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PHSA Laboratories'''' Centre for Translational and Applied Genomics (CTAG) is a a CAP Accredited genomics and molecular pathology core facility supported by a world class team of molecular pathologists with diverse clinical and research interests and technical skills. CTAG operates at PHSA agencies including the BC Cancer Agency, BC Centre for Disease Control, BC Children''''s Hospital and BC Women''''s Hospital & Health Centre. CTAG offers a broad range of analytical services to the public and private sectors. As a division of PHSA Laboratories, CTAG''''s mission is to develop novel laboratory tests to improve the management of a diverse spectrum of disorders including cancer, infectious diseases, and inherited syndromes.
An Portal, Core facility
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 16,2024. Portal, Core facility
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 12,2026.Core facility that provides the following services: Cigarette smoke exposure analysis service, Oocyte injection for transgenic animal production, Transgenic mice consultation, Generation of chimeric mice from ES cells, Transgenic lines establishment, Genotyping service, Tail biopsies and other services, Humanized mice production. The mission of the TGCSR is to support the generation and utilization of genetically modified mice by members of the Dartmouth research community. The support starts with intellectual support in planning and designing transgenic experiments provided by consultation with the TGCSR director. The TGCSR is now able to offer not only assistance with design of genetic constructs but also the production of genetic constructs for use in transgenic animal production through recombineering in either yeast or E. coli. TGCSR provides a full range of ES cell manipulation services. The tasks of manipulating the mouse embryo are fully provided by the TGCSR either in house or through an established relationship with the University of Vermont. Jackson labs is now providing cryopreservation services to protect and preserve valuable transgenic mouse lines. The TGCSR can also provide genotyping and mouse husbandry services. As currently organized, the TGCSR can provide the full range of services required to design, generate and maintain transgenic mouse lines. TGCSR currently maintains two specialized transgenic lines that express Cre or Flp in the germline for genetic manipulation of transgene/knockouts in vivo. TGCSR has a fully equipped embryo manipulation laboratory in the Borwell animal facility and an adjoining 4 room suite of mouse husbandry rooms.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 16,2024. Portal, Core facility
The Murine Embryonic Stem Cell Core has been created to help you create mutations in murine embryonic stem cells. The core has several missions including development of state-of-the-art reagents for the production of targeted mutations in embryonic stem cells, the creation of quality-controlled embryonic stem cell lines, and the teaching of methods for embryonic stem cell culture and manipulation. The core utilizes quality-controlled cells developed here at Washington University.
A commercial contract research organization that mentions embryo culture media for IVF procedures and cell therapy on their website.
Evaluations at the tissue level are critical to musculoskeletal research. The Bone Histomorphometry Lab in the Department of Orthopedics has a rich history of conducting such in situ evaluations in both human and animal tissue. The primary expertise of the Bone Histo Lab is the processing of skeletal tissue in its calcified state for the preparation of histology slides.
The Histology Core at Lake Nona is a full-service shared resource facility that provides histological services to Sanford-Burnham researchers and investigators throughout the scientific community. The Core offers technical support, consultative, and interpretive pathology to all investigators. Tissue samples are processed with the highest industry quality standards, using state-of-the-art instrumentation. The Core also assists with experiment design as well as the development and interpretation of tests and their results. Sanford-Burnham''''s Histology Core at Lake Nona is committed to collaborating with investigators and advancing research by carrying out critical tissue specimen validation and evaluation. Equipment and Resources: - Thermo Excelsior ES Tissue Processor - Thermo Histocentre_������������������������ 3 Embedding Unit - Thermo Cytospin 4 - Thermo Microm HM355S Microtome - Thermo Printmate 450 Cassette Printer - Thermo Microm HM550 Cryostat - Thermo Microm HM650 V Vibratome with cooling unit - Thermo Microm HM450 Sliding Microtome with freezing unit - Leica IP S Slide Printer - Leica RM2235 Microtome - Leica 1900UV Cryostat - Nikon Eclipse 80i Microscope with AR Elements imaging software - Ventana Discovery XT - Tissue-Tek?? Prisma Automated Slide Stainer and Glas_������������������������ g2 Coverslipper - Aperio ScanScope XT-Brightfield - Aperio ScanScope FL-Fluorescence
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 17,2024. Independent contract laboratory. Its services include deformulation and reverse engineering, contaminant identification, purification, and component isolation from complex matrices.
An Core facility
Core aims to empower research institutes and private companies in the fields of bioinformatics, biostatistics, biotechnologies, data management and R&D. Core is organized into four specialized divisions: Sequentia Green, Sequentia Health, Sequentia Research, and Sequentia Training.
Department of Animal Sciences houses well-equipped laboratories, and has access to animal facilities and two experimental farms that are used for both undergraduate training and postgraduate research. Collaboration with the Western Cape Department of Agriculture, other tertiary institutions, non-governmental organisations and the private sector is maintained by the Department of Animal Sciences to ensure that research is current and relevant to the various animal production industries.
Core provides services to its partners in deploying genomic capabilities to bring critical solutions to both agriculture and industrial biotech operations. Core facility also provides assistance to research, biotech/pharma and government facilities. In addition to being an Agilent Certified Service Provider MOgene is also a CLIA certified genomics service facility offering one stop service and solution from Tissue/Cells to Analysis. Core offers RNA/DNA isolation, Microarrays, NextGen sequencing, Real time PCR and bioinformatics services.
Supply center and provides UNC Lineberger members and UNC colleagues with tissue culture products including stocks media, media supplements, serum, salt solutions, antibiotics, cell culture flasks and dishes, and many other in vitro cell culture and molecular biology-related items, kits and cell lines. Cell lines include normal and transformed mammalian, avian, insect, amphibian/reptile, and hybridoma cells. Services include checking Fetal Bovine Serum for quality and efficacy. TCF partners with Genetica Cell Line Services to offer qPCR-based Mycoplasma contamination testing for cell or DNA samples. Utilizes Genetica Cell Line Services for STR profiling of cell lines.
Core provides access to next generation sequencing (NGS) to investigators at UT Southwestern, at other institutions in the UT System, and at additional cost to investigators outside of the UT system. Core can receive flow cell ready samples (sequencing libraries that are prepared by the user) or perform sequencing library production for genomic libraries, RNA-SEQ applications, and small RNA (microRNA) applications. Data output routinely will provide de-multiplexing and alignment to the genome of choice using a variety of assembly and analysis programs, including CLC-Biosystems workbench, a BWA-GATK-Genotyper pipeline, a BowTie-Top Hat analysis pathway, and the Illumina ELAND DNA sequence aligner. Limited access to post sequence data analysis software is also available through the core, including both CLC-Biosystems (2 floating licenses available for on campus users) and the Genome Studio software packages.
The CSB provides an integrated platform of expertise, infrastructure and education to foster a wider use of structural biology by the UNC community. The CSB mission is to make structural biology available as a general tool to any researcher. Structures of macromolecules at atomic resolution have helped to revolutionize modern biology. Structural insight is often crucial for understanding the functions of biological macromolecules, including their interactions with small ligands (such as substrates, inhibitors, drugs) and other macromolecules (nucleic acids and/or proteins). Consequently, structural biology represents one of the pillars of basic biomedical research; it is indispensable for deciphering the details of life processes and for understanding the differences between natural and diseased states. Building on such insights, structural biology can assist in devising novel therapies, e.g., through structure-based or structure-aided drug design. The enormous information content available in high-resolution, three-dimensional structures has sparked the desire of non-structural biologists to examine the structures of the macromolecules that they study. Structural biology is technically demanding, and it requires highly specialized expertise. The CSB removes or reduces these barriers that usually prevent general researchers from engaging in structural biology-based projects by themselves.
Core provides molecular biotechnology services and current molecular genetic methods. Services include DNA and RNA Extraction, transgenic mouse genotyping, Human Cell line Authentication, Sanger DNA Sequencing, Next-Generation sequencing platforms, Microsatellite DNA Typing, Agena multiplex SNP Genotyping, Real-time PCR, NanoString Gene Expression Analysis. Specializes in custom workflows that couple services with specific research needs.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 24,2024. IBBR DNA Sequencing Facility currently offers its customers NextGen sequencing.
An Core facility