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Core facility which provides researchers access to and technological support for advanced cellular microscopy and tools.

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• SciCrunch
• 10 years ago - submitted by Kristen Jensen

Clinical Core of the Michigan Diabetes Research Center (MDRC) provides expertise and services to support basic biomedical research, research focused on the translation of basic science findings into early phase clinical trials, and the testing of treatments related to diabetes in human subjects.

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• SciCrunch
• 10 years ago - submitted by Kristen Jensen

University-affiliated center established to support and enhance research in diabetes and related metabolic diseases. Its long-term goal is the development of new preventive strategies and therapies aimed at improving the lives of Americans with or at risk for diabetes.

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• SciCrunch
• 10 years ago - submitted by Kristen Jensen

Core facility which provides mass spectrometry analyses to Diabetes Research Center investigators that includes quantification as well as structural characterization of diabetes-related biomolecules.

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• SciCrunch
• 10 years ago - submitted by Kristen Jensen

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 7,2024. Core facility with the goal of assisting Diabetes Research Core investigators in obtaining metabolic tissues and conducting functional and metabolic analysis of cells and tissues relevant to the pathogenesis of diabetes.

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• SciCrunch
• 10 years ago - submitted by Kristen Jensen

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 7,2024. Core which provides expertise and services that range from methods of intervention development, basic study design and data analysis, and cutting-edge methodologies in measurement, to subject recruitment and retention strategies with an emphasis on increasing minority participation.

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• SciCrunch
• 10 years ago - submitted by Kristen Jensen

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 7,2024. Core whose goal is to facilitate the use of model organisms in diabetes and metabolism-related research. The Core provides access to resources, technology, equipment and services for the generation and study of genetically modified mice and other model organisms; consultation on experimental design and analysis; technology development; and opportunities for collaboration and training.

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• SciCrunch
• 10 years ago - submitted by Kristen Jensen

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 6,2024. Fee-for-service laboratory that provides consultation and utilizes specialized skills and equipment to assess the metabolic state and related endocrine and behavioral phenotypes of rats and mice. The labs include Rat Metabolic Phenotyping Lab, Optogenetics and Behavioral Phenotyping Lab, Islet Laboratory, and Continuous Glucose Monitoring Lab.

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• SciCrunch
• 10 years ago - submitted by Kristen Jensen

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 7,2024. Core which provides services and hands-on training in the isolation and functional characterization of pancreatic islets from normal and diabetic humans and mice. It also maintains a repository of insulinoma cell lines for distribution. It puts emphasis on facilitating studies of primary islet cells and it has developed many unique tools and techniques for carrying such studies including novel animals models, biophysical methods and a library of adenovirus-based expression constructs for studying beta-cell function.

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• SciCrunch
• 10 years ago - submitted by Kristen Jensen

Core facility that provides the powerful tools of modern mass spectrometry and complex data set analysis to Diabetes Research Center investigators to permit structural identification and quantitation of proteins involved in diabetes and its complications.

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• SciCrunch
• 10 years ago - submitted by Kristen Jensen

Core facility that provides Diabetes Research Center affiliates with vectors necessary to overexpress, knockdown, knockout, or alter expression of RNAs and proteins of interest in cultured cells, isolated tissues, and animals.

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• SciCrunch
• 10 years ago - submitted by Kristen Jensen

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 7,2024. Molecular biology and genetics core which helps independently funded investigators with an interest in diabetes mellitus and other metabolic disorders to clone, sequence and characterize cDNAs and genes of interest. It also provides research tools and expertise to enable investigators to discover how genetic variation in diabetes genes leads to hyperglycemia.

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• SciCrunch
• 10 years ago - submitted by Kristen Jensen

Core facility that supports the Diabetes Research Center affiliates by offering precise real time functional analysis of intact cells and primary tissue. The Cell Function Analysis Core also provides an islet isolation service, which gives affiliates easy access to primary tissue/cells ex vivo.

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• SciCrunch
• 10 years ago - submitted by Kristen Jensen

Core facility that provides specialized technical resources and expertise to enhance the efficiency, productivity and multidisciplinary nature of clinical research performed by Diabetes Research Center (DRC)-affiliated investigators.

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• SciCrunch
• 10 years ago - submitted by Kristen Jensen

University-affiliated center to support both basic and clinical research in diabetes and related metabolic disorders with the ultimate purpose of translating findings into opportunities to prevent these diseases and to improve clinical care and outcomes.

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• SciCrunch
• 10 years ago - submitted by Kristen Jensen

Core facility that provides Diabetes Research Center affiliates with access to specialized expertise and equipment required for high quality histochemical and morphological analyses in a cost-effective manner.

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• SciCrunch
• 10 years ago - submitted by Kristen Jensen

Core facility that supports the Diabetes Research Center in its primary mission to enhance research, education and training in diabetes, obesity and related disorders at the University of Washington and in the Greater Seattle area. The Core coordinates and manages programs, evaluates Center activities, and performs other duties.

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• SciCrunch
• 10 years ago - submitted by Kristen Jensen

Diabetes research center created to address the prevalence of diabetes and obesity. The goal of the center is to support and develop successful approaches to the prevention, treatment, and cure of diabetes mellitus and obesity.

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• SciCrunch
• 10 years ago - submitted by Kristen Jensen

Core which aims to develop and validate metabolomic methods and data analysis software and provide high quality routine metabolomic services. Its services include quantitation of selected water-soluble metabolites, fatty acids, and lipids, quantitation of metabolic fluxes using stable isotope tracers, and identification of novel metabolites involved in diabetes pathophysoiology.

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• SciCrunch
• 10 years ago - submitted by Kristen Jensen

Core which offers experiment planning, sample preparation, quality assessment, library construction, DNA sequencing, and data analysis services to DRC members. Its services also include RNAseq, microRNAseq, GroSeq, CLIP-seq, nucleosome mapping, ATAC-Seq, ChIPseq, Exome sequencing, whole genome and targeted methylome analysis, hydroxymethyl DIP, and single cell RNAseq.

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• SciCrunch
• 10 years ago - submitted by Kristen Jensen