We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Software R package for Affymetrix Human Genome U133 Plus 2.0 Array annotation data.
Cytokine Multiplex Assay Kits allow researchers to simultaneously detect the levels of multiple cytokines in a single sample. This is particularly useful for identifying the wide array of changes that can be associated with different pathological conditions.
This instrument is precision liquid handling instrument that enables non-contact, nanoliter-to-microliter scale dispensing of small molecules, biologics, or other reagents directly into assay plates for high-throughput drug screening and dose-response studies.
Arrayer produces high quality microarrays of DNA, proteins, cell lysates and variety of other samples using its proprietary soft touch deposition technology.
Core features several high- and low-resolution mass spectrometers, coupled with liquid and gas chromatographs, as well as an ICP-MS. In addition, we have liquid chromatographs available that operate with other types of detectors. The laboratory collaborates with activities carried out at the Institute of Chemistry, in external academic sectors, and also within private enterprise.
High-speed, high-resolution light sheet microscope designed for imaging large, cleared tissue samples. Utilizes patented axially-swept light sheet technology to achieve uniform axial resolution across the entire sample, enabling rapid volumetric imaging. System is particularly well-suited for imaging cleared tissues, including whole organs and even entire juvenile mice, with options for both aqueous and organic clearing methods. Light sheet imaging for rapid volumetric acquisition of intact samples.
Light sheet fluorescence microscope designed for high-resolution, three-dimensional imaging of large, cleared, and fluorescently labeled biological samples. It excels at visualizing entire biological systems like organs, embryos, or even small animals with cellular resolution, making it suitable for studying complex biological structures and processes.
Facility provides access to imaging equipment and analysis tools. It houses widefield, laser scanning confocal, spinning disk confocal, multi-photon, light-sheet, and super-resolution microscopes, along with two transmission electron microscopes and high-content screener. Offers centralized workstation for image processing, high-performance computing capabilities, and data storage. Provides access to several commercial software programs for image analysis and data quantification. Services include consultations for sample preparation, training on the microscopes, full imaging support, and assistance with analysis strategies. Provides several services related to transmission electron microscopy: tissue/cell processing, image acquisition training or assistance, and image analysis support. CoRE scientists can collaborate with investigators to develop novel imaging methods and analysis approaches.
NITRC-IR Test is for invited individuals to test the NITRC-Image Repository Beta functionality and provide the NITRC team feedback feed before making this functionality fully public.
Software accurate read-based phasing tool that integrates multiple methodologies to enhance phasing accuracy. Used to efficiently phase genomic data by linking sequencing reads across heterozygous sites, extending haplotype blocks, and incorporating pre-phased data when available. Read-based phasing algorithm with integrated multi-method support for enhanced accuracy.
Multiphoton imaging system for deep imaging in biological tissue. For advanced applications,dual-wavelength excitation extending to 1300 nm is available. Independent control of visible or multiphoton laser light stimulation and ability to synchronize with patch clamp data are also possible. Multiple configurations are available.
Icahn School of Medicine at Mount Sinai Microscopy and Advanced Bioimaging Core Facility imaging system offers stable imaging conditions, especially crucial for high magnification and time-dependent studies. Z2m model is optimized for materials science applications. It is often used for tasks like 3D subsurface studies of transparent ceramics, metallography, corrosion studies, analysis of thin film uniformity, and inclusion analysis in metals. It is particularly well-suited for situations that require motorized stage to handle large samples.
Software pipeline for lightweight screening of Eukaryotic genomes and transcriptomes for recent HGT. Used to quickly screen for transferred genes.
Software phylogenomic pipeline designed to analyze proteomes from diverse organisms and inferring orthology, gene-family trees, and species tree. Highly parallelized and computationally efficient phylogenomic workflow that infers gene families, gene family trees, species trees, and gene family evolutionar history. Efficiently performs phylogenetic comparisons at any evolutionary scale.
Software pipeline to build similarity maps of protein space. Identifies proteins related to query protein using sequence- and structure-based searches, compares all protein structures, and creates navigable map that can be used to look at protein relationships and make hypotheses about function.
Software R package that supports different types of gene set enrichment workflows. Offers multiple enrichment, visualization, and sharing methods in addition to novel features such as hierarchical geneset analysis and built-in markdown reporting.
Icahn School of Medicine at Mount Sinai Microscopy and Advanced Bioimaging Core Leica confocal imaging system designed to maximize number of probes and photon collection sensitivity for wide range of applications, including fixed and live samples
Icahn School of Medicine at Mount Sinai Microscopy and Advanced Bioimaging Core Leica TCS SP8 system located in Icahn Building is high precision confocal microscope for live cell imaging in multicolor. Advanced confocal inverted imaging platform for fixed- and live-cell studies. This system features seven laser excitation lines; motorized stage for multi-position imaging; advanced detection system for spectral unmixing; and full incubation setup for long-term research.
Icahn School of Medicine at Mount Sinai Microscopy and Advanced Bioimaging Core Leica TCS SP8 system is high precision confocal microscope with Acousto-Optical Beam Splitter that allows for flexible control of the excitation and emission light paths.