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Core facility that provides the following services: Open repositories service, Sample processing service, Medical/pathology informatics support service, BWH tissue repository service. <BR/> <BR/>The Specimen Bank provides materials to investigators with IRB-approved protocols. Staff are available to assist with selection of samples appropriate for downstream applications, development of processing protocols or preparation of derivatives from clinical materials. IT Staff are also available to assist researchers with creation of queries for prospective sample collection or queries to select samples from specific cohorts. Their goal is to drive quality research in an efficient and cost-effective manner. Each year they provide tens of thousands of samples to area researchers. Getting started: Partners investigators and study staff may request a Crimson user account to help manage studies and collected materials.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented in August 16,2024. Portal, Core facility
Core facility that provides state-of-the-art imaging microscopy technology for fixed and live cells, tissues and multi-photon animal imaging along with scientific and technical expertise to assist in experimental design and optimal image collection. Imaging techniques available include Standard fluorescence, Live-cell long term imaging, Confocal, Deconvolution, Fluorescence spectral detection, TIRF, FRET, Calcium imaging, Multi-photon, and Fluorescence lifetime imaging. Available equipment includes: Yokogawa spinning disk confocal microscope (Andor), Leica SP5 laser scanning confocal with a white light laser, Zeiss 710 confocal/multi-photon, Nikon inverted widefield fluorescence microscope. Other services include training on all equipment, consultation about various imaging techniques and assistance with image analysis. In addition, staff are available to assist with troubleshooting regarding microscopes in individual research labs. All services are available on a fee basis, and equipment is available for either assisted use or unassisted use after training by core staff. NEW: The core has established a collaboration with Rockland Immunochemicals to provide free, trial-size samples of primary and secondary antibodies that may be useful in your experiments.
http://www.niehs.nih.gov/research/supported/srp/funding/index.cfm
Core facility that provides immunostaining (frozen and paraffin embedded tissues) and image processing services in confocal microscopy, light microscopy and immunostaining for cells and tissues including confocal microscopy, brightfield and fluorescence microscopy, and immunoperoxidase and immunofluorescence staining. BIDMC Immunostaining and Microscopy Core offers consultation and service for tissue immunostaining with paraffin or frozen sections, and for training to use confocal and widefield microscopes.
University of Wisconsin Biotechnology Center Mass Spectrometry Core Facility has several mass spectrometers for the analysis of biomolecules, including proteins, peptides, oligonucleotides, oligosaccharides and other small organic and inorganic molecules.
Core facility that provides the following services: Web and graphic services, Web design and content management service, Photography service. Peter Mallen is a designer and illustrator who manages a full-service web and graphics studio in a moderately sized scientific research facility, Schepens Eye Research Institute. He provides a full range of graphic design, scientific illustration, web design and development, content management, and general design and production services. His products are utilized by: faculty and scientific staff (books, scientific publications, slide shows, grant applications); professional staff (Administration, Development & Public Affairs; brochures, books, pamphlets); the general public (Institute websites) as well as clients of our 250-seat state-of-the-art conference center, Starr Center for Scientific Communications.
The Center for Public Health Research (CSISP) provides next generation sequencing services via the GS FLX+ System. The Genome Sequencer FLX+ System, with long-read GS FLX Titanium chemistry, is the flagship 454 Sequencing platform. Offering more than 1 million high-quality reads per run and read lengths up to 700 bases, the system is ideally suited for de novo sequencing of whole genomes and transcriptomes of any size, metagenomic characterization of complex samples, resequencing studies and more. The GS FLX+ System is at the heart of breakthrough scientific discoveries and hundreds of peer-reviewed publications to date. Applications The Genome Sequencer FLX+ System provides the power to address a broad range of applications in diverse fields of biology. The tremendous versatility of the system is based on the unique combination of read length, throughput, and read accuracy. The technology platform has enabled groundbreaking research in various fields. Next we mention some of the most usual applications: _���� Eukaryote and prokaryote whole genome sequencing _���� Metagenomics & Microbial Diversity _���� Transcriptome sequencing _���� HIV sequencing
Comprehensive Integrated Life Science Informatics solutions provider with service offerings that span Sample and Data Management (LIMS, Biologics Data Management), Genomics Data Analysis Services such as Gene Expression, Genotyping, and Next Gen Sequencing, Bioinformatics and Genomics Databases (BioExpress, ToxExpress) and Bio-IT consulting services.
The Experimental Therapeutics Program (ETP) is a program established within the unique MNI environment to pursue a mission of bridging basic research in neurobiology and immunology with human studies of neurological and immune-mediated diseases. The ETP accomplishes this mission through the establishment of core laboratory platforms that integrate fundamental research activities with rigorous studies on human biological samples derived from well-characterized patient populations. The goal of the program is to expedite the development and formal evaluation of emerging therapies aimed at halting and ultimately reversing disability caused by neurological disease.
Core facility offers instrumentation for routine flow cytometry and cell sorting. Offers expertise and services including assisting in setting up flow cytometry experiments, acquiring, analyzing and interpreting data, data presentation and data storage, providing training with analyzers and software usage.
Software tool as data transformation algorithm that restructures data in such a way that the transformed message is more compressible. Used for large scale compression of genomic sequence databases.
Self use flow cytometry facility. All new users must be trained by the facility manager over two orientation sessions and be approved to use the equipment in the facility.
Core facility that positions digital imaging resources right where the research is being done: in Harvard Medical School''s quad-based basic science departments. The convenience of these locations makes it easy for researchers to access digital imaging expertise when faced with research imaging questions. This accessibility and convenience is supplemented by substantial web-based assistance, making Research Imaging Solutions a 24/7 resource. Seminars, Workshops and printed training materials guide faculty, students, post-docs and lab personnel on supported imaging hardware and software products. Supported hardware and software packages includes: Adobe products including Acrobat, Photoshop, and Illustrator; ACD Canvas; Microsoft Office applications including Word, PowerPoint and Excel; film recorders, slide and flatbed scanners, and color output devices such as color laser printers, poster printers and photo quality printers.
Core facility that provides the following services: SNP genotyping, qPCR for CNV detection / confirmation, Genetic analysis services, DNA extraction, quantification, sample preparation, tracking, and storage. This resource provides custom genotyping (SNP, other), qPCR for CNV detection/confirmation, DNA extraction, quantification, sample preparation, tracking, and storage, and related services to further the PNGU mission of identifying and characterizing the genetic basis of psychiatric, behavioral, and neurodevelopmental disorders and to translate these discoveries to improvements in clinical care and public health.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 4th, 2023. Handles both low-level (instrument-specific, or upstream) informatics as well as higher-level (hypothesis testing and generation oriented, or downstream informatics). CHIBI also has the scientific responsibility for the high-end computing needed to process the genomic data.
Core facility that provides the following services: Rodent and Porcine Islet Isolation Services, Training Services. The main objective of the Islet Isolation Core is to provide Islets of Langerhans to investigators in the Boston area and beyond. By receiving islets from the Core one is assured of consistent high quality and purity of islets for experiments. The Core can isolate rodent and neonatal porcine islets. This leaves the investigator to concentrate on experiments rather than the complexity of islet isolation. The Core can buy the animals or the investigator can provide their own, such as special transgenic mice. Over the last five years the Core has isolated more than 10 million islets. They also provide training and advice. The Core can provide training not only for the isolation procedure but islet viability, islet size measurement, GSIS (Glucose Stimulated Insulin Secretion), STZ-induced diabetes, transplantation under the kidney capsule, and islet graft retrieval.
Core provides centralized, standardized, accurate, consistent, and timely longitudinal, multimodality anatomic, volumetric and functional tumor metrics including CT, MR, PET/CT and other nuclear medicine imaging studies to evaluate therapeutic response for patients enrolled in DF/HCC oncologic clinical trials. TIMC supports more than 30 tumor response assessment criteria including but not limited to RECIST 1.1, iRECIST, Lugano, LYRIC, IWCLL and RANO. Results of tumor metric analyses are offered on password-protected secure web-based report.
Core provides support to life science researchers with data analysis and experimental design from sequence analysis, microarrays, proteomics and beyond.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. Portal, Core facility