Curator Dashboard

Software that aims to interrogate and perform detailed analysis on small RNAs derived from annotated non-coding regions.

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• SciCrunch
• 13 years ago - by Anonymous

Database of ascidian embryonic development at the level of the genome (cis-regulatory sequences, gene expression, protein annotation), of the cell (morphology, fate, induction, lineage) or of the whole embryo (anatomy, morphogenesis). Currently, four organism models are described in Aniseed: Ciona intestinalis, Ciona savignyi, Halocynthia roretzi and Phallusia mammillata.<BR/> This version supports four sets of Ciona intestinalis transcript models: JGI v1.0, KyotoGrail 2005, KH and ENSEMBL, all functionally annotated, and grouped into Aniseedv3.0 gene models. Users can explore their expression profiles during normal or manipulated development, access validated cis-regulatory regions, get the molecular tools used to assay gene function, or all articles related to the function, or regulation of a given gene. Known transcriptional regulators and targets are listed for each gene, as are the gene regulatory networks acting in individual anatomical territories. <BR/> ANISEED is a community tool, and the direct involvement of external contributors is important to optimize the quality of the submitted data. Virtual embryo: The 3D Virtual embryo is available to download in the download section of the website.

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• SciCrunch
• 17 years ago - by Anonymous

The goal of the Genetic Testing Reference Materials Coordination Program (GeT-RM) is to coordinate a self-sustaining community process to improve the availability of appropriate and characterized reference materials for: Quality control (QC), Proficiency testing (PT), Test development &amp; validation, Research. The purpose of this program is: - To help the genetic testing community obtain appropriate and characterized reference materials - To facilitate and coordinate information exchange between users and providers of QC and reference materials - To coordinate efforts for contribution, development, characterization and distribution of reference materials for genetic testing Get-RM provides information about cell lines, DNA, and other kinds of materials that could be used as reference materials for molecular genetic testing. Some of these materials have been characterized by the GeT-RM program and can be divided into three categories: - Genetic Inherited Disease & Pharmacogenetics This section includes information about cell lines, DNA, and other samples that can be used as reference materials for various inherited diseases (including cystic fibrosis, fragile X, Huntington disease, and Ashkenazi Jewish-related diseases), pharmacogenetic loci, and biochemical genetics. The GeT-RM program has confirmed the genotype of many of the genomic DNA samples through testing in multiple clinical genetic laboratories. - Molecular Oncology This section includes information about commercially available cell lines, DNA, and other kinds of materials that could be used as reference materials for various types of cancers, including leukemia/lymphoma and solid tumors. - Infectious Disease This section includes information about commercially available cell lines, DNA, and other kinds of materials that could be used as reference materials for various infectious disease pathogens including viruses, bacteria, and protozoa.

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• SciCrunch
• 17 years ago - by Anonymous

This resource gives information about the U.S. Human Genome Project, which was was a 13-year effort to to discover all the estimated 20,000-25,000 human genes and make them accessible for further biological study. The primary project goals were to: - identify all the approximately 20,000-25,000 genes in human DNA, - determine the sequences of the 3 billion chemical base pairs that make up human DNA, - store this information in databases, - improve tools for data analysis, - transfer related technologies to the private sector, and - address the ethical, legal, and social issues (ELSI) that may arise from the project. To help achieve these goals, researchers also studied the genetic makeup of several nonhuman organisms. These include the common human gut bacterium Escherichia coli, the fruit fly, and the laboratory mouse. These parallel studies helped to develop technology and interpret human gene function. Sponsors: The DOE Human Genome Program and the NIH National Human Genome Research Institute (NHGRI) together sponsored the U.S. Human Genome Project.

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• SciCrunch
• 17 years ago - by Anonymous

A computational tool for analyzing the microRNA (miRNA) transcriptome in plants.

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• SciCrunch
• 13 years ago - by Anonymous

A software tool which can be used to identify both known and novel microRNAs from small RNA libraries deeply sequenced by Solexa/454/Solid technology.

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• SciCrunch
• 13 years ago - by Anonymous

A software tool to find microRNAs with high accuracy and no learning at genome scale and from deep sequencing data.

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• SciCrunch
• 13 years ago - by Anonymous

Data analysis service that predicts whether a given mRNA is targeted by a set of miRNAs. ComiR uses miRNA expression to improve and combine multiple miRNA targets for each of the four prediction algorithms: miRanda, PITA, TargetScan and mirSVR. The composite scores of the four algorithms are then combined using a support vector machine trained on Drosophila Ago1 IP data.

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• SciCrunch
• 13 years ago - by Anonymous

Atlas of the brain and the disorders affecting it, aimed at general practitioners and specialists in training. It consists of three main parts: a description of the different parts of the normal brain and their functions, a description of the process of neurological control, and a description of 14 different brain disorders in psychiatry and neurology - as well as their cause, symptoms, and treatment.

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• SciCrunch
• 17 years ago - by Anonymous

A resource for animal miRNA-target interactions consisting of the Validated Targets component, a large, high-quality database of experimentally validated miRNA targets resulting from meticulous literature curation, and the Predicted Targets component, an integration of predicted miRNA targets produced by 11 established miRNA target prediction programs. April 27, 2013, the Validated Targets component of miRecords hosts 2705 records of interactions between 644 miRNAs and 1901 target genes in 9 animal species. Among these records, 2028 were curated from low throughput experiments. The Predicted Targets component of mIRecords integrates the predicted targets of the following miRNA target prediction tools: DIANA-microT, MicroInspector, miRanda, MirTarget2, miTarget, NBmiRTar, PicTar, PITA, RNA22, RNAhybrid, and TargetScan/TargertScanS. We would be glad to include your experimentally validated miRNA target data (published or unpublished) into miRecords., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

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• SciCrunch
• 13 years ago - by Anonymous

Software for a genome wide mapping data interpretation platform for NGS (ChIPSeq).

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• SciCrunch
• 13 years ago - by Anonymous

Software tool for base and quality calling of trace files from DNA sequencing instruments.

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• SciCrunch
• 13 years ago - by Anonymous

An open source package for primary data analysis on next-gen sequence data from images to basecalls. Currently Swift is targeted toward Solexa/Illumina sequencing, but is designed to be platform agnostic.

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• SciCrunch
• 13 years ago - by Anonymous

Software that provides probabilistic base calling, quality checks and diagnostic plots for Solexa sequencing data.

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• SciCrunch
• 13 years ago - by Anonymous

Software that identifies protein binding sites from ChIP-seq and nucleosome positioning experiments.

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• SciCrunch
• 13 years ago - by Anonymous

The Division of Biology and Biomedical Sciences at Washington University in St. Louis offers exceptional doctoral training at one of the nations preeminent biomedical research centers. The Division consists of 12 doctoral training programs, 10 of which are ranked among the nations top 10.* :A collaborative, interdisciplinary approach to research and education is a hallmark of Washington University and the Division. As a university-wide consortium, the Division transcends departmental lines and removes traditional boundaries of scientific fields. Faculty and graduate students regularly cross disciplines, devising novel questions and approaches that might otherwise go unexplored. The Division currently consists of 685 graduate students and 410 faculty members from 32 university-wide departments..

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• SciCrunch
• 17 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE,documented on August 16, 2019. Fugu genome is among the smallest vertebrate genomes and has proved to be a valuable reference genome for identifying genes and other functional elements such as regulatory elements in the human and other vertebrate genomes, and for understanding the structure and evolution of vertebrate genomes. This site presents version 4 of the Fugu genome, released in October 2004 by the International Fugu Genome Consortium. Fugu rubripes has a very compact genome, with less than 15 consisting of dispersed repetitive sequence, which makes it ideal for gene discovery. A draft sequence of the fugu genome was determined by the International Fugu Genome Consortium in 2002 using the ''whole-genome shotgun'' sequencing strategy. Fugu is the second vertebrate genome to be sequenced, the first being the human genome. This webpage presents the annotation made on the fourth assembly by the IMCB team using the Ensembl annotation pipeline. We are continuing with the gap filling work and linking of the scaffolds to obtain super-contigs.

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• SciCrunch
• 17 years ago - by Anonymous

The information in this manual is presented to assist health care professionals caring for cancer patients undergoing treatment with cytotoxics, hormones or biological response modifiers. It is designed primarily for pharmacists and nurses in general practice, and may also be of interest to the family physician who is treating a patient in consultation with an oncologist. Efforts have been made to include information specific to the use of these drugs in the child with cancer. Because of the nature of individual drug monographs, this manual does not deal with therapeutics. For treatment decisions, the reader is referred to the protocol by which the patient is being treated, to the British Columbia Cancer Agency''s Cancer Management Manual and to the most current literature. The Cancer Drug Manual also provides a drug index for physicians and patients. The BC Cancer Agency, an agency of the Provincial Health Services Authority, provides a province-wide, population-based cancer control program for the residents of British Columbia and the Yukon. The BC Cancer Agencys mandate covers the spectrum of cancer care, from prevention and screening, to diagnosis, treatment, and through to rehabilitation. The BC Cancer Agencys mandate is driven by a three-fold mission: -To reduce the incidence of cancer -To reduce the mortality rate of people with cancer -To improve the quality of life of people living with cancer

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• SciCrunch
• 17 years ago - by Anonymous

A microsatellite database of commercially important fishes and shellfishes of the Indian subcontinent.

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• SciCrunch
• 13 years ago - by Anonymous

Software package that is an implementation of the BayesPeak algorithm for peak-calling in ChIP-seq data.

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• SciCrunch
• 13 years ago - by Anonymous