Curator Dashboard

The Experimental Therapeutics Program (ETP) is a program established within the unique MNI environment to pursue a mission of bridging basic research in neurobiology and immunology with human studies of neurological and immune-mediated diseases. The ETP accomplishes this mission through the establishment of core laboratory platforms that integrate fundamental research activities with rigorous studies on human biological samples derived from well-characterized patient populations. The goal of the program is to expedite the development and formal evaluation of emerging therapies aimed at halting and ultimately reversing disability caused by neurological disease.

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• SciCrunch
• 14 years ago - by Anonymous

Core facility offers instrumentation for routine flow cytometry and cell sorting. Offers expertise and services including assisting in setting up flow cytometry experiments, acquiring, analyzing and interpreting data, data presentation and data storage, providing training with analyzers and software usage.

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• SciCrunch
• 14 years ago - by Anonymous

Software tool as data transformation algorithm that restructures data in such a way that the transformed message is more compressible. Used for large scale compression of genomic sequence databases.

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• SciCrunch
• 13 years ago - by Anonymous

Self use flow cytometry facility. All new users must be trained by the facility manager over two orientation sessions and be approved to use the equipment in the facility.

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• SciCrunch
• 14 years ago - by Anonymous

Core facility that positions digital imaging resources right where the research is being done: in Harvard Medical School''s quad-based basic science departments. The convenience of these locations makes it easy for researchers to access digital imaging expertise when faced with research imaging questions. This accessibility and convenience is supplemented by substantial web-based assistance, making Research Imaging Solutions a 24/7 resource. Seminars, Workshops and printed training materials guide faculty, students, post-docs and lab personnel on supported imaging hardware and software products. Supported hardware and software packages includes: Adobe products including Acrobat, Photoshop, and Illustrator; ACD Canvas; Microsoft Office applications including Word, PowerPoint and Excel; film recorders, slide and flatbed scanners, and color output devices such as color laser printers, poster printers and photo quality printers.

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• SciCrunch
• 14 years ago - by Anonymous

Core facility that provides the following services: SNP genotyping, qPCR for CNV detection / confirmation, Genetic analysis services, DNA extraction, quantification, sample preparation, tracking, and storage. This resource provides custom genotyping (SNP, other), qPCR for CNV detection/confirmation, DNA extraction, quantification, sample preparation, tracking, and storage, and related services to further the PNGU mission of identifying and characterizing the genetic basis of psychiatric, behavioral, and neurodevelopmental disorders and to translate these discoveries to improvements in clinical care and public health.

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 4th, 2023. Handles both low-level (instrument-specific, or upstream) informatics as well as higher-level (hypothesis testing and generation oriented, or downstream informatics). CHIBI also has the scientific responsibility for the high-end computing needed to process the genomic data.

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• SciCrunch
• 14 years ago - by Anonymous

Core facility that provides the following services: Rodent and Porcine Islet Isolation Services, Training Services. The main objective of the Islet Isolation Core is to provide Islets of Langerhans to investigators in the Boston area and beyond. By receiving islets from the Core one is assured of consistent high quality and purity of islets for experiments. The Core can isolate rodent and neonatal porcine islets. This leaves the investigator to concentrate on experiments rather than the complexity of islet isolation. The Core can buy the animals or the investigator can provide their own, such as special transgenic mice. Over the last five years the Core has isolated more than 10 million islets. They also provide training and advice. The Core can provide training not only for the isolation procedure but islet viability, islet size measurement, GSIS (Glucose Stimulated Insulin Secretion), STZ-induced diabetes, transplantation under the kidney capsule, and islet graft retrieval.

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• SciCrunch
• 13 years ago - by Anonymous

Core provides centralized, standardized, accurate, consistent, and timely longitudinal, multimodality anatomic, volumetric and functional tumor metrics including CT, MR, PET/CT and other nuclear medicine imaging studies to evaluate therapeutic response for patients enrolled in DF/HCC oncologic clinical trials. TIMC supports more than 30 tumor response assessment criteria including but not limited to RECIST 1.1, iRECIST, Lugano, LYRIC, IWCLL and RANO. Results of tumor metric analyses are offered on password-protected secure web-based report.

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• SciCrunch
• 14 years ago - by Anonymous

Core provides support to life science researchers with data analysis and experimental design from sequence analysis, microarrays, proteomics and beyond.

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. Portal, Core facility

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• SciCrunch
• 13 years ago - by Anonymous

Formerly the NERCE NMR Resource. Nuclear magnetic resonance spectroscopy is a powerful tool for studying structural and conformational parameters of molecules. This tool is vital for the chemical analysis of both small molecules (like those discovered in small-molecule screens) and large molecules, such as carbohydrates and proteins found to have potential biologic importance. This is a user-based NMR facility; users run their own experiments on the NMR spectrometer.

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• SciCrunch
• 14 years ago - by Anonymous

Core facility that provides the following services: NextGen sequencing, Data Analysis. The NextGen Core is a collaboration between the Department of Molecular Biology, the Center for Human Genetics Research, the Center for Computational Biology, and the Executive Committee on Research (ECOR). Currently, the Core operates using a single Ilumina HiSeq instrument, accompanied by Illumina''''s cBot for cluster generation. This upgrade from our Genome Analyzer II doubled our capacity and greatly increased the data amount, quality, and stability over extra-long reads. The Core is located in the state-of-the-art Richard Simches Research Center on Cambridge St. as part of the MGH main campus in Boston. The many multi-investigator groups in the building - including those that study human genetics, stem cells, genomics, and more - make it the perfect location for the Core to service the researchers in those groups. The majority of customers come from MGH, but they also service customers at other academic medical centers and industry.

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 22, 2024. The Fluorescence Microscopy and Imaging Core Laboratory is a multi-user facility located in the Department of Pathology and Laboratory Medicine at The University of Texas Medical School Houston, within the Texas Medical Center. Its purpose is to allow research scientists access to state of the art Fluorescence Microscopes and Imaging equipment, to foster experimentation for the further understanding of scientific phenomena in many diverse areas of clinical and basic research.

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15, 2024. Xeno Diagnostics is a Contract Research Organization specializing in cell-based assays. Models include Non-human Primates, Porcine, Bovine, and Human. Services can be run under GLP, non-GLP, or CLIA regulations.

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• SciCrunch
• 13 years ago - by Anonymous

Chiral Polyamines is a discovery-driven product and service oriented life science company offering chirally pure discovery chemicals, custom synthesis and technology services for the research, biotechnology and pharmaceutical market. Chiral Polyamines produces a broad product line of over 75,000 fully customizable chiral polyamines for research and drug discovery. We commit ourselves to provide researchers with novel high quality chiral products in a variety of formats.Chiral Polyamines also focuses on custom research and development. Our highly skilled scientists are experts in combinatorial chemistry techniques as well as biochemical and synthetic organic chemistry.

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• SciCrunch
• 13 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. Mission- Developmental Histology The mission of the Developmental Histology unit is to provide 1. Timely high quality histology services to the Yale community 2. Access to tissue services from Yale Pathology archives 3. To maximize the value of the resources in the Yale Pathology Tissue Archive. 4. To provide Tissue Microarrays to assess multiple tissue samples Mission- Yale Pathology Tissue Services To provide the maximum amount and quality of human tissue for research at Yale University without impacting diagnostic quality, accuracy and safety in anatomic pathology.

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• SciCrunch
• 13 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 19,2024. We provide 16S sequencing to allow you to learn about the microbiome, using similar technology and protocols to the Human Microbiome Project, a $173 million project by the National Institutes of Health, concluded in 2012. Compare human and non-human microbiomes, examine the effect of disease on the microbiome (and vice versa), examine the effect of clinical trials on the microbiome, or simply do citizen science. We''re hear to help! Also, contact us to join our research consortium at consortium(at)ubiome.com.

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• SciCrunch
• 13 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. Main goal of the Vector facility is development and implementation of viral vectors and viral vector-based techniques, which allow manipulating neural circuits and characterizing neural populations in laboratory animals. We also see the Vector facility as a pole of shared resources and expertise. Many systems of recombinant viruses have been used in a wide number of applications, namely as gene delivery tools. Recombinant adeno-associated virus (rAAV) is very frequently a gene delivery vector of choice, especially in the field of gene therapy.

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVCE, documented January 24, 2019. Core provides advisory services in study planning and data mining (debugging, analysis and interpretation of results) resulting from the sequencing of DNA and RNA. Core's goal is to help extract all possible information from sequencing data which will be useful for projects. Applications: Sequence trimming and quality control (quality index, length of sequences, etc...). Taxonomic assignment of prokaryotic 16S rDNA sequences. Comparative ecological analysis of environmental and/or clinical microbial communities based on 16S rDNA taxonomy. Assembly and/or annotation of genomes and metagenomes. Transcriptome annotation. Determination of SNPs in resequencing studies in bacterial systems. Sending Data. Sequences can be submitted in any of the usual formats (FASTA, SFF, FASTQ, etc) along with a description of the experimental design (including sufficient details) and the relevant information associated with each sample in order to perform the necessary analyses (factors associated with the samples, sub-samples, etc.).

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• SciCrunch
• 14 years ago - by Anonymous