cell manipulation services. The tasks of manipulating the mouse embryo are fully provided by the TGCSR either in house or through an established relationship with the University of Vermont. Jackson labs is now providing cryopreservation services to protect and preserve valuable transgenic mouse lines. The TGCSR can also provide genotyping and mouse husbandry services. As currently organized, the TGCSR can provide the full range of services required to design, generate and maintain transgenic mouse lines. TGCSR currently maintains two specialized transgenic lines that express Cre or Flp in the germline for genetic manipulation of transgene/knockouts in vivo. TGCSR has a fully equipped embryo manipulation laboratory in the Borwell animal facility and an adjoining 4 room suite of mouse husbandry rooms.
- Resource
- SciCrunch
- 14 years ago - by Anonymous
University of Mississippi Medical Center Labs and Facilities
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 16,2024. Portal, Core facility
- Resource
- SciCrunch
- 14 years ago - by Anonymous
WUSTL School of Medicine Embryonic Stem Cell Core
The Murine Embryonic Stem Cell Core has been created to help you create mutations in murine embryonic stem cells. The core has several missions including development of state-of-the-art reagents for the production of targeted mutations in embryonic stem cells, the creation of quality-controlled embryonic stem cell lines, and the teaching of methods for embryonic stem cell culture and manipulation. The core utilizes quality-controlled cells developed here at Washington University.
- Resource
- SciCrunch
- 14 years ago - by Anonymous
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