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NIAID research strives to understand, treat, and ultimately prevent the myriad infectious, immunologic, and allergic diseases that threaten millions of human lives. Major areas of investigation: * Acquired Immunodeficiency Syndrome (AIDS) * Asthma and Allergic Diseases * Biodefense * Emerging and Re-emerging Infectious Diseases * Enteric Diseases * Fundamental Immunology * Genetics and Transplantation * Immune-Mediated Diseases * Influenza * Pathogen Genomics * Sexually Transmitted Infections (STIs) * Vaccine Development * Drug Research and Development * Antimicrobial Resistance * Minority and Women''s Health

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• SciCrunch
• 16 years ago - submitted by Andrea Stagg

An international professional association of 24,000 neurologists and neuroscience professionals dedicated to promoting the highest quality patient-centered neurologic care. They provide guidance and inspiration through education, information, policy development and advocacy for our members and their patients. The Academy''s professional website is only one of the domains associated with the AAN: * TheBrainMatters.org, public & patient education website * m.AAN.com, mobile AAN.com for members * Neurology journal * Neurology Now, patient magazine * Neurology Today, magazine for neurology professionals The AAN is committed to bringing its members the highest quality continuing medical education and professional education opportunities. The Academy''s Education programs cover the spectrum of neurological disorders, from the most prevalent to newly emerging issues. The AAN also provides a wide range of program formats, including in-depth print, convenient online, and hands-on workshop options. The AAN Annual Meeting brings together more than 10,000 neuroscience professionals for one of the world''s largest neurology gatherings. It has long been a leading showcase for the latest developments in scientific research, and the place to honor peers at the forefront of the work. The AAN offers a variety of publications, news, blogs, jobs, and practice guidelines.

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• SciCrunch
• 17 years ago - by Anonymous

Software package that contains functions for inference of target gene regulation by miRNA, based on only target gene expression profile.

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• SciCrunch
• 13 years ago - by Anonymous

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• SciCrunch
• 17 years ago - submitted by Eddy Kim

ExDom is a unique database developed for the comparative visualization and analysis of exon-intron structure of protein domains in seven eukaryotic genomes (Homo sapiens, Mus musculus, Bos taurus, Rattus norvegicus, Danio rerio, Gallus gallus and Arabidopsis thaliana). The ExDom database integrates 3744 protein domains annotated in the Pfam database to their corresponding exon-intron structures in 40,390 genes annotated in the RefSeq database and provides a unique platform for integrated comparative analysis of exon-domain relationships. The comparative graphical viewer in ExDom, implemented in Flash MX 6, allows users to query for a domain of interest, retrieve all proteins across different organisms which have this common domain, and then, visualize and compare the exon-intron structures of the domain in these proteins. Homo sapien genome, Mus musculus genome, Bos taurus genome, Rattus norvegicus genome, Danio rerio genome, Gallus gallus genome, Arabidopsis thaliana genome

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• SciCrunch
• 17 years ago - by Anonymous

Database compiles all complete or nearly complete SSU (small subunit) and LSU (large subunit) ribosomal RNA sequences. Sequences are provided in aligned format. Alignment takes into account secondary structure information derived by comparative sequence analysis of thousands of sequences. Additional information such as literature references, taxonomy, secondary structure modles and nucleotide variability maps, is also available.

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• SciCrunch
• 17 years ago - by Anonymous

A research program of the NIA which focuses on neuroscience, aging biology, and translational gerontology. The central focus of the program's research is understanding age-related changes in physiology and the ability to adapt to environmental stress, and using that understanding to develop insight about the pathophysiology of age-related diseases. The IRP webpage provides access to other NIH resources such as the Biological Biochemical Image Database, the Bioinformatics Portal, and the Baltimore Longitudinal Study of Aging., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

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• SciCrunch
• 17 years ago - by Anonymous

RetNet provides tables of genes and loci causing inherited retinal diseases, such as retinitis pigmentosa, macular degeneration and Usher syndrome, and related information. This information is provided to the research community and other interested individuals for research purposes only. The information should not be used for medical or commercial purposes. Although we strive for accuracy and completeness, we cannot guarantee that all information is correct and complete. We welcome comments and suggestions!

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• SciCrunch
• 17 years ago - by Anonymous

The School of Psychology at UNSW is located in the Faculty of Science and has approximately 30 academic staff, 1600 undergraduate students and 150 postgraduate students. Members of the School study a diverse range of topics such as children''s development of language and knowledge, how mood affects our social behavior, teamwork in organizations, bias in eyewitness testimony, the brain mechanisms underlying pleasure and pain, the effect of aging and brain damage on memory, how the visual system perceives a three-dimensional world, and the causes and treatment of psychological disorders ranging from psychopathy to depression and post-traumatic stress. We offer a broad range of undergraduate courses in the major areas of psychology that not only communicate contemporary knowledge but also train general skills in research design, critical thinking, statistical analysis and written and oral communication. Our postgraduate programs in clinical, organisational and forensic psychology provide intensive professional training, and our PhD program offers the opportunity for advanced study in a range of specialised research fields. What makes our School distinctive is the quality of our academic staff. We earn more competitive research funding and publish more Tier 1 journal articles per academic than any other School in Australia. Our academics are very well connected within Australia and internationally. Historically, the School has played a leadership role in research, teaching and professional issues. The School has an academically rigorous but supportive culture, excellent research facilities, and offers great opportunities for students, visitors and collaborators.

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• SciCrunch
• 16 years ago - submitted by Eddy Kim

Supplies laboratory automation systems, reagent kits, stock solutions, proteins, and accessories for protein researchers. Tools to automate protein purification, liquid handling, and protein crystallization. Our reagents and stock solutions are available individually, in convenient screens, and as custom products. As the demands of protein research continue to grow, we now provide high purity proteins.

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 5, 2022. Core facility that provides the following services: DNA isolation service, RNA isolation service, Cloning and endotoxin-free plasmid preparation service, Virus plaque assay, SIV p27 protein ELISA, HIV p24 protein ELISA with sample prep, Real time PCR titer of lentivirus prep with sample prep, Coculture of animal tissues/fluids service, Virus plaque purification service, Virus growth curve service, Protein determination, Bradford method, Crude viral DNA prep service, Gradient purified viral DNA prep service, Southern blot for viral DNA, Viral Real-time PCR, RhCMV Real-time PCR, HSV 1/2 B virus antibody ELISA, single dilution service, RhRRV antibody ELISA, single dilution, RhSFV antibody ELISA, single dilution, SIV antibody ELISA, single dilution, Virus antibody ELISA, RhCMV antibody ELISA, Virus neutralization service, Polyclonal IgG preparation, SIV in vitro susceptibility, p27 ELISA, Vaccinia (MVA) virus plaque assays, Antiviral antibody determination by ELISA, SIV in vitro infectivity (leukocytes) service, Viral load quantification with qPCR, Virus detection using nested PCR, Virus stock production, Cytomegalovirus plaque assays and purification, Cytomegalovirus stock and vector production, Western blot service for viral protein, Cell sample processing and banking, Nucleic acid isolation and purification service, Virus cloning and plasmid preparation service, Vaccinia (MVA) virus stock and vector production. The Core''''s overall goal is to advance the efforts of the Oregon National Primate Research Center (ONPRC), the Vaccine and Gene Therapy Institute (VGTI), and collaborative research programs focused on nonhuman primate (NHP) infectious disease models and those using viral vectors as tools to modify genes or deliver macromolecules through provision of expertise, reagents, standardized assays, and training in the use of infectious viral agents in their research programs. The MVSC provides specialized expertise and infrastructure in five essential areas: * Virus identification and quantification in clinical specimens * Production of virus stocks, virus vectors, and viral antigen preparations * Serologic assays to assess host antiviral immune responses * Maintenance of cell stocks and sample processing * Development of new reagents and standardized assays The MVSC has considerable experience and expertise in both viral diagnostics and production, particularly for AIDS and CMV pathogenesis and vaccine studies, and in adenoviral vector production.

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• SciCrunch
• 14 years ago - by Anonymous

Since its inception in 1951, the fermentation facility''s goal has been to provide affordable fermentation services to a highly diverse client base. Completely renovated in 2011 the fermentation facility, which meets BL2-LS containment requirements, is comprised of four contiguous operation units: -Material Preparation Laboratory -Fermentation In-Process -Computer Control -Product Recovery Room Bio-reactor working capacities range from 10 to 800 liters. All systems are computer controlled with algorithm-based cascade-capable PID programming. In the recovery room, downstream processing includes: -Centrifugation -Filtration -Micro and Ultra-filtration -Cell Disruption With the advantage of having the world''s pharmaceutical industry in its backyard, a productive climate of industrial liaison has been the historical legacy of the facility. Many former facility students and graduates hold positions within the industry. www.waksman.rutgers.edu/fermentation/home

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 10, 2023. Our mission is to conduct research in microbial molecular genetics, developmental molecular genetics, plant molecular genetics, and structural and computational biology. We also provide a catalyst for general university initiatives, a life science infrastructure, undergraduate and graduate education, and a public service function for the State of New Jersey. The Institute employs faculty teams that concentrate on certain classes of organisms amenable to genetic analysis such as bacteria and fungi (E. coli and yeast), animal systems (e.g., Drosophila), and plants (Arabidopsis, tobacco, and maize). Although the Institute focuses on basic questions in microbial, animal, and plant research, it continues to engage in extensive technology transfer of its basic discoveries.

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• SciCrunch
• 14 years ago - by Anonymous

The Macromolecular X-ray Crystallography Core Facility of Scripps FL offers state-of-the-art equipment and resources to scientists inside and outside of the Scripps FL campus by providing crystallographic analysis of their chosen biological macromolecules. The core facility offers and operates as a full service core by performing protein crystallization, X-ray diffraction data collection (both in-house and at Argonne National Laboratory) and processing, phasing, crystallographic refinement, model building, and visualization. The structural data obtained by the core will provide scientists with a wealth of information including but not limited to biological functions, 3D-folding, ligand binding (small molecule or protein), or mutational effect of target macromolecules of their interests.

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• SciCrunch
• 14 years ago - by Anonymous

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• SciCrunch
• 17 years ago - submitted by Andrea Stagg

With the completion of the genome sequence, that offers us a variety of new genes to study, and advances in combinatorial chemistry, that delivers large numbers of synthetic compounds to test, high__������throughput screening (HTS) is becoming a necessary research endeavor. We specialize in HTS of G protein__������coupled receptors (GPCRs). Ligand recognition is quantified in binding experiments or monitored by second messenger responses. One technology that we use is the FLIPR technology that allows for real__������time fluorescent measurements.

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• SciCrunch
• 14 years ago - by Anonymous

Preclinical organization offers advanced services and collaborative projects in pharmacology, neurochemistry and tissue metabolism in experimental models of human diseases. Bioanalytical services include chromatographic and mass spectrometry techniques, as well as, immunoassays and enzymatic assays for quantification of neurotransmitters and other signaling molecules, metabolites, and drug levels in microdialysis samples, plasma, CSF, urine, culture media, cell lysates and tissue extracts.

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• SciCrunch
• 14 years ago - by Anonymous

Advanced Analytical Testing Service (AATS) is dedicated to providing premium testing services for food, dietary supplement, biotechnology and cosmetic industries. AATS is established on our clients'' greatest satisfaction with our sample processing, testing method development and post-testing consultation. Our goal is to report authentic and accurate testing results with optimal quality and minimum turnover time. AATS is FDA registered independent analytical testing provider that is familiar with cGMP, USP and ISO standards. AATS has established full quality system on personnel, training, sample receipt and handling, testing, quality control and documentation. We provide testing results of high quality, because we have a strong quality system built in our testing facilities.

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 16,2024. Portal, Core facility

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• SciCrunch
• 14 years ago - by Anonymous

The Immunohistochemistry Core, a component of the Experimental Pathology Shared Resource, is located in Bellevue Hospital within the NYULMC Department of Pathology''s Anatomic Pathology clinical space. The laboratory serves as an immunohistochemical antibody repository with a catalog of over 900 antibodies. Antibodies are in stock and available for use in the core laboratory for the collection of experimental immunohistochemistry data. The laboratory develops immunohistochemical protocols for new antibodies (commercial or proprietary) that have not been tested in fresh, frozen, fixed human or animal tissues and cells. In addition to performing manual labeling, the laboratory is equipped with two Ventana NEXES and one Discovery automated immunohistochemical staining instruments. The laboratory uses human and animal tissue micro-arrays for validation and employs a wide variety of antigen retrieval methods for protocol development. The core offers tyramide and polymer amplification methods (manual) and single or two color chromogenic immunohistochemistry. The laboratory has also commenced developing protocols and validating antibodies for immunoflorescence in frozen and FFPE tissue samples. The laboratory faculty and staff are available to provide hands-on informal training, as well as guidance and support for the design and execution of experiments involving histopathology and immunohistochemistry of human and animal cells and tissues. In conjunction with the Histopathology Core Laboratory, the Immunohistochemistry Laboratory can also assist investigators with routine and advanced histopathologic services for tissue and cell specimens (including guidance on initial processing steps: grossing/tissue preparation, processing, embedding, paraffin/frozen microtomy) for samples destined for histopathological interpretation and analysis. In addition, we offer extensive options for special and routine histochemical and immunohistochemical labeling of both human and animal model cells and tissues.

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• SciCrunch
• 14 years ago - by Anonymous