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The Department of Pharmacology and Physiology consists of faculty, fellows and students who are dedicated to cutting-edge scientific research, in order to work towards a better understanding of how the human body functions and to alleviate human diseases. The faculty is composed of distinguished scientists who are international leaders in the fields of cell signaling and signal transduction, neurodegenerative diseases and mechanisms of cell death, cardiovascular diseases and ion channels, drugs of abuse and mechanisms of addiction, and integrative biomedical sciences. The department promotes a strong training program for both graduate students and post-doctoral fellows, and many of our graduates have gone on to become leaders in academia, industry and government. The University of Rochester Medical Center is now in the process of unprecedented growth, which includes the opening of two new research buildings and the establishment of over fifty new research laboratories. The Department is enthusiastic about being a part of that growth in the research enterprise, as we aim to be one of the finest medical centers in the world.

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• SciCrunch
• 17 years ago - by Anonymous

Independent agency of the U.S. federal government that administers Social Security, a social insurance program consisting of retirement, disability, and survivor benefits.

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• SciCrunch
• 16 years ago - submitted by Andrea Stagg

The mission of the National Institute of Dental and Craniofacial Research (NIDCR) is to improve oral, dental and craniofacial health through research, research training, and the dissemination of health information. We accomplish our mission by: * Performing and supporting basic and clinical research; * Conducting and funding research training and career development programs to ensure an adequate number of talented, well-prepared and diverse investigators; * Coordinating and assisting relevant research and research-related activities among all sectors of the research community; * Promoting the timely transfer of knowledge gained from research and its implications for health to the public, health professionals, researchers, and policy-makers.

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• SciCrunch
• 14 years ago - submitted by Andrea Stagg

A plugin for the open-source MATLAB toolbox EEGLAB developed with the goal to facilitate integrated analyses of electrophysiological and oculomotor data. The plugin parses, imports, and synchronizes simultaneously recorded eye tracking data and adds it as extra channels to the EEG. Saccades and fixations can be imported from the eye tracking raw data or detected with an adaptive velocity-based algorithm. Eye movements are then added as new time-locking events to EEGLAB's event structure, allowing easy saccade- and fixation-related EEG analysis (e.g., fixation-related potentials, FRPs). Alternatively, EEG data can be aligned to stimulus onsets and analyzed according to oculomotor behavior (e.g. pupil size, microsaccades) in a given trial. Saccade-related ICA components can be objectively identified based on their covariance with the electrically independent eye tracker. All functions can be accessed via EEGLAB's GUI or called from the command line.

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• SciCrunch
• 13 years ago - by Anonymous

Resource out of service. Documented on February 24,2021.

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• SciCrunch
• 17 years ago - by Anonymous

News source including the entire bioproduct life cycle from early-stage R&D, to applied research including omics, biomarkers, as well as diagnostics, to bioprocessing and commercialization.

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• SciCrunch
• 13 years ago - by Anonymous

A non-profit organization of scientists and healthcare professionals committed to preventing and curing liver disease, which runs three journals and an annual meeting. Its mission is to Advance the Science and Practice of Hepatology, Liver Transplantation and Hepatobiliary Surgery, Thereby Promoting Liver Health and Optimal Care of Patients with Liver and Biliary Tract Diseases. AASLD was founded in 1950 by a small group of leading liver specialists (including Hans Popper, Leon Schiff, Fred Hoffbauer, Cecil Watson, Jesse Bollman, and Sheila Sherlock, to name a few) to bring together those who had contributed to the field of hepatology. AASLD has grown to an international society responsible for all aspects of hepatology, and our annual meeting, The Liver Meeting, has grown in attendance from 12 to over 7,000 physicians, surgeons, researchers, and allied health professionals from around the world. AASLD sponsors two to four Single Topic Conferences each year in clinical, basic, hepatitis, or pediatric hepatology. Our two monthly journals, HEPATOLOGY and Liver Transplantation, provide the latest research findings for hepatology and surgery of the liver. AASLD''s membership includes ALL professionals dedicated to hepatobiliary discoveries and patient care. Mentoring, the sharing of knowledge, and dedication to professional growth and development are among the core values of AASLD and its members.

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• SciCrunch
• 15 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on March 12,2025. The AIDSinfo Drug Database provides fact sheets on HIV/AIDS related drugs. The fact sheets describe the drug''s use, pharmacology, side effects, and other information. The database includes: -Approved and investigational HIV/AIDS related drugs -Three versions of each fact sheet: patient, health professional, and Spanish. AIDSinfo is a 100% federally funded U.S. Department of Health and Human Services (DHHS) project that offers the latest federally approved information on HIV/AIDS clinical research, treatment and prevention, and medical practice guidelines for people living with HIV/AIDS, their families and friends, health care providers, scientists, and researchers. Sponsors: -National Institutes of Health (NIH) Office of AIDS Research National Institute of Allergy and Infectious Diseases (NIAID) National Library of Medicine (NLM) -Health Resources and Services Administration (HRSA) -Centers for Disease Control and Prevention (CDC) -Centers for Medicare and Medicaid Services (CMS)

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• SciCrunch
• 17 years ago - by Anonymous

Software package that provides functions to identify genomic regions of interest based on segmented copy number data from multiple samples.

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• SciCrunch
• 13 years ago - by Anonymous

The Department of Health is committed to improving the quality and convenience of care provided by the NHS and social services. Its work includes setting national standards, shaping the direction of health and social care services and promoting healthier living. Funding. The Association of Medical Research Charities (AMRC) was founded to further medical research in the United Kingdom, and develop the effectiveness of those charities for which medical research is a major activity. There are currently 114 charities including the world''s largest charity, the Wellcome Trust, within the Association of Medical Research Charities, covering a wide range of diseases. Their combined expenditure on medical research is approximatelly 800m per annum

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• SciCrunch
• 14 years ago - by Anonymous

Accurate error-correction of amplicon pyrosequences.

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• SciCrunch
• 13 years ago - by Anonymous

Center with mission to conduct and support medical research and research training and to disseminate science-based information on diabetes and other endocrine and metabolic diseases. The NIDDK supports a wide range of medical research through grants to universities and other medical research institutions across the country.

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• SciCrunch
• 16 years ago - submitted by Stephen Larson

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 23,2023. A graphical program to trace anatomical features in 3D image volumes. This tools is built upon the NA-MIC toolkit. The tool is fully compatible with Slicer3, and integrates the Slicer3 theme.

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• SciCrunch
• 13 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE,documented on January,18, 2022. The objectives of the BBSRC IGF funding that started FlyChip were to establish a genomics infrastructure that would provide UK Drosophila researchers access to these emerging technologies, thereby maintaining the internationally recognised research profile the UK fly community enjoys. Via the IGF initiative, and with other funding, we have developed core genomics resources for the UK Drosophila community and we continue to develop these resources in a national and international context. As the facility has developed we are providing access to genomics technologies for researchers working with other organisms. Our Specific objective are: To drive the development of genomics resources and techniques and make these widely available to the broader research community. It is our aim to implement new omics techniques and make them available to the community, both through our facility and also through transfer of expertise to other UK research groups. Provide access to state-of-the-art microarray platforms for expression profiling and other genomics applications. Develop methodologies, especially in terms of quality control, normalisation, quantification and data analysis, that will be broadly applicable to the design and implementation of genomics experiments in metazoans. As a complex eukaryote with a compact genome, the Drosophila model is ideally suited to such a role. To expand the scope of the genomics resources to enable the community to encompass the use of whole genome arrays for expression profiling, transcription factor binding studies and chromatin structure studies. To develop a more cohesive interaction with members of the community who require access to genomics tools. We wish offer a flexible and interactive service for UK researchers, accommodating those who need access to reagents to perform their own genomics studies or hosting researchers within the facility for more complex studies. Utilise Drosophila as a model for establishing an effective metazoan systems biology platform. To form multidisciplinary collaborations aimed at developing new genomics techniques and informatics methods. Take a proactive role in the creation of international public genomics resources that benefit not only the UK research community, but also, through the development of international standards and resources, the world wide fly community. Overview This microarray format is no longer available. Each microarray contains 18,240 elements (or ''spots''). This array is composed of transcript-specific oligonucleotides and controls developed by the International Drosophila Array Consortium (INDAC). These controls include spikes, i.e., probes complementatary to targets in A. thaliana, spotting buffer, and probe degradation. Empty wells in the INDAC set are also printed. The spot layout is randomised to facilitate correction of systematic biases. The spots have an estimated mean diameter of 90-120 m. Gene Expression Omnibus (GEO) accession: GPL5016 Materials and Equipment FL002 microarrays were printed using the Genetix Qarray2 contact-printing instrument and 48 Genetix aQu75 split-pins on FMB PowerMatrix slides. Probe DNA was dissolved in 150 mM NaPO4. The printed oligo-set consisted of: A gene-specific Drosophila melanogaster 70mer long oligonucleotide set prepared in conjunction with INDAC (INDAC) Gene-specific Arabidopsis thaliana 70mer long oligonucleotide spike controls developed by FlyChip (protocols) and prepared in conjunction with INDAC (INDAC) 70mer probe degradation long oligonucleotide set prepared in conjunction with INDAC (INDAC) Sponsor. DH is funded by a Grand Challenges in Global Health grant to a consortium led by Austin Burt.

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• SciCrunch
• 17 years ago - by Anonymous

Public research university located in Ghent, Belgium. One of the biggest Flemish universities.

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• SciCrunch
• 17 years ago - submitted by Timothy Tsui

Software package that includes quality control metrics, a selection of normalization methods and novel methods to identify differentially methylated regions and to highlight copy number aberrations.

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• SciCrunch
• 13 years ago - by Anonymous

An error correction module for Illumina sequencing reads, which is based on the k-mer spectrum approach.

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• SciCrunch
• 13 years ago - by Anonymous

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• SciCrunch
• 17 years ago - submitted by Andrea Stagg

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• SciCrunch
• 15 years ago - submitted by Andrea Stagg

NIGMS supports basic biomedical research that is not targeted to specific diseases. NIGMS funds studies on genes, proteins, and cells, as well as on fundamental processes like communication within and between cells, how our bodies use energy, and how we respond to medicines. The results of this research increase our understanding of life and lay the foundation for advances in disease diagnosis, treatment, and prevention. NIGMS also supports research training programs that produce the next generation of biomedical scientists, and it has special programs to encourage underrepresented minorities to pursue biomedical research careers. The National Institute of General Medical Sciences (NIGMS) primarily supports research that lays the foundation for advances in disease diagnosis, treatment, and prevention. The Institute's research training programs help provide the next generation of scientists. Each year, NIGMS-supported scientists make many advances in understanding fundamental life processes. In the course of answering basic research questions, these investigators increase our knowledge about the mechanisms and pathways involved in certain diseases. Institute grantees also develop important new tools and techniques, some of which have medical applications. In recognition of the significance of their work, a number of NIGMS grantees have received the Nobel Prize and other high scientific honors. At any given time, NIGMS supports approximately 4,700 research grants—approximately 11 percent of the grants funded by NIH as a whole. NIGMS also supports approximately 26 percent of the trainees who receive assistance from NIH. NIGMS also supports approximately 25% of the trainees who receive assistance from NIH. The Institute places great emphasis on supporting investigator-initiated research grants. It funds a limited number of research center grants in selected fields, including structural genomics, trauma and burn research, and systems biology. In addition, NIGMS supports several important scientific resources, including the NIGMS Human Genetic Cell Repository and the Protein Data Bank.

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• SciCrunch
• 16 years ago - submitted by Stephen Larson