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A consortium of researchers conducting a cohort study that investigates the underlying disease mechanisms of pro non-inflammatory glomerular diseases. The aim is to elucidate pathogenesis and identify therapeutic targets for clinical trials. The study participants will be classified according to the kidney biopsy results into one of three subcohorts, including Minimal change disease/Focal segmental glomerulosclerosis; Membranous nephropathy; and other conditions.

• Resource
• dkNET
• 11 years ago - submitted by Ko-Wei Lin

A consortium which includes five of the leading porphyria centers in the United States that provide expertise and experience in the diagnosis and treatment of patients with porphyria. The staff in each Center includes porphyria physicians, researchers, research coordinators, and technical/laboratory staff. Together with the American Porphyria Foundation, the Porphyrias Consortium enables a large scale collaborative effort to develop strategies and methods for diagnosis, treatment, and prevention of illness and disability resulting from these rare disorders.

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• dkNET
• 11 years ago - submitted by Ko-Wei Lin

A research consortium with the long term goal of developing and testing measurement tools to describe symptoms of lower urinary tract dysfunction (LUTD) in women and men. The group plans to study targeted populations of patients with LUTD in order to expand our understanding of the causes of symptoms and common ways that symptoms change over time. The researchers will also collect biosamples from patients for current and future study of LUTD.

• Resource
• dkNET
• 11 years ago - submitted by Ko-Wei Lin

The goal of this follow-up study of mothers who participated in the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study is to determine the levels of blood sugar during pregnancy that are linked to increased body fat in the child, as well as to determine the chances of a mother developing diabetes 8-12 years after the pregnancy. The original study examined 23,316 mother-child pairs, and researchers determined that the hyperglycemia of a mother was linked to newborn birth weight and body fat. HAPO-FUS will enroll 7,000 or the original HAPO mother-child pairs for one follow-up visit to assess body composition, blucose metabolism, medical history, and other metabolic parameters.

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• dkNET
• 11 years ago - submitted by Ko-Wei Lin

A consortium whose overall goal is to identify effective behavioral and lifestyle interventions that will improve weight, glycemic control and other pregnancy-related outcomes in obese and overweight pregnant women, and determine whether these interventions reduce obesity and metabolic abnormalities in their children. The study/consortium is comprised of seven clinical centers, with each clinical center conducting its own trial. Additional information on the consortium and individual trials is located in the Consortium Summaries tab.

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• dkNET
• 11 years ago - submitted by Ko-Wei Lin

Collaborative research network specializing in urological chronic pelvic pain disorders. Project involves conducting research primarily on interstitial cystitis/painful bladder syndrome and chronic prostatitis/chronic pelvic pain syndrome and involves researchers from multiple disciplines. MAPP Network includes researchers with clinical, epidemiological, and basic research expertise.

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• dkNET
• 11 years ago - submitted by Ko-Wei Lin

A study of how children newly diagnosed with ulcerative colitis (UC) respond to mesalamine and prednisone (corticosteroid), the standard initial therapies used to treat this disorder. Over a period of 5 years PROTECT will prospectively study the course of 430 children newly diagnosed with UC who are treated with standardized care. Biospecimens (blood, stool, colonic biopsy tissue) will be obtained and used to better understand the effects of genetics, mechanisms of inflammation, Vitamin D, and the bacteria contained in the stool (microbiome) on clinical outcomes.

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• dkNET
• 11 years ago - submitted by Ko-Wei Lin

A prospective, observational follow-up study of at least 8000 participants who were treated and followed in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial. Treatment in ACCORD ended in 2009 and ACCORDION is designed to further elucidate the long-term effects of the ACCORD treatment strategies and provide additional data on the relationships among various cardiovascular and diabetic risk factors.

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• dkNET
• 11 years ago - submitted by Ko-Wei Lin

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 29,2023. Registry listing NIDDK resources, such as reagents, data, and protocols. They are derived from publicly available information provided by NIDDK-funded investigators, projects, and publications.

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• dkNET
• 11 years ago - submitted by Ko-Wei Lin

Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding His108 of human Cox2 protein.

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• SciCrunch
• 11 years ago - by Anonymous

• SciCrunch
• 11 years ago - by Anonymous

The cytokine registry is a master list of cytokines, chemokines and receptors generated for the purpose of collecting, integrating and mapping between entity names and synonyms from several resources. These resources include MeSH, the Protein Ontology, EntrezGene, HGNC, MGI, UniProt and others. Contributors: Nophar Geifman1, Ksenya Kveler2, Amit Ziv-Kenet2, Kei Cheung 3, Steven Kleinstein3, Alan Ruttenberg4, Alex Diehl5, Shai Shen-Orr2, Barry Smith6 and Sanchita Bhattacharya1 Institute of Computational Health Sciences, University of California, San Francisco, CA Department of Immunology, Rappaport Institute of Medical Research, Technion, Haifa 32000, Israel. Interdepartmental Program in Computational Biology and Bioinformatics and Department of Pathology, Yale University School of Medicine, New Haven, CT 06510 School of Dental Medicine, State University of New York at Buffalo, Buffalo, New York, United States of America. Department of Neurology, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY 14203, USA 6. Department of Philosophy, University at Buffalo, NY, USA.

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• SciCrunch
• 11 years ago - submitted by Anita Bandrowski

A registry of cytokines, chemokines, and receptors generated for the purpose of collecting, integrating, and mapping between entity names and synonyms from several resources. These resources include MeSH, the Protein Ontology, EntrezGene, HGNC, MGI, UniProt and others.

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• SciCrunch
• 11 years ago - submitted by Anita Bandrowski

A kit which enables isolation and enrichment for intact lysosomes from crude cell and tissue extracts. The kit provides sufficient reagents for preparing 25 extracts and uses OptiPrep Cell Separation Media for the density-based separation of lysosomes from contaminating cell structures.

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• SciCrunch
• 11 years ago - submitted by Michael Marshall

A sterile-filtered solution of DAPI, 2HCl in water that serves as a cell permeable nuclear stain.

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• SciCrunch
• 11 years ago - submitted by Daniel DuBreuil

A conjugated form of isolectin B4 for fluorescence identification of non-peptidergic nociceptors in mouse dorsal root ganglia and spinal cord.

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• SciCrunch
• 11 years ago - submitted by Daniel DuBreuil

An application which provides an environment to explore and organize scholarly data. Rexplore leverages solutions in large-scale data mining, semantic technologies and visual analytics, which allows users to detect and follow research trends, identify and map relationships between authors, perform expert searches, and analyze research performance.

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• SciCrunch
• 11 years ago - by Anonymous

Software tool for automatically scheduling events for rapid-presentation event-related (RPER) fMRI experiments (the schedule is the order and timing of events). Events in RPER are presented closely enough in time that their hemodynamic responses will overlap. This requires that the onset times of the events be jittered in order to remove the overlap from the estimate of the hemodynamic response. RPER is highly resistant to habituation, expectation, and set because the subject does not know when the next stimulus will appear or which stimulus type it will be.

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• SciCrunch
• 11 years ago - submitted by Maryann Martone

A cross-platform integrated development environment (IDE) for Free Pascal. It contains a class library (LCL) that supports rapid application development for native code on numerous platforms, processor architectures and operating systems.

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• SciCrunch
• 11 years ago - submitted by Johannes W. Dietrich

Specific, sensitive, precise and accurate CLIA for 3,5-T2 detection in human serum.

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• SciCrunch
• 11 years ago - submitted by Johannes W. Dietrich