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THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 19,2024. Portal, Core facility

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• SciCrunch
• 13 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 19,2024. Portal, Core facility.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Core facility that provides the research community with the facilities and the expertise to characterize complex microbial communities from different environments.Services offered by the Core include metagenomics methods to determine the composition and function of microbial communities using amplicon, Whole Genome Shotgun (WGS) and RNA sequencing, and traditional and high-throughput quantitative (q)PCR.

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• SciCrunch
• 14 years ago - by Anonymous

The Nucleic Acid Shared Resource (NASR) provides genomic and epigenomic support for cancer research at OSUCCC-James including: Sanger-based DNA Sequencing, Next-Generation Sequencing, Genotyping, DNA Methylation analysis and Gene Expression Analysis. Additionally, the NASR provides consultation and assistance in experimental design, troubleshooting, training, development of novel methodologies and applications, and publication preparation.

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• SciCrunch
• 14 years ago - by Anonymous

The Electron Microscopy Resource Laboratory (EMRL ) at Penn is a research facility dedicated to ultrastructure analysis of biological samples by electron microscopy (EM). We offer high quality EM imaging services at low cost. With a team of experienced professional staff and state-of-the-art sample preparation and imaging equipment, the EMRL offers users a full spectrum of both transmission EM and scanning EM services.

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• SciCrunch
• 14 years ago - by Anonymous

Real-time PCR Research and Diagnostics Core Facility accepts research projects from both academic and private sector. The Core Facility can accommodate projects involving laser microdissection, RNA and DNA extractions through semi-automated nucleic acid extractions systems, cDNA synthesis and complete Real-time PCR analysis using a laser 7900 HTA FAST platform.

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 22, 2024. Core facility that specializes in the generation and analysis of genetically modified mice, including transgenic and knockout animals, is an essential technology for biomedical research. Our services include: Production of transgenic mice by pronuclear DNA microinjection and embryo transfer. Production of chimeric mice by blastocyst injection of genetically modified ES cells and embryo transfer, which is part of the procedure of producing knockout or knockin mice. Gene targeting, which involves the electroporation of a targeting vector into pluripotent mouse embryonic stem (ES) cells and the selection of gene-targeted clones. Education of investigators and advice on vector and experimental design for experiments using transgenic and knockout mice. Bioimaging: The Animal Imaging Service provides investigators the opportunity for non-invasive detection, localization, and longitudinal monitoring of primary and metastatic cancer cells in vivo, in allograft, zenograft, transgenic and knock-out mouse models. The IVIS Spectrum (Caliper Life Sciences, Hopkinton MA) uses optical imaging technology to detect bioluminescent and fluorescent reporters across the blue to near infrared wavelength region. DNA samples and ES cell lines are injected in the order in which the signed service request forms are received. Currently, the average time from receipt of the service request to injection is approximately 2 weeks. For ES Cell electroporation and expansion, success in gene targeting cannot be guaranteed due to inherent variability in the frequency of targeting different loci, and the possibility of mistakes or mutations in the targeting vector.

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• SciCrunch
• 14 years ago - by Anonymous

RARAF is dedicated to providing user-friendly radiation sources and bio-labs for research in biology, radiation biology, and radiation physics.

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. VBI trains and educates members of the laboratory animal science community on surgical refinements, biomethodologies, anesthesia and analgesia as well as a variety of other topics. VBI utilizes a global network of world-renowned experts to harmonize education and incorporate best practices into all training protocols. Though training, VBI improves the quality of research data, promotes animal welfare and enforcesrefinement, reduction, and replacement in animal research. VBI has validated competency and proficiency assessment tools that are an integral part of training and knowledge transfer. Our on-line courses have been validated to show that their use before hands-on training improves the knowledge transfer and competency of the end user.

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• SciCrunch
• 13 years ago - by Anonymous

The ANFF provides leading-edge research capability and supports excellence in science. The capability provided by ANFF enables users to process hard materials (metals, composites and ceramics) and soft materials (polymers and polymer-biological moieties) and transform these into structures that have application in sensors, medical devices, nanophotonics and nanoelectronics. It has a strong emphasis on service provision to the research community. ANFF seeks to enhance national and international collaborations and enable world-class-research.

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• SciCrunch
• 13 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVCE, documented January 23, 2019. Core functions as a multi-user resource dedicated to the development and application of various high-throughput technologies to aid in the discovery of biological macromolecules. Core provides analysis platforms for DNA (sequencing and genotyping), RNA (gene expression analysis) and proteins (proteomics). They also offer a selection of molecular biology applications (colony picking, cloning, DNA/RNA isolations).

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• SciCrunch
• 13 years ago - by Anonymous

Software for a web-enabled platform for analyzing genome variation such as copy number variation (CNV).

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• SciCrunch
• 13 years ago - by Anonymous

The electron microscopy core facility provides services and expertise in all aspects of transmission and scanning electron microscopy. Services include conventional fixation and sectioning of cells and tissues, negative staining of organelles and macromolecular assemblies, shadowing of isolated protein molecules, freeze-fracture, immunolabeling, etc. Cryo-sectioning and cryo-electron microscopy are also available. Expert consultation on all aspects of experimental planning and micrograph interpretation is provided by the facility manager, Greg Hendricks.

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• SciCrunch
• 14 years ago - by Anonymous

The UMMS Machine Shop is a support service dedicated to assisting research in a technical/mechanical manner. Although all types of basic laboratory apparatus are manufactured and repaired on a regular basis, we specialize in design and fabrication of equipment that is not commercially available. No job too big or too small, too simple or too complex. Our staff is experienced and knowledgeable in working with all plastics and composites, all metals and alloys. We have over 35 years combined of experience in biomedical design and machining experience and are always available to discuss projects either at the shop or at your location. The Machine Shop is located at the Shrewsbury Campus. Pick-up and delivery of jobs can be arranged at your convenience.

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• SciCrunch
• 14 years ago - by Anonymous

Screening facility assists researchers in developing high-throughput screening assays, performs HT screens of chemical libraries to identify new small molecules that can be used to probe biological processes of interest. Facility coordinates screening efforts of UMass Chan researchers, providing access to diverse chemical libraries and state-of-the art instruments including robotic compound transfer, liquid-handling equipment, imagers and plate readers.

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• SciCrunch
• 14 years ago - by Anonymous

The High Throughput Gene Expression/Biomarker Core Laboratory run by Drs. Tanriverdi and Freedman provides High Throughput/Rapid Gene Expression and Complete miRNA profiling analysis by using gold standard qRT-PCR with the combination of custom Integrated Fluidic Circuit (IFC) technology from Fluidigm (South San Francisco, CA). Also, high-throughput SNP and multi-plate immunoassay services are available. The core lab is located in a modular class 10,000 clean room.

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• SciCrunch
• 14 years ago - by Anonymous

The Flow Cytometry Facility, located at UMass Medical School in Worcester, provides a wide variety of cytometry services for internal and external investigators with state-of-the-art sorting and analyzing capabilities. For analysis we currently have three 4-color FACSCaliburs, a 2 laser LSR II, a 4 laser LSRII and a 5 laser LSRII. Our cell sorters include a 3 laser Beckman Coulter MoFlo XDP hi-speed cell sorter, an all digital 3 laser 11 color FACSVantage DE DiVa sorter, a 19 parameter, 5 laser FACSAria, and a 14 parameter, 4 laser FACSAria dedicated to BSL3 cell sorting. Two LSR II''s and one Calibur are dedicated for investigator self use, after training is completed. We encourage all investigators to come to the main lab at S5-322 and learn how flow cytometry can be applied to your research. Rates are based per hour and billed in 15 minute increments. Training rates are based per person, per hour. Sorting includes a 1 hour setup fee unless there is a second sort on that instument that day, in which case each sort is billed 30 minutes for setup. BSL3 Sorting is billed 30 minutes for setup in all cases

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• SciCrunch
• 14 years ago - by Anonymous

The Duke Microarray Facility provides services for the analysis of gene expression. The facility is operated jointly with the Duke Cancer Institute and provides: Affymetrix Microarrays Agilent Microarrays Real-Time PCR RNA Quality Check with Agilent Bioanalyzer The Microarray Facility also maintains a comprehensive database server to manage the massive amounts of data generated by microarray analysis. The facility provides data analysis support through various software packages as well as gene annotation support.

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 16,2024. USC Stem Cell Core facility is a CIRM funded comprehensive support center and central hub for the provision of knowledge, resources and state of the art technology to researchers working with stem cells. Our primary aims are to facilitate stem cell and biomedical research at USC and the LA area and to develop new technologies for working with pluripotent stem cells. We offer a wide range of services in the following areas: Cells and Reagents Reproducibility in experimental science is dependent on homogeneity and consistency. One of the primary aims of the USC Stem Cell Core is to standardize stem cell research by providing quality controlled cells and reagents. Equipment The USC Stem Cell Core is a shared laboratory space housing communal cell culture workstations, a state of the art imaging core, spectral karyotyping facilities, a Q-PCR machine, fully equipped molecular biology work stations and a variety of equipment for performing histological analysis. Flow cytometry and high content screening equipment are made available through the FACS core. Laboratory Space As a shared research facility we offer communal laboratory space for investigators to conduct collaborative or start up research involving stem cells. Our goal is to expand stem cell research in the LA area and to encourage collaboration between novice and seasoned researchers. Technical Assistance The USC Stem Cell Core is staffed with a team of highly experienced technicians, boasting a combined technical expertise of over 60 years. We provide comprehensive assistance, which includes a biobanking and histology service. Training and Education Training and education are pivotal to the advancement of Stem Cell Research. The USC Stem Cell Core offers a broad range of educational services including technical protocols, one on one customized training and a week long course covering human pluripotent stem cell culture techniques. Research and Development The USC Stem Cell Core Research and Development program was established with two main aims: 1) to develop and centralize new technologies for working with human pluripotent stem cells, 2) to support researchers embarking on collaborative and pilot projects.

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• SciCrunch
• 13 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 19,2024. TATI is located at the Center for Medical Research (Zentrum fuer Medizinische Forschung, ZMF) within the University of Tuebingen Clinical School (Universitaetsklinikum Tuebingen) . We are engaged in immune monitoring (cancer immunotherapy, vaccination of elderly, Alzheimer) using 14-colour flow cytometry.

• Resource
• SciCrunch
• 13 years ago - by Anonymous