Curator Dashboard

An Antibody supplier

• Resource
• SciCrunch
• 14 years ago - by Anonymous

An Antibody supplier

• Resource
• SciCrunch
• 14 years ago - by Anonymous

An Antibody supplier.

• Resource
• SciCrunch
• 14 years ago - by Anonymous

Original provider of rabbit monoclonal antibodies. Important Note for Epitomics Customers in the U.S.: As of Jan. 28, 2013, orders for Epitomics products will now be handled directly by Abcam.

• Resource
• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 17, 2013. A specialized database for mouse heart and calcium signaling toolkit genes. It contains the functional gene modules pre-calculated from the microarray data compendium using various algorithms for genetic network analyses. The Heart and Calcium functional Network (HCNet) database is a collection of functional gene clusters calculated from microarray data compendium obtained from the Korea Systems Biology Initiative and from the publicly available GEO database. It was designed to assist experimentalists especially in the field of cardiac and calcium signaling research to detect potential network motifs and gene clusters that are functionally related or co-regulated by common transcription factors. Genes of defined numbers are classified into two categories, 1) heart-specific genes and 2) heart-specific genes plus calcium signaling toolkit-genes.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

A compilation of E. coli mRNA promoter sequences. It includes documentation on the location of experimentally identified mRNA transcriptional start sites on the E. coli chromosome, as well as the actual sequences in the promoter region. The database is currently updated as of July 2000 and includes 471 entries.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

Fast error free and transparent compression (>2x) of image data on disk with NKI private or JPEG compression. A database browser and slice viewer integrated in the PACS system with options for: viewing DICOM header, creating BMP files (ideal for slides), sending selected images, printing, database fix tools such as changing patient IDs, deleting and anonymizing studies and series, and splitting and merging series. Uses drag and drop to load DICOM and HL7 files. A simple query/move user interface for diagnostic purposes, to improve your knowledge of DICOM, and to grab missing data from another server. Elementary DICOM print server and client - prints to the default printer. Correct display of JPEG and RLE compressed images in browser. Flexible configuration of JPEG and NKI private compression with optional (de)compression of incoming, dropped, transmitted and archived files. The JPEG compression is done using executables from the OFFIS DICOM toolkit (DCMTK version 3.5.4), developed by Kuratorium OFFIS e.V. A simple DICOM Modality Worklist implementation with HL7 import with configurable translation. A CGI WEB interface with several possible viewers (especially important for the Linux version without a GUI). The server can act as an advanced scriptable DICOM image forwarder and/or DICOM image cache. The server integrates an advanced DICOM viewer based on K-PAC DICOM training and testing Demonstration and research image archives Image format conversion from a scanner with DICOM network access DICOM image viewing and slide making DICOM image selection, (limited) editing, and splitting and merging of series Advanced scriptable image modification, filtering, forwarding and conversion DICOM caching and archive merging DICOM web access for viewing and data management (scriptable)

• Resource
• SciCrunch
• 17 years ago - by Anonymous

Software application for linkage disequilibrium mapping based on ancestral founder haplotypes. Method uses haplotype data from general pedigrees. (entry from Genetic Analysis Software)

• Resource
• SciCrunch
• 14 years ago - by Anonymous

This site has been developed by Kazusa DNA Research Institute for the purpose of offering the science community the analyzed sequence data produced by a multi-national Arabidopsis genome sequencing project coordinated by the Arabidopsis Genome Initiatives (AGI). The aim of this service is to enable users to browse the annotated sequence data produced by all the sequencing teams of AGI through an user-friendly graphic display system and search engines. Gene structures proposed on the annotated sequences as well as those predicted by computer programs are presented and each graphic item has a hyperlink to detailed information of the corresponding area. The nucleotide sequence data deposited in GenBank by AGI was downloaded, re-computer-analyzed at Kazusa and parsed results are displayed graphically.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

A helper program to automate the tedious process of the creation of input files from genotype data of genome-wide scans (entry from Genetic Analysis Software)

• Resource
• SciCrunch
• 14 years ago - by Anonymous

THe dQSNP database accumulates and presents experimental data of sequences and allele frequencies of SNPs in promoter regions. The regions studied here were mainly 1.0 kb upstream and 0.2 kb downstream of transcriptional start regions (TSS), which have been defined as the 5'' end of full length cDNA, obtained from the database of transcription start sites. Users can search dbQSNP records by Blast-search against STS sequences in this database, by key word or by chromosomal location.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

Welcome to Michael Eisens lab in the Howard Hughes Medical Institute (HHMI) at University of California at Berkeley (UCB) and the Lawrence Berkeley National Lab (LBNL). We are part of the Department of Molecular and Cell Biology of UCB and the Genomics Division of LBNL, and the. We are located in Stanley Hall on the Berkeley campus.Our lab applies computational and experimental genomic approaches to study how genome sequences specify organismal form and function. We are particularly interested in the regulation of gene expression, and focus on how the information that specifies when and where genes are expressed is encoded in genome sequences, the role that regulated gene expression plays in animal development and the response of microbes to their environments, and how variation in and evolution of gene expression contributes to phenotypic variation and the remarkable diversity of life on Earth. This site contains a more detailed description of our research projects, an introduction to members of the lab, reprints of all of our publications, free downloadable and web-based software. Sponsor. Experimental work described here was supported by a Howard Hughes Medical Institute Investigator award to MBE and by National Institutes of Health (NIH) grant GM704403 to MBE and MDB. Computational analyses were supported in by NIH grant HG002779 to MBE. Work at Lawrence Berkeley National Laboratory was conducted under Department of Energy contract DE-AC02-05CH11231. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

Software to process fluorescent images of microarrays.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Software for analysis and visualization of gene expression and SNP microarrays.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Software R package. Methods for Cluster analysis. Performs variety of types of cluster analysis and other types of processing on large microarray datasets.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Software for analysis and visualization of gene expression and SNP microarrays.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Software to graphically browse results of clustering and other analyses from Cluster.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Not yet vetted by NIF curator

• Resource
• SciCrunch
• 16 years ago - by Anonymous

A database for facilitating the search for drug Absorption, Distribution, Metabolism, Excretion (ADME) associated proteins. It contains information about known drug ADME associated proteins, functions, similarities, substrates / ligands, tissue distributions, and other properties of the targets. Associated references are also included. Drug absorption, distribution, metabolism and excretion (ADME) often involve interaction of a drug with specific proteins. Knowledge about these ADME-associated proteins is important in facilitating the study of the molecular mechanism of disposition and individual response as well as therapeutic action of drugs. It is also useful in the development and testing of pharmacokinetics prediction tools. Several databases describing specific classes of ADME-associated proteins have appeared. A new database, ADME-associated proteins (ADME-AP), is introduced to provide comprehensive information about all classes of ADME-associated proteins described in the literature including physiological function of each protein, pharmacokinetic effect, ADME classification, direction and driving force of disposition, location and tissue distribution, substrates, synonyms, gene name and protein availability in other species. Cross-links to other databases are also provided to facilitate the access of information about the sequence, 3D structure, function, polymorphisms, genetic disorders, nomenclature, ligand binding properties and related literatures of each protein. ADME-AP currently contains entries for 321 proteins and 964 substrates. ADME Class Based on their respective role of pharmacokinetics, ADME-associated proteins can be classified into four categories: A: This Category includes proteins involved in the absorption or re-absorption of drugs into systemic system. D: This category includes proteins responsible for facilitating the distribution of drugs from the systemic system to the target sites or away from the target sites back to the systemic system. Certain plasma proteins and intracellular binding proteins may alter free drug concentration by acting as drug storage depot. These proteins thus play a regulatory role in drug distribution and they are thus included in Category D. Based on their role in drug distribution, proteins in this category can be further divided into three groups D1, D2, and D3. The first group D1 includes transporters capable of transporting chemicals across membranes of various tissue barriers from the systemic system into the target sites. Blood-brain barrier and placenta barrier are examples of tissue barrier. Proteins in the second group D2 are responsible for transporting drugs back into the systemic system. Proteins in the third group D3 mainly function as drug storage depot. These include ligand binding proteins in plasma and intracellular proteins. M: Proteins in category M are drug-metabolizing enzymes. These enzymes can be further divided into two separate groups M1 and M2, according to whether the corresponding enzymatic reaction is phase I or phase II. E: This category E includes proteins that enable the excretion or presystemic elimination of drugs. Some proteins belong to more than one category: e.g. P-glycoprotein both limits intestinal absorption and excludes drugs from the brain back to the blood. It thus belongs to both Category E and D. For those proteins capable of transporting natural substrates without literature report of interaction with a drug, a postfix potential is attached to their respective classification to indicate that their specific role in ADME is yet to be confirmed. Use of ADME-AP for commercial purposes is not allowed.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

A dataset generated longitudinal study that aims to explain the relationship between age and changes in the sense of control over one''''s life, over two follow-up periods. The main hypotheses are (a) over a period of time, the sense of control declines by an amount that increases with age; (b) the change in sense of control reflects an underlying change in biosocial function, which accelerates with age; (c) higher social status slows the decline in the sense of control, possibly by preserving biosocial function; and (d) changes in biosocial function and in the sense of control have deviation-amplifying reciprocal effects that accelerate age-dependent changes in the sense of control. This was a three-wave panel survey with fixed 3-year intervals and repeated assessments of the same variables. Questionnaire topics focused on: physical health (subjective health; activities of daily living; height and weight; health conditions; expected personal longevity); health behavior (exercise, smoking, diet, alcohol use); use of medical services (medical insurance coverage, prescription drug use); work status (current employment status; title of current job or occupation and job description; types of work, tasks, or activities; description of work or daily activity and interactions; supervisory status; management position and level; work history); sense of controlextent of agreement or disagreement with planning and responsibility versus luck and bad breaks; sense of victimhood versus control; social support and participation; personal and household demographics; marital and family relations; socioeconomic status; history of adversity. * Dates of Study: 1994-2001 * Sample Size: 2,593 (Waves 1-2); 1.144 (Wave 3) * Study Features: Longitudinal Data Archives: http://www.sscnet.ucla.edu/issr/da/da_catalog/da_catalog_titleRecord.php?studynumber=I3334V1

• Resource
• SciCrunch
• 15 years ago - by Anonymous