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THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. We will design and produce DNA constructs for any purpose: Mutations/Deletions Knockout/Transgenic constructs Epitope tags & Fusion proteins Protein expression constructs Viral gene delivery constructs RNAi & related constructs Cost is generally about $300 per construct Turnaround time usually 5 business days

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• SciCrunch
• 13 years ago - by Anonymous

Core Facility within the Center For Personalized Diagnostics offers both Sanger DNA sequencing and Illumina NGS services (HiSeq 2000). DNASU is also a central repository for plasmid clones and collections. We currently store and distribute over 191,000 plasmids including over 75,000 human and mouse plasmids, full genome collections from numerous organisms, the protein expression plasmids from the Protein Structure Initiative as the PSI:Biology-Materials Repository (PSI:Biology-MR), and both small and large collections from individual researchers.

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• SciCrunch
• 14 years ago - by Anonymous

The Department of Chemistry''s Magnetic Resonance Facility underwent a major upgrade in 2006 and in 2011 with the addition of three NSF funded spectrometers: Varian Direct Drive 500 MHz and 600 MHz NMR''s and a Bruker EMX PLUS EPR.

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• SciCrunch
• 13 years ago - by Anonymous

Richman Chemical offers a full range of custom synthesis and manufacturing services to life science and chemical industries. Our technical capabilities include: complex multi-step organic synthesis, emulsion or solution polymerization, inorganic custom synthesis (including organometallics), electronic chemicals, stereochemically pure compounds For our pharmaceutical clients, we also provide drug product formulation, compounding, and packaging.

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• SciCrunch
• 13 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Molecule serves the needs of your businesses, both large and small. We are based in Silicon Valley with local and international labs. We are a team of experts who have worked for world-class companies over 2 decades and provide service in a wide range of chemistry, formulation and new technology development areas of medical device and drug control release products. We provide both contract work and consulting service in wet chemistries (customer design and synthesis) and formulation development. We have spent so much time to accumulate experience so your work can be developed in the shortest amount of time.

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• SciCrunch
• 13 years ago - by Anonymous

The Central Proteomics Facility (CPF) of Oxford University offers proteomics mass spectrometry services and expertise to academic and commercial organisations. The facility is quipped with state-of-the-art Orbitrap and Q Exactive Orbitrap mass spectrometers. The facility routinely perfroms idenitification, post-translational modification and protein quantitation work using SILAC.

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• SciCrunch
• 13 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30, 2023. AKESOgen is a biomarker, genomics and pharmacogenomics contract research organization that services the academic, pharmaceutical, biotechnology and agricultural sectors. AKESOgen performs biomarker profiling and genomics services utilizing different types of markers (e.g. DNA, RNA, methylation) for the R&D market. AKESOgen establishes and validates biomarkers in the Clinical Trials arena. AKESOgen provides expertise in biobanking. AKESOgen is CLIA certified.

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• SciCrunch
• 13 years ago - by Anonymous

Core facility that aids investigators and trainees with high performance computation in proteomics, as well as other omics type applications needing efficient analysis of large-scale biological data sets. The ability to incorporate proteomics into translational and clinical biomedical research is critical for the discovery of therapeutic interventions and high fidelity biomarkers of disease and response to therapy. The Core provides state-of-the-art services, training, and bioinformatics-driven data analysis to the Meharry translational research community.

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Portal, Core facility

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• SciCrunch
• 13 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 22,2024. Transgenic and Gene Targeting Core is a full-service facility designed to assist you in generating genetically engineered mouse models for biomedical research. Our services include gene targeting in embryonic stem cells, the generation of ES cell-derived knockout and knockin mice, transgenic mice (conventional and BAC transgenic mice) and the cryo-preservation of mouse lines. The latter service is of particular importance for investigators that have long-term projects with non-commercial mouse lines. Changes in the genetic make-up of your mouse lines that occur spontaneously over time (gene drift) and disease outbreaks can significantly affect the outcome of your research. It is therefore advisable to preserve your mouse lines, providing you with a backup of your valuable research tools. We currently offer both embryo cryopreservation as well as sperm cryopreservation for this purpose.

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• SciCrunch
• 14 years ago - by Anonymous

The new iPSC Core generates custom-designed iPSCs from mouse and human cells, including disease-specific human iPSCs. iPSCs from other species are currently under development. The Core is currently using both lentiviral- and sendai viral vector systems to deliver reprogramming factors to cells. Both systems are efficient, with the latter system having the advantage to generate iPSCs with a non-DNA-integrating vector system.

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Portal, Core facility

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• SciCrunch
• 13 years ago - by Anonymous

The Chemical GMP Synthesis Facility is a state-of-the-art manufacturing facility for small and large molecule therapeutics for clinical trials. The CGSF provides services for drug discovery, process research, development and early clinical manufacturing of pharmaceutical drug substances (APIs) that meet FDA requirements. www.cityofhope.org/chemicalgmp

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• SciCrunch
• 14 years ago - by Anonymous

The NCSU Analytical Instrumentation Facility (AIF) is a North Carolina State University resource for materials characterization. AIF operates a number of major analytical instruments providing quality analyses for all who require it. These instruments are operated and maintained by a professional staff who are experienced in the design and implementation of materials characterization experiments. For those who desire hands on involvement in their analyses, AIF staff trains users to operate analytical instrumentation, design efficient analytical experiments, and properly interpret the resulting data. In addition, AIF staff is involved in the development and/or enhancement of analytical techniques in a continuing effort to provide the level of capabilities required by the ever evolving needs of the NCSU research community. AIF provides short courses as well as formal classroom instruction to insure that NCSU''''s future engineers and scientists can, upon graduation, take with them an understanding of modern analytical techniques and an understanding of the instrumentation required to implement them.

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Our contract antibody service is designed to be highly flexible to ensure we meet the individual needs of our customers. Whether you are looking for a complete start to finish service or simply one aspect such as clone yield optimisation, then SCIPAC can meet your needs. Our service caters for both monoclonal antibodies as well as recombinant antibodies.

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• SciCrunch
• 13 years ago - by Anonymous

Service resource which makes imaging technology available to investigators on UTHSCSA campus and neighboring scientific community. Core Optical Imaging Facility offers access to technology for imaging of living cells, tissues, and animals, consultation, education and assistance regarding theory and application of optical imaging techniques, technical advice on specimen preparation techniques and probe selection.

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• SciCrunch
• 13 years ago - by Anonymous

Provides complete sequencing and data analysis service based around second generation Illumina Genome Analyzer (GAIIx) and Illumina MiSeq sequencing platform. They also offer Agilent Bioanalyzer RNA and DNA analysis, Covaris focussed acoustic shearing of nucleic acids and tissues, qPCR assay design, execution and analysis, oligonucleotide synthesis and capillary electrophoresis (CE/Sanger) sequencing. Offers expertise in advanced DNA and RNA technologies.

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• SciCrunch
• 14 years ago - by Anonymous

Provides advice, technical assistance and access to advanced scientific equipment.Provides education and training for graduate students. Supports research activities of other Universities and assists local business ventures in solving scientific problems.

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• SciCrunch
• 13 years ago - by Anonymous

Provides instrumentation for proteomics and metabolomics studies, including protein, peptide and metabolite separations, MS instrumentation for protein, peptide and metabolite analysis, and data systems, software, and bioinformatics tools for data archiving and analysis. Proteomics Core performs routine analytical proteomics services, including target discovery, identification and quantitation, and also provides platforms for functional proteomics using variety of strategies for protein separation, sub-proteome enrichment, post-translational modification analysis, and quantitation.

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• SciCrunch
• 14 years ago - by Anonymous

The UNC Animal Models Core Facility provides the full range of mouse genetic modification services, reagents and related technologies. The Core''s services are available to both UNC and Non-UNC clients. Transgenic (pronuclear injection) animals can be generated in C57BL/6, FVB or C57BL/6 X DBA2 hybrid strains. Services for creating transgenic mice include transgene design, construct generation, isolation of the transgene fragment, pronuclear microinjection, founder genotyping and breeding. The core also offers the full suite of services for BAC (bacterial artificial chromosome) recombineering and microinjection of BAC transgenes. Gene targeting services are available in ES cells from C57BL/6 or 129P2/Ola strains. Other strains available upon request. Gene targeting services include design and cloning of targeting vectors, creating gene-targeted ES cells, blastocyst microinjection of the ES cells to create transmitting chimeras and chimera breeding for germline transmission. The core can also provide Southern blot validation and blastocyst microinjection of ES cells from EUCOMM, KOMP or other consortia. Additional services include Cre- or Flp-mediated excision in ES cells or in vivo, chromosome counting, PCR screening and Southern blotting. Rat model production is also available.

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• SciCrunch
• 14 years ago - by Anonymous