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The mission of The Progeria Research Foundation is to discover treatments and the cure for Progeria, and its aging related disorders. Progeria is a rare and fatal genetic disease characterized by an appearance of accelerated aging in children. Without the discovery of new treatments, all children with Progeria will die of heart disease at an average age of 13 years. The Progeria Research Foundation (PRF) was founded in 1999 in response to the complete lack of progress being made to help children with Progeria. We have filled a void, taking these children out of the background where they had been for over 100 years and putting them and Progeria at the forefront of scientific efforts. In just 11.5 years, we have achieved extraordinary progress towards our mission: the Progeria gene discovery in 2003, first-ever clinical drug trials initiated in 2007, extensive global awareness of the disease and PRF''s work, and discovery of critical biological links between Progeria, heart disease and aging we all experience.

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• SciCrunch
• 16 years ago - by Anonymous

Software that allows hierarchical data to be explored with zoomable pie charts.

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• SciCrunch
• 13 years ago - by Anonymous

The InterActive Fly is an online database of Drosophilia development and metazoan evolution. It contains information on biochemical pathways, organs, images, a cis-decoder, and EvoPrinter, a machine that allows users to identify Evolutionarily Resilient DNA Sequences.

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• SciCrunch
• 15 years ago - by Anonymous

Founded in 1966, the School of Graduate Studies is one of four colleges comprising the State University of New York Health Science Center at Brooklyn, and is accredited by the Middle States Association of Colleges and Secondary Schools. The School of Graduate Studies grants the degree of Doctor of Philosophy in three programs: Neural & Behavioral Science, Molecular & Cellular Biology and Biomedical Engineering.

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• SciCrunch
• 15 years ago - submitted by Eddy Kim

Open-access database of antibodies against human proteins developed through collaboration between Antibodypedia AB and the Nature Publishing Group. It aims to provide the scientific community and antibody distributors alike with information on the effectiveness of specific antibodies in specific applications--to help scientists select the right antibody for the right application. Antibodypedia's mission is to promote the functional understanding of the human proteome and expedite analysis of potential biomarkers discovered through clinical efforts. To this end, they have developed an open-access, curated, searchable database containing annotated and scored affinity reagents to aid users in selecting antibodies tailored to specific biological and biomedical assays. They envisage Antibodypedia as a virtual repository of validated antibodies against all human, and ultimately most model-organism, proteins. Such a tool will be exploitable to identify affinity reagents to document protein expression patterns in normal and pathological states and to purify proteins alone and in complex for structural and functional analyses. They hope to promote characterization of the roles and interplay of proteins and complexes in human health and disease. They encourage commercial providers to submit information regarding their inventory of antibodies with links to quality control data. Independent users can submit their own application-specific experimental data using standard validation criteria (supportive or non-supportive) developed with the assistance of an international advisory board recruited from academic research institutions. Users can also comment on specific antibodies without submitting validation data.

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• SciCrunch
• 17 years ago - by Anonymous

Software that provides an integrated solution for the Illumina microarray data analysis.

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• SciCrunch
• 13 years ago - by Anonymous

A high-quality integrated knowledge resource specialized in the immunoglobulins (IG) or antibodies, T cell receptors (TR), major histocompatibility complex (MHC) of human and other vertebrate species, and in the immunoglobulin superfamily (IgSF), MHC superfamily (MhcSF) and related proteins of the immune system (RPI) of vertebrates and invertebrates, serving as the global reference in immunogenetics and immunoinformatics. IMGT provides a common access to sequence, genome and structure Immunogenetics data, based on the concepts of IMGT-ONTOLOGY and on the IMGT Scientific chart rules. IMGT works in close collaboration with EBI (Europe), DDBJ (Japan) and NCBI (USA). IMGT consists of sequence databases, genome database, structure database, and monoclonal antibodies database, Web resources and interactive tools.

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• SciCrunch
• 16 years ago - by Anonymous

A software package to do meta-analysis which works in a spreadsheet interface and also provides forest plots, which are useful for visualizing between-study heterogeneity.

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• SciCrunch
• 13 years ago - by Anonymous

For each developmental stage (using the staging system defined by Theiler), the Mouse Anatomical Dictionary organizes the terms hierarchically from body region or system to tissue to tissue substructure. Modeling the anatomy hierarchically makes it possible to record expression results from assays with differing spatial resolution in a consistent and integrated manner. The Mouse Anatomical Dictionary Browser lets you navigate the extensive dictionary hierarchies for the different developmental stages, locate specific anatomical structures within those hierarchies, and see the expression results associated with those structures. Stages 1 through 26 (embryonic development) are being developed at the Department of Biomedical Sciences, University of Edinburgh, Scotland and the MRC Human Genetics Unit, Edinburgh, as part of The Mouse Atlas and 3D Graphical Gene Expression Database Project. Stage 28 (postnatal mouse) is being developed by the Gene Expression Database Project at The Jackson Laboratory.

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• SciCrunch
• 16 years ago - by Anonymous

An independent, not-for-profit organization, The Joint Commission accredits and certifies more than 19,000 health care organizations and programs in the United States. Joint Commission accreditation and certification is recognized nationwide as a symbol of quality that reflects an organization''s commitment to meeting certain performance standards. The Joint Commission is the nation''s oldest and largest standards-setting and accrediting body in health care. To earn and maintain The Joint Commission''s Gold Seal of Approval, an organization must undergo an on-site survey by a Joint Commission survey team at least every three years. (Laboratories must be surveyed every two years.) Our Mission: To continuously improve health care for the public, in collaboration with other stakeholders, by evaluating health care organizations and inspiring them to excel in providing safe and effective care of the highest quality and value. Vision Statement: All people always experience the safest, highest quality, best-value health care across all settings.

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• SciCrunch
• 16 years ago - by Anonymous

A web-based application designed with an easy-to-use interface to facilitate the high-throughput assessment and prioritization of genes and missense alterations important for cancer tumorigenesis.

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• SciCrunch
• 13 years ago - by Anonymous

The Institute of Molecular and Cell Biology (IMCB) was established in 1987 at the National University of Singapore (NUS) before becoming an autonomous research institute (RI) of A*STAR. Its mission is to develop and foster a vibrant research culture for cutting-edge basic biomedical sciences and for training high-quality Ph.D. students for the flourishing biotechnology and pharmaceutical industries in Singapore. Funded primarily by the Biomedical Research Council (BMRC) of A*STAR, IMCB now boasts about 30 core research labs and 8 core facility units consisting of over 300 research scientists in total. IMCB''s research activities focus on six major fields: Cell Biology, Developmental Biology, Structural Biology, Infectious Diseases, Cancer Biology and Translational Research with core strengths in cell cycling, cell signalling, cell death, cell motility and protein trafficking. IMCB continues to strive for excellence in biomedical R&D to see the vision of Singapore being a world class hub for the Biomedical Sciences in Asia and beyond. IMCB''s achievements include being part of the international consortium that successfully sequenced the entire pufferfish (Fugu rubripes) in 2002. IMCB was awarded the Nikkei Prize 2000 for Technological Innovation in recognition of its growth into a leading international research centre and its collaboration with industry and research institutes worldwide. IMCB continues to publish in renowned international journals, with more than 1300 publications to its credit since 1987.

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• SciCrunch
• 16 years ago - submitted by Christie Wang

NBRP-Rat was established to overcome limitations associated with properly utilizing existing rat resources. The collection of existing strains and genetic sub strains, phenotypic and genotypic characterization, cryopreservation of embryos, distribution of the collected rat strains, and a publicly accessible database of all assembled data are the major goals of this project. Once achieved, this unique database including the unique rat strains will become a powerful tool for biomedical research. A catalog of comparable, standardized and well characterized rat strains will lead to new and more precise research topics as well as it will facilitate biomedical sciences, drug discovery, advanced chemical research, and contributes to life sciences worldwide. As mentioned before, the major goals of NBRP-Rat are the collection, preservation and supply of rat strains. The repository includes strains from Japan and abroad, spontaneous mutants, congenic and recombinant strains as well as transgenic and mutagenized rats. Deposited rat strains are not only conserved as cryopreserved embryos and sperm. Many reference and frequently used rat strains are also maintained as living animals under SPF conditions. Furthermore, NBRP-rat provides a unique database on various rat strain phenotypes accompanied with basic genetic information. This allows scientists the selection of standardized and research specific strains. The animals themselves are provided free of charge to the research community (except for shipping costs). Sponsors: This project is one part of the National BioResource Projects (NBRP) in Japan for more than 20 species including animals, plants, microbes, tissues and DNAs. It is founded by the Japanese Ministry of Education, Culture, Sports, Science and Technology (Monkasho) and started in 2002.

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• SciCrunch
• 17 years ago - by Anonymous

Integrated database resource consisting of 16 main databases, broadly categorized into systems information, genomic information, and chemical information. In particular, gene catalogs in completely sequenced genomes are linked to higher-level systemic functions of cell, organism, and ecosystem. Analysis tools are also available. KEGG may be used as reference knowledge base for biological interpretation of large-scale datasets generated by sequencing and other high-throughput experimental technologies.

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• SciCrunch
• 16 years ago - by Anonymous

Whole genome secondary analysis on Illumina sequencing platforms.

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• SciCrunch
• 13 years ago - by Anonymous

A software tool for performing rapid local alignment searches in amino acid or nucleotide sequence databases.

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• SciCrunch
• 13 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE.Documented on April 14,2022. Database of comprehensive information on the approximately 600 prokaryote species that are present in the human oral cavity. The majority of these species are uncultivated and unnamed, recognized primarily by their 16S rRNA sequences. The HOMD presents a provisional naming scheme for the currently unnamed species so that strain, clone, and probe data from any laboratory can be directly linked to a stably named reference entity. The HOMD links sequence data with phenotypic, phylogenetic, clinical, and bibliographic information. Full and partial oral bacterial genome sequences determined as part of this project and the Human Microbiome Project, are being added to the HOMD as they become available. HOMD offers easy to use tools for viewing all publicly available oral bacterial genomes. Data is also downloadable.

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• SciCrunch
• 16 years ago - by Anonymous

Software for strand specific peak-pair calling in ChIP-exo replicates.

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• SciCrunch
• 13 years ago - by Anonymous

A fully scalable online pre-processing algorithm for short oligonucleotide microarray atlases.

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• SciCrunch
• 13 years ago - by Anonymous

Free and open access to data about development in countries around the globe.

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• SciCrunch
• 13 years ago - by Anonymous