We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Standalone software tool to detect cells, to obtain calcium spikes, and to determine underlying network structure of neuronal cell cultures. CALIMA 2.0 is updated version of software tool that detects and analyzes fluorescent signals and correlates cellular activity to identify possible network formation in Brain-on-chip cultures. Used to process calcium fluorescence imaging data.
This resource includes datasets and code related to predicting drug-target interactions, primarily based on a dual-channel heterogeneous graph neural network. We have developed a dual-channel heterogeneous graph neural network that combines sequence and two-dimensional graph data to extract features of drugs and proteins. These features are integrated using a multi-head bilinear attention mechanism. Ultimately, we employ XGBoost for prediction, which is applied in the screening of anti-aging drugs.
Web application for prediction of interactions between two RNA molecules. Used to predict mRNA target sites for given non-coding RNAs (ncRNAs) like eukaryotic microRNAs (miRNAs) or bacterial small RNAs (sRNAs), but it can also be used to predict other types of RNA-RNA interactions. IntaRNAv2 enables enhanced parameterization as well as fully customizable control over prediction modes and output formats.
Web application for RNA-protein interactions prediction.
Software package for visualization of functional enrichment results as network graphs.
Core provides guidance in planning and helps with executing gene expression modulation experiments. Currently uses technology based on shRNA for gene knock-down and cDNA libraries for overexpression studies. Core is equipped with genome-wide retroviral shRNA libraries for both human and mouse genomes, Mammalian Gene Collection (MGC) cDNA library, as well as smaller focused sets targeting selected gene families.
Mouse Behavior Core provides equipment and software for measuring mouse behavior. The MBC can support mouse phenotyping/drug discovery test batteries as well as more focused behavioral projects.
PanoScore is a commercial-grade pathology image analysis platform for quantitative tissue segmentation, AI-powered cell phenotyping, and spatial biology research. It supports whole-slide imaging (WSI), multiplex staining analysis (H&E/IHC/IF), and tissue microarray (TMA) processing, enabling reproducible quantification of tumor microenvironments, cell proximity metrics, and biomarker expression.
Weill Cornell Medicine, originally Cornell University Medical College, is the medical school of Cornell University, located on the Upper East Side of Manhattan in New York City.
Facility serves as central facility for human organoid technology to accelerate organoid-based scientific discovery. Provides human pluripotent stem cell (hPSC) derived as well as tissue derived cells and organoids.
Software Python package for construction of Slepian wavelets in the spherical and manifold (via meshes) settings. Slepian scale-discretised wavelets in Python.
Standalone software and web-based platform for predicting top lncRNA–disease associations using advanced biological feature processing and machine learning. Given input lncRNA or disease, along with associated sequences or target data, PrediLnc uses our custom model GARNet (Graph convolution Attention RNA Network) to return the most relevant predictions.Used for hypothesis generation in biomedical research. LncRNA diseases association predictor.
Arcadia organisms selection portal. Uses data to suggest model organisms based on relevance to human gene of interest or suggest monogenic diseases to model based on organism of interest.
Institutional laboratory of Nuclear Magnetic Resonance (NMR) of the Institute of Chemistry of UNICAMP.The Institutional Nuclear Magnetic Resonance Laboratory has 6 NMR spectrometers, two for solids and four for solution probes, with the possibility of analyzing different nuclei.
Software R package for Affymetrix Human Genome U133 Plus 2.0 Array annotation data.
Cytokine Multiplex Assay Kits allow researchers to simultaneously detect the levels of multiple cytokines in a single sample. This is particularly useful for identifying the wide array of changes that can be associated with different pathological conditions.
This instrument is precision liquid handling instrument that enables non-contact, nanoliter-to-microliter scale dispensing of small molecules, biologics, or other reagents directly into assay plates for high-throughput drug screening and dose-response studies.
Arrayer produces high quality microarrays of DNA, proteins, cell lysates and variety of other samples using its proprietary soft touch deposition technology.