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University of California San Diego - University of California Los Angeles Diabetes Research Center
Research center across five institutions for clinical research in diabetes. Collaborators include UC San Diego's School of Medicine, Salk Institute, Cedars-Sinai Medical Center, UC Los Angeles' School of Medicine, and LA Biomedical Research Center.
- Resource
- SciCrunch
- 10 years ago - submitted by Kristen Jensen
University of California San Diego - University of California Los Angeles Diabetes Research Center Human Genetics Core Facility
Core provides services such as assistance in the development and successful completion of well-designed genetic studies, establishment and storage of EBV-transformed lymphoblastoid cell lines (LCLs), as well as PAXgene tubes, and specialized (e.g., the exome chip) single nucleotide polymorphism (SNP) testing, candidate gene sequencing, whole exome sequencing (WES), whole genome sequencing (WGS), and large-scale gene methylation analysis.
- Resource
- SciCrunch
- 10 years ago - submitted by Kristen Jensen
University of California San Diego - University of California Los Angeles Diabetes Research Center Targeted Pathway Analysis Core Facility
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 8, 2024. Core with main goal to steer investigators through introductory discovery lipidomics and proteomics experiments toward statistically powered, targeted experiments aimed at measuring biological pathways relevant to diabetes and metabolism.
- Resource
- SciCrunch
- 10 years ago - submitted by Kristen Jensen
University of California San Diego - University of California Los Angeles Diabetes Research Center Genomics and Epigenetics Core Facility
Core which provides Diabetes Research Center investigators access to high-throughput sequencing, data acquisition and analysis. Its main services include Sample QC and Processing, Illumina Platform Library Preparation and Sequencing, and Expression microarrays (RNA, microRNA).
- Resource
- SciCrunch
- 10 years ago - submitted by Kristen Jensen
University of California San Diego - University of California Los Angeles Diabetes Research Center Transgenic and Knockout Mouse Core Facility
Core that provides and produces transgenic mice. Services and methodologies include pronuclear microinjection and blastocyst microinjection for creation of new mouse cell lines as well as archival services like embryo and sperm freezing.
- Resource
- SciCrunch
- 10 years ago - submitted by Kristen Jensen
University of California San Diego - University of California Los Angeles Diabetes Research Center Metabolic and Molecular Physiology Core Facility
Provides DRC investigators with thorough scientific consultation and timely, accurate, and easily accessible mouse, tissue, and cellular phenotyping. Services include whole animal, tissue and cellular metabolism, insulin action, and inflammatory signaling as well as cardiac, vascular and renal phenotyping associated with diabetes complications research. It also administers drugs and other substances to mice by different routes in a well-controlled setting.
- Resource
- SciCrunch
- 10 years ago - submitted by Kristen Jensen
Joslin Diabetes Center Enrichment Core
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 9,2024. Six component core which facilitates the exchange of research information and discussions among investigators, fellows and students within the Joslin Diabetes Center, as well as between Joslin Staff and outside researchers with similar interests.
- Resource
- SciCrunch
- 10 years ago - submitted by Kristen Jensen
Johns Hopkins University - University of Maryland Diabetes Research Center Health and Populations Science Core
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 9,2024. Contains description of and contact information for multiple health and social science departments.
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- SciCrunch
- 10 years ago - submitted by Kristen Jensen
Joslin Diabetes Center Bioinformatics and Biostatistics Core
Core that offers support for data-driven projects related to basic, clinical and translational research, with a particular emphasis on diabetes. The core aims to ensure that researchers take advantage of the most modern and robust methods available in the field of Bioinformatics and Biostatistics.
- Resource
- SciCrunch
- 10 years ago - submitted by Kristen Jensen
Johns Hopkins University - University of Maryland Diabetes Research Center Gene Editing Core
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 9,2024. Core that provides services in Gene Editing Expertise Using CRISPR/CAS9, Conventional Transgenic Mouse Generation, Conventional Knockout, Knock-In Mouse Generation, and Cryopereservation of Sperm, Oocytes and Embryos.
- Resource
- SciCrunch
- 10 years ago - submitted by Kristen Jensen
Johns Hopkins University - University of Maryland Diabetes Research Center Cell Biology Core
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 9,2024. Core that provides services in tissue analysis and imaging, islet biology, liver biology, and adipocyte biology. It includes the indepedent cores Derivation of IPSC and Bioenergetics as well as the Specialty Animal Surgery Subcore and Bone Biology Subcore.
- Resource
- SciCrunch
- 10 years ago - submitted by Kristen Jensen
Indiana Diabetes Research Center Swine Core
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 14,2024. Core which utilizes a breeding colony of Ossabaw swine with metabolic syndrome and long-term complications, most notably cardiovascular disease. It provides swine maintenance (glucose tolerance tests, body composition, glucose clamp studies, and imaging studies), characterization of cardiovascular disease (intravascular ultrasound, blood flow velocity, microvascular studies), and tissues (both banked and fresh) for analysis ex vivo.
- Resource
- SciCrunch
- 10 years ago - submitted by Kristen Jensen
Johns Hopkins University - University of Maryland Diabetes Research Center Integrated Physiology Core
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 24,2024. Core consisting of several subcores: Ligand Assay and Biomarker Subcore (offers services in Multiplex Assay Detection Systems, Comprehensive Laboratory Animal Monitoring System (CLAMS), and Body Composition), Rodent Physiology and Behavioral Analysis Subcore, and Glucose Metabolism Analysis Subcore (provides services in Dynamic Physiologic Testing).
- Resource
- SciCrunch
- 10 years ago - submitted by Kristen Jensen
Johns Hopkins University - University of Maryland Diabetes Research Center Administrative Core
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 24,2024. Core that typically organizes a meeting with the investigator/user and relevant core directors to discuss the different services and tests that the Diabetes Research Center would recommend to the investigator. It also provides support letters for grant proposals submitted by investigators.
- Resource
- SciCrunch
- 10 years ago - submitted by Kristen Jensen
Johns Hopkins University - University of Maryland Diabetes Research Center
Center whose goal is to understand the causes of both type 1 and 2 diabetes and promotes translational research that is aimed at reducing the burden of these diseases in the U.S. It has a specific focus on childhood diabetes and diabetes that affects minority populations.
- Resource
- SciCrunch
- 10 years ago - submitted by Kristen Jensen
Columbia Diabetes Research Center Advanced Tissue Pathology and Imaging Core Facility
Core that provides spectrum of advanced cellular and tissue pathology and imaging services for diabetes researchers at Columbia University. It also has microscopy equipment and services such as confocal, live 2-photon and scanning and transmission electron microscopy.
- Resource
- SciCrunch
- 10 years ago - submitted by Kristen Jensen
Indiana Diabetes Research Center Translation Core Facility
Core within Indiana Center for Diabetes and Metabolic Diseases that offers services that facilitate conduct of research involving human subjects, including providing low-cost, high quality analyte measurements for variety of hormones, cytokines, lipids and other analytes. Its human studies services include metabolic phenotyping (e.g. GTT, clamp studies, tracer studies), and access to a biobank of human tissues and serum.
- Resource
- SciCrunch
- 10 years ago - submitted by Kristen Jensen
Indiana Diabetes Research Center Microscopy Core Facility
Core that provides consultation and specialized services for intravital microscopy of pancreas and transplanted islets, FRET assays, and fluorescent biosensors for analysis of intracellular signaling cascades to serve the area diabetes investigators.
- Resource
- SciCrunch
- 10 years ago - submitted by Kristen Jensen
Columbia Diabetes Research Center Mouse Metabolic Function and Phenotyping Core Facility
Core that provides services that facilitate the efficient characterization of mouse models of diabetes and its complications: NMR Body Composition Analysis, Whole Body Metabolic Assessment (chamber calorimetry with motion detection), Metabolic Clamps, Gastric Infusion/Feeding and Thermogenic Phenotyping.
- Resource
- SciCrunch
- 10 years ago - submitted by Kristen Jensen
Indiana University School of Medicine Center for Diabetes and Metabolic Diseases Islet and Physiology Core Facility
Services include islet isolation services from mice and rats and access to porcine and human islets. The core is equipped with BioRep Perifusion Apparatus for measurement of insulin secretion and offers services for islet and beta cell calcium imaging. Provides services for islet transplantation and assists investigators who wish to perform immunohistochemistry, immunofluorescence and/or analysis of endocrine or beta cell mass on whole pancreata from mouse and rat models.Offers services for rodent metabolic characterization, including performance of insulin and glucose tolerance testing, analysis of body composition, and metabolic cage analysis using the TSE System cages. Recently added services include zebrafish characterization to screen genes and small molecules for their effects on islet development and function.
- Resource
- SciCrunch
- 10 years ago - submitted by Kristen Jensen
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