We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
With the completion of the genome sequence, that offers us a variety of new genes to study, and advances in combinatorial chemistry, that delivers large numbers of synthetic compounds to test, high__������throughput screening (HTS) is becoming a necessary research endeavor. We specialize in HTS of G protein__������coupled receptors (GPCRs). Ligand recognition is quantified in binding experiments or monitored by second messenger responses. One technology that we use is the FLIPR technology that allows for real__������time fluorescent measurements.
Preclinical organization offers advanced services and collaborative projects in pharmacology, neurochemistry and tissue metabolism in experimental models of human diseases. Bioanalytical services include chromatographic and mass spectrometry techniques, as well as, immunoassays and enzymatic assays for quantification of neurotransmitters and other signaling molecules, metabolites, and drug levels in microdialysis samples, plasma, CSF, urine, culture media, cell lysates and tissue extracts.
Advanced Analytical Testing Service (AATS) is dedicated to providing premium testing services for food, dietary supplement, biotechnology and cosmetic industries. AATS is established on our clients'' greatest satisfaction with our sample processing, testing method development and post-testing consultation. Our goal is to report authentic and accurate testing results with optimal quality and minimum turnover time. AATS is FDA registered independent analytical testing provider that is familiar with cGMP, USP and ISO standards. AATS has established full quality system on personnel, training, sample receipt and handling, testing, quality control and documentation. We provide testing results of high quality, because we have a strong quality system built in our testing facilities.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 16,2024. Portal, Core facility
The Immunohistochemistry Core, a component of the Experimental Pathology Shared Resource, is located in Bellevue Hospital within the NYULMC Department of Pathology''s Anatomic Pathology clinical space. The laboratory serves as an immunohistochemical antibody repository with a catalog of over 900 antibodies. Antibodies are in stock and available for use in the core laboratory for the collection of experimental immunohistochemistry data. The laboratory develops immunohistochemical protocols for new antibodies (commercial or proprietary) that have not been tested in fresh, frozen, fixed human or animal tissues and cells. In addition to performing manual labeling, the laboratory is equipped with two Ventana NEXES and one Discovery automated immunohistochemical staining instruments. The laboratory uses human and animal tissue micro-arrays for validation and employs a wide variety of antigen retrieval methods for protocol development. The core offers tyramide and polymer amplification methods (manual) and single or two color chromogenic immunohistochemistry. The laboratory has also commenced developing protocols and validating antibodies for immunoflorescence in frozen and FFPE tissue samples. The laboratory faculty and staff are available to provide hands-on informal training, as well as guidance and support for the design and execution of experiments involving histopathology and immunohistochemistry of human and animal cells and tissues. In conjunction with the Histopathology Core Laboratory, the Immunohistochemistry Laboratory can also assist investigators with routine and advanced histopathologic services for tissue and cell specimens (including guidance on initial processing steps: grossing/tissue preparation, processing, embedding, paraffin/frozen microtomy) for samples destined for histopathological interpretation and analysis. In addition, we offer extensive options for special and routine histochemical and immunohistochemical labeling of both human and animal model cells and tissues.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 23,2024. With more than 250 physicians and scientists dedicated to cancer care and research, Sylvester is leading the search for a cancer cure. Every day, our physicians and scientists within the cancer center''''s site disease groups and multidisciplinary research programs, are discovering exciting new breakthroughs that are quickly transforming the way cancer patients are diagnosed and treated.
CFG maintains core competencies in genomics, proteomics, bioinformatics, transgenesis and cell and tissue culture. Provides lab space, technological infrastructure, and staff. Provides basic laboratory services to bioscience researchers at companies, universities, and government agencies around world for fee. Works with Commonwealth Biotechnologies, Inc. for projects that need to meet FDA requirements for submission of data in support of new drug applications.
Core serves as a centralized resource for providing expert and timely bioinformatics consulting and data analysis solutions. The core offers services to investigators both within and outside UVA on both grant-funded and chargeback-based projects for management and analysis of large-scale biological datasets produced by high-throughput genomics experiments. The Core's mission is to build and maintain an infrastructure that enables the application of strong bioinformatics analysis with a measurable impact on the ability of UVa investigators to both publish their work and obtain new funding.
The Center of Biomedical Research Excellence (COBRE) in Neuroscience at the University of Vermont (UVM), which was established in 2001 with funding from the National Center for Research Resources of the National Institutes of Health, was created to integrate and expand neuroscience research and training at UVM by building a collaborative intellectual infrastructure, developing cutting-edge shared core facilities, and by providing research funding for neuroscience faculty, especially junior faculty, in multiple colleges. The Neuroscience COBRE supported formation of the university-wide Neuroscience Graduate Program, expanded interdisciplinary neuroscience research, and promoted translational research by increasing the interaction between basic and clinical neuroscientists at UVM.
Interdisciplinary NMR spectroscopy research facility for structural elucidation and study of conformation and dynamics of organic compounds, peptides, oligonucleotides and other small biopolymers.
Established in 1986, the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) was established in 1986. The mission of the NIAMS is to support research into the causes, treatment, and prevention of arthritis and musculoskeletal and skin diseases; the training of basic and clinical scientists to carry out this research; and the dissemination of information on research progress in these diseases. The Institute also conducts and supports basic research on the normal structure and function of bones, joints, muscles, and skin. Basic research involves a wide variety of scientific disciplines, including immunology, genetics, molecular biology, structural biology, biochemistry, physiology, virology, and pharmacology. Clinical research includes rheumatology, orthopaedics, dermatology, metabolic bone diseases, heritable disorders of bone and cartilage, inherited and inflammatory muscle diseases, and sports and rehabilitation medicine.
The Cell Biology and Bioimaging Core (CBBC) provides access to state of the art imaging, analytical, and histological equipment as well as technical expertise and assistance to researchers at the PBRC, LSU''s main campus, and outside the LSU university system.
Executive branch department of the federal government charged with coordinating and supervising all agencies and functions of the government directly related to national security and the United States Armed Forces.
The Blizard Institute is the largest institute of Barts and the London School of Medicine and Dentistry and aims to deliver excellence in all aspects of research, teaching and clinical service
Barts and The London offers international levels of excellence in research and teaching while serving a population of unrivalled diversity. Through partnership with our linked trusts, notably Barts and The London NHS Trust, and our associated University Hospital Trusts _������������_ Homerton, Newham, Whipps Cross and Queen''''s (Romford) the School''''s research and teaching is informed by an exceptionally wide ranging and stimulating clinical environment.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. Preclinical CRO for drug development services including a wide variety of disease model studies as well as PK and toxicity services. Major service areas are: - Preclinical In Vivo Efficacy Testing of compounds in many disease models including inflammatory diseases, cancer and bacterial infection. - Vaccine testing services including vaccine efficacy testing in disease model studies such as arthritis. - Bacterial efficacy studies in mice and rats to determine antibiotic efficacy. - Pharmacokinetics and related in vivo tests. - Our technical staff has a combined 70+ years of experience in drug and vaccine development services for efficacy and safety.
To perform research into cancer is the task of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ). DKFZ is the largest biomedical research institute in Germany and a member of the Helmholtz Association of National Research Centers. In over 70 divisions and research groups, our more than 2,500 employees, of which more than 1,000 are scientists, are investigating the mechanisms of cancer, are identifying cancer risk factors and are trying to find strategies to prevent people from getting cancer.They are developing novel approaches to make tumor diagnosis more precise and treatment of cancer patients more successful.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 15, 2024. Commercial neuroimaging organization that provides services for compound profiling, biostatistics, computed tomography, and data modeling.