Curator Dashboard

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024.

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• SciCrunch
• 13 years ago - by Anonymous

For applications including proteomics, drug discovery, immunogenicity, and food analysis, state-of-the-art Surface Plasmon Resonance (SPR) technology allows for label-free, real-time biomolecular interaction analysis. Using purified preparations or complex mixtures, binding interactions between proteins, lipids, carbohydrates, nucleic acids, small molecules, and cells/viruses can be examined quantitatively in their native state with low sample consumption. In a typical experiment, the ligand (_������������bait_������_) is immobilized to a gold-plated sensor chip and repeated injections of analyte (binding partner _������������target_������_) are then flowed overtop.

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• SciCrunch
• 14 years ago - by Anonymous

Facility is dedicated to conducting preclinical and clinical brain imaging research in the field of mental health. Researchers at the Douglas CIC use several brain imaging methods, including MRI scanners, to non-invasively understand the brain structure and functions that are altered by mental illnesses. Provides platform to analyse brain imaging data from functional and structural neuroimaging techniques.

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. Protein production can be a significant bottleneck during early phase drug discovery. Our production facilities are fully equipped and staffed to help researchers produce proteins in bacteria, yeast or insect cells. Whether the protein is hopelessly insoluble or difficult to produce in quantity, the core staff is ready to work with individuals to turn failure into success. The Cell Biology facility provides researchers access to cell sorting and analysis for target characterization and validation. The BD FACS Aria II sorter is BSL2 capable permitting levels of safety in cell sorting not available in most flow cores. A second BD Canto II flow cytometer provides automated sampling for analytical flow cytometry. Fully automated Zeiss Axiovert 100 deconvolution and Lecia DM 6000 (laser microcapture) microscopes provide tools for cell imaging and content analyses.

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• SciCrunch
• 14 years ago - by Anonymous

The chemodiversity core facility offers a library of natural product-derived crude extracts, fractions and pure compounds for screening. Gas chromatography high-resolution mass spectrometry (MS) analysis, liquid chromatography MS targeted separation and high throughput screening (targeting solid tumor cell lines, anti-microbial activity, permeability and drug solubility determination) are provided. The services also include general chromatography (MPLC, HPLC) and spectrometric characterization (UV, IR) as well as microbiology workspace (biosafety cabinets), synthesis activities and training. Our facility offers advanced instrumentation (GC/MS Q-TOF, IR, UV, MPLCs, HPLCs, liquid handling robots, biosafety cabinets, and other essential lab equipment), consultation and services for sample isolation and analysis, derivatization and scale-up. Sample preparation and safety training are also available for commercial and USF clients using our chromatographic and analytical instrumentation.

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• SciCrunch
• 14 years ago - by Anonymous

The Mass Spectrometry, Biological Applications and High-Throughput Proteomics Facility is dedicated to the identification and quantification of components associated with complex biological matrices. The main goal of our lab is to produce high quality data related to any biological or environmental sample, i.e. cancer, Alzheimer_������_s, diabetes, cardiovascular disease, and parasitology, to name a few. To see a full list of facility activity, please visit our listed website.

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• SciCrunch
• 14 years ago - by Anonymous

NMR facility provides state-of-the-art ultra-high field (14 and 18 Tesla) instruments that enable researchers to characterize protein structure at atomic resolution (along with the characterization of small molecules). Technical support and training are available for all aspects of project development. Experiments include structure elucidation of small molecules (e.g. synthetic molecules, natural products, and small peptides etc.) to studying advanced protein-ligand interactions.

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 22, 2024. Laboratory for Developmental Biology was established to help scientists at the Institute of Molecular Medicine and the University of Texas conduct research that requires the production of transgenic and knock-out animal models of human diseases.

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• SciCrunch
• 14 years ago - by Anonymous

An Portal, Core facility

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• SciCrunch
• 13 years ago - by Anonymous

Provides ICH-guidelines-compliant glycosylation analysis services. EGC is the analytical services branch of Procognia Ltd. Services include: N-link glycan Analysis by HPLC and Mass spectrometry O-link glycan Analysis by HPLC and Mass spectrometry Profiling and quantitative analysis of sialic acid Quantitative Monosaccharide Analysis High Throughput Analysis Using GlycoScope

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• SciCrunch
• 13 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. Compound screening facility that has several drug-like compound collections available that amount to a total of about 74,000 compounds and a human siRNA library that targets almost 8,000 genes. State-of-the-art liquid handling systems and detection technologies are available for screening in-house or custom collections in 96- or 384-well plate format. The platform is compatible with biochemical assays, cell-based assays in a broad range of cellular systems and assays in the model plant Arabidopsis thaliana. Its core activities consist of managing the VIB screening collections, assisting researchers in assay development / automation and performing high-throughput screenings. After hit clustering and selection, the VIB-CSF team can contribute in structure-activity analysis, IC50 measurements, cytotoxicity analysis, secondary screening for hit validation and counter screening for specificity analysis.

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• SciCrunch
• 13 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. The mission of the Proteomics and Metabolomics Facility is to serve as an enabling resource for research and development programs at Colorado State University. We strive to build instrumental capabilities that exceed the normal resources of individual research programs, and make those technologies available as a shared resource. We also aim to provide an environment rich in expertise and educational resources, and to foster collaboration across the CSU community and beyond.

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. Protein Chemistry Technology Core was established to provide efficient, high quality services to researchers in the academic community. The services presently offered include peptide synthesis and Edman protein sequencing. Our facility, its state-of-the-art instrumentation, and computer software is constantly upgraded to ensure the highest possible level of support. It is our aim to provide quality performance and offer experienced support, both through our products and people.

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• SciCrunch
• 13 years ago - by Anonymous

Core is equipped with a wide variety of technologically advanced instruments essential for cutting edge biomedical discovery and therapeutic development research. TRLab is composed of two major units. The Computational Bioinformatics Unit houses graphic workstations and modeling programs that enable in silico virtual screening and rational drug design applications. The Therapeutic Screening Unit houses a number of specialized instruments that enable a broad range of automated and multiplexed biological analyses in a throughput manner. The core mission of the TRLab has been to provide investigators with a state-of-the-art technological platform and technical expertise to advance translational research endeavors in the School of Pharmacy and at USC.

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• SciCrunch
• 13 years ago - by Anonymous

An Portal, Core facility

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• SciCrunch
• 13 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 23,2024. Shipley Consulting, LLC is a private company specializing in advising customers on how to optimize their standard qPCR runs or focused mRNA and miRNA arrays, new qPCR assay design and post-design validation, tips on complying with the MIQE Guidelines, and how to apply automation to qPCR successfully.

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• SciCrunch
• 13 years ago - by Anonymous

Japan Bioinformatics KK is a Tokyo based biotechnology company specializing in bioinformatic software and data analysis. Products: Simbiot: Secure, easy-to-use, web and cloud-enabled software for management and analysis NGS data. SimGene: Free iOS and Android app for access to gene annotation information. SimAlign: Free iOS and Android app interfacing to NCBI BLAST+ service. Services include RNA-Seq, ChIP-Seq, miRNA-Seq, CAGE-Seq, mutation detection for amplicons, exomes and whole genomes as well as de-novo assembly and annotation of small genomes and transcriptomes. Project management services are also offered.

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• SciCrunch
• 13 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 16,2024. Portal and core facility.

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• SciCrunch
• 13 years ago - by Anonymous

Gene By Gene offers a full suite of genetic services, including clinical gene tests, exome sequencing, genome sequencing. In addition, the recent acquisition of bioinformatics experts, Arpeggi Inc., core also offers a full end-to-end solution for sequencing projects and bioinformatics.

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• SciCrunch
• 13 years ago - by Anonymous

Located in the new Northwest Corner building on the Morningside campus of Columbia University in New York City, the Columbia University Chemical Probe Synthesis Facility (CPS facility) is a shared resource that assists researchers in designing and synthesizing small molecule probes for stem cell research projects. The CPS facility offers expertise, advice and services in the following areas: 1. Virtual screening and computational design of small molecules 2. Organic synthesis of individual compounds, building blocks or libraries of compounds 3. Drug metabolism/pharmacokinetics (DMPK) and metabolic profiling of small molecules

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• SciCrunch
• 14 years ago - by Anonymous