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THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. The laboratory at Purdue is equipped with advanced instrumentation for small molecule crystallography. The main diffractometer is equipped with a micro-focus x-ray source to allow very small crystals (less than 0.1 mm) to be studied. Low temperature data collection is available to a temperature of 95K. The crystallographer has been at Purdue for over 26 years and is widely respected.
Provides instruments and expertise needed to visualize molecules in preparations ranging from single cells to entire animals. All facility users receive individualized instrument training as well as project specific advice for optimal data acquisition. Consultation on sample preparation, image rendering, and data analysis are also available as our knowledge base permits.
Purdue Translational Pharmacology (PTP) facility provides in vivo pharmacological evaluation using porcine models. The facility is situated in the Purdue University School of Veterinary Medicine complex, which provides constant care and monitoring of the animals. The PTP uses unique penning systems to automate blood sampling and maintain a humane and stress free environment for test subjects. The PTP synergizes with the Metabolite Profiling Facility in the Bindley Bioscience Center, which facilitates the pharmacological analysis of blood samples collected.
The Bindley Bioscience Flow Cytometry and Cell Separation Facility provides advanced cell and particle analysis and sorting using flow cytometry based technology. The facility also provides training in flow cytometry analysis and sorting techniques. The facility also provides expert consultation for assay and protocol development for flow cytometry analysis and cell separation.
The Metabolite Profiling Facility (MPF) provides state-of-the-art technologies that enable both qualitative (defining all components of a metabolome) and quantitative (determining differential concentrations of metabolites) metabolomics in complex biological systems. This facility employs highly sensitive mass spectrometry coupled with liquid chromatography and multi-dimensional gas chromatography for precise sample analysis. Metabolite profiling is an integral component of systems biology, an exciting field that combines genomics, transcriptomics and proteomics to define cellular functionality. Our elite scientists will empower researchers with new technologies, methods development, expert training and consultation.
Provides LCMS/MS analysis of proteins in clinical, environmental and other biological samples. As a shared facility of the Bindley Bioscience Center (BBC) in Discovery Park of Purdue University, the facility enables both targeted and global analysis of proteins, their post-translational modifications and analysis of protein complexes and protein-protein interactions. Coupled with different chromatographic separation techniques, modern mass spectrometric instrumentation, and advanced scientific and bioinformatics expertise, the facility provides unique opportunities for researchers at Purdue and beyond to perform quantitative analysis of proteins in complex biological samples using both global, as well as, targeted proteomic approaches.
Our insectary produces five rodent malaria strains weekly and will ship live sporozoite infected Anopheles stephensi to investigators for research use (Plasmodium berghei GFP, luciferase or red-star and P. yoelii-GFP) Anti-infective testing including in vitro EC50, in vivo mice infection are available against for major parasitic diseases: Malaria, Leishmaniasis, Chagas and African Trypanosomiasis.
The purpose of the Biophysical Analysis Lab (BAL) at the Bindley Biosciences Center is to provide complete biophysical analysis of macromolecules. In the lab, there are two analytical ultracentrifuges: Beckman-Coulter XLI and XLA, a Biacore 3000, an ITC, and a SEC-MALS platform. With these instruments we can determine kinetic parameters, stoichiometry of binding, size distribution, shape, oligomerization state and other biophysical measurements. Complementing these traditional biophysical methods, the BAL also provides mass spectrometric analyses at both the protein and peptide levels. The lab strives to establish long-term collaborations and deliver professional quality data that can be used for publications and grant proposals.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. Protein X-ray Crystallography Facility became operational in October 2010 following the acquisition of a Rigaku HighFlux HomeLab system with funding awarded by the VPR''s Major Equipment Competition in November 2009.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 15,2024. Nuclear Magnetic Resonance Facility (NMR) was established in 2004. The Facility recognizes the important role that NMR plays in molecular structure determination, drug design, protein and nucleic acid characterization, and conformational analysis. The instrumentation serves the high-resolution research needs for investigators from the Departments of Molecular and Cell Biology, Chemistry, and Pharmacy at the University of Connecticut.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 16, 20224. Nanofabrication Facility houses three instruments for patterning of flat surfaces and selective etching of materials. Researchers fabricate devices and structures to demonstrate novel device concepts and to characterize new materials. To carry out these functions this new facility consists of three instruments: a Tescan Electron-Beam Lithography Tool, an OAI high resolution Mask Aligner and Advanced Vacuum/Plasma Therm Reactive Ion Etcher.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 22,2024. Microcalorimetry Facility was established in 2011 as the result of the acquisition of nano-ITC (Isothermal Titration) and nano-DSC (Differential Scanning) Calorimeters from TA Instruments, which was made possible with funding awarded through the VPR''s Major Equipment Competition in October 2010.
The University of Connecticut High-Throughput Screening Facility (HTS Facility) was established in 2011 with funding awarded through the University''s Major Equipment Competition. Over the last 20 years, high-throughput screening has become an integral tool utilized by both pharmaceutical industry and academic institutions to identify new lead compounds for drug development. The HTS Facility is comprised of integrated instrumentation dedicated to aiding researchers in the small molecule screening and drug discovery process.
An Portal, Core facility
Public research university in the Australian state of Western Australia. The university's main campus is in Perth, the state capital, with a secondary campus in Albany and various other facilities elsewhere.
Facility provides advanced analytical and cell‑sorting services to support research in immunology, cancer biology, stem cell biology, oceanography, microbiology, and translational medicine. Combines high‑parameter cytometry, precision cell sorting, and expert scientific support to enable deep single‑cell characterization across a wide range of experimental systems.
The Analytical Ultracentrifugation Facility located at the University of Connecticut engages in collaborative research as well as training scientists, technicians, and students. The Facility has three Beckman XL-I ultracentrifuges along with associated instruments, hardware and computers. In addition, University scientists are on hand to provide user support and advice.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. Portal, Core facility
Genetik Ink creates art from your own DNA. From a simple cheek swab, we collect your DNA, process it, and create an art piece on canvas or aluminum. Once you order, a DNA collection kit will be sent in the mail to you. Once you have collected your DNA, send it back to our lab with the mailer sleeve we provided in the kit. We take care of the rest. Typically, you can expect to have your art piece within 1-2 weeks. Since we are in beta phase of our business, development could take longer. If you are not happy with your final product, we have a 100% money back guarantee
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 19,2024. Core facility