Curator Dashboard

Software and server that performs intelligent design of oligonucleotides for DNA microarrays.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Software for selecting probes in heterogenous transcriptional sets.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 5,2023. Integrated analysis of cross-platform microarray and pathway data.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Software providing a fast scatterplot smoother suitable for microarray normalization based on B-splines with second-order difference penalty. Functions for microarray normalization of single-colour data i.e. Affymetrix/Illumina and two-colour data supplied as marray MarrayRaw-objects or limma RGList-objects are available.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

A map/reduce based application for mapping short reads generated by the next-generation sequencing machines.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Public research university located primarily in Brisbane, the capital city of the Australian state of Queensland. Founded in 1909 by the Queensland parliament, UQ is one of the six sandstone universities, an informal designation of the oldest university in each state.

• Organization
• SciCrunch
• 18 years ago - submitted by Stephen Larson

An integrated application software tool for miRNA identification from RNA sequencing data.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

A not-for-profit alliance of 23 cancer centers devoted to patient care, research, and education, is dedicated to improving the quality, effectiveness, and efficiency of cancer care so that patients can live better lives. Through the leadership and expertise of clinical professionals at NCCN Member Institutions, NCCN develops resources that present valuable information to the numerous stakeholders in the health care delivery system. As the arbiter of cancer care, NCCN promotes the importance of continuous quality improvement and recognizes the significance of creating clinical practice guidelines appropriate for use by patients, clinicians, and other health care decision-makers.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Software package that uses hidden Ising models to identify enriched genomic regions in ChIP-chip data.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

An international team that works on a fee-for-service basis with policy makers and clinicians around the world to promote evidence-based decision making in healthcare.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

NIH Project to generate resources to characterize the human microbiota and to analyze its role in human health and disease at several different sites on the human body, including nasal passages, oral cavities, skin, gastrointestinal tract, and urogenital tract using metagenomic and traditional approach to genomic DNA sequencing studies.HMP was supported by the Common Fund from 2007 to 2016.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

Database for molecular typing and microbial genome diversity.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Software tool that screens DNA sequences for interspersed repeats and low complexity DNA sequences. The output of the program is a detailed annotation of the repeats that are present in the query sequence as well as a modified version of the query sequence in which all the annotated repeats have been masked (default: replaced by Ns). Currently over 56% of human genomic sequence is identified and masked by the program. Sequence comparisons in RepeatMasker are performed by one of several popular search engines including nhmmer, cross_match, ABBlast/WUBlast, RMBlast and Decypher. RepeatMasker makes use of curated libraries of repeats and currently supports Dfam ( profile HMM library ) and RepBase ( consensus sequence library ).

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Community model organism database for laboratory mouse and authoritative source for phenotype and functional annotations of mouse genes. MGD includes complete catalog of mouse genes and genome features with integrated access to genetic, genomic and phenotypic information, all serving to further the use of the mouse as a model system for studying human biology and disease. MGD is a major component of the Mouse Genome Informatics.Contains standardized descriptions of mouse phenotypes, associations between mouse models and human genetic diseases, extensive integration of DNA and protein sequence data, normalized representation of genome and genome variant information. Data are obtained and integrated via manual curation of the biomedical literature, direct contributions from individual investigators and downloads from major informatics resource centers. MGD collaborates with the bioinformatics community on the development and use of biomedical ontologies such as the Gene Ontology (GO) and the Mammalian Phenotype (MP) Ontology.

• Resource
• SciCrunch
• 16 years ago - by Anonymous

This resource provides detailed information about the major research themes in the Institute of Neuroscience at the New Castle University. The major research themes of this department include: * Behavior, Psychology and Cognitive Neurosciences * Developmental Neuroscience, Aging and Neurodegeneration * Neural Circuits and Neuroimaging * Neurology, Neurosurgery, and Motor Control * Neuropharmacology and Neurotechnology * Psychiatric Neurosciences * Visual, Auditory and Sensory Neuroscience

• Resource
• SciCrunch
• 17 years ago - by Anonymous

A multi-center and multi-disciplinary study designed to dramatically increase understanding of chronic traumatic encephalopathy (CTE) and other late effects of traumatic brain injury (TBI). Overlapping clinical features, postmortem pathologies and patterns of involvement exist in TBI, CTE, and Alzheimer''s disease pose challenges to accurate diagnosis. Premortem diagnosis of CTE is currently impossible. The neuropathological consequences of single mild or moderate-severe TBI and its relationship with CTE and known dementias are unclear. The proposed project will leverage extensive resources from an ongoing population-based prospective cohort study of brain aging (Adult Changes in Thought; ACT, n=2,305) which includes excellent medical, behavioral, and genetic characterization of a cohort (20% of whom have a history of mild-moderate TBI) in addition to state-of-the-art neuropathology workup upon death. Neuropathological study of TBI effects can begin immediately in the existing ACT autopsy sample (n=489, 20% with TBI exposure). Additional cohorts of TBI- exposed individuals will come from the Brain Injury Research Center at Mount Sinai (n=150 individuals with moderate-severe TBI), the University of Texas Southwestern (n=50 retired boxers with repetitive TBI exposure), and the National Football League (n=76 retired players with repetitive TBI exposure). All participants in the proposed study (ACT and other sites) will undergo uniform harmonized neurobehavioral assessment (chosen to maximize correspondence with existing large-scale TBI and dementia studies), MRI scan, and genomic analysis. Those individuals who expire during the course of the study will undergo ex-vivo neuroimaging and extensive neuropathological exam using state-of-the-art techniques (such as Histelide) designed to quantify tau and A�� in whole brain specimens. Only by examining postmortem pathology in a sample of individuals with varying levels of TBI exposure who are well characterized during life (as proposed herein) can postmortem pathology facilitate identification of in-vivo biomarkers that can act as diagnostic tools. This project represents the most systematic and scientifically rigorous effort to date to develop a more complete understanding of the long-term clinical and neuropathological sequelae of single and multiple TBI.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

A list of major inbred mouse strains from the Jackson laboratories. This list is not being actively maintained (found on Nov 27, 2013).

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Database with curated datasets of mitochondrial DNA (mtDNA) rearrangements. Users may submit new mtDNA rearrangements.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

A phylogenetic tree of global human mitochondrial DNA variation, based on both coding- and control-region mutations, and including haplogroup nomenclature.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Software providing methods for segmenting, normalising and processing aCGH data; including plotting functions for visualising raw and segmented data for individual and multiple arrays.

• Resource
• SciCrunch
• 13 years ago - by Anonymous