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Core that aims to provide turnkey access to organoids/enteroid technologies to TMC-DDC researchers. These include samples (enteroids, organoids), reagents (specialized growth media, etc.), training, and consultative expertise. The core also provides access to gnotobiotic facilities and animals, training and consultative expertise.
Core facility whose services include histology, immunohistochemistry, RNA in situ hybridization, mRNA probe generation, frozen sections for enzyme histochemistry, immunofluorescent antibody studies, live and fixed cell confocal, deconvolution microscopy and super resolution microscopy (SIM and STORM), and transmission electron microscopy, quantitative morphometric analysis, high throughput microscopy and high content analysis, laser capture microdissection for molecular genetic analyses, and digital images for internet communication and publication.
Core that provides epidemiological and biostatistical support for design and analysis, and also provides investigators with access to the clinical specimens required for their basic and translational research activities. It offers assistance as well as didactic training in issues involving local and foreign IRB?s, HIPPA regulations, and importing or exporting clinical specimens.
Core that provides in vivo characterization of normal and pathophysiological mechanisms of hormonal and neural regulation of gastrointestinal (GI) function and brain-gut interactions in rodents to members and associate members of the CURE: DDRCC.
Collection of four cores: the biorepository core, for clinical specimen storage; the Histology/Imaging Core, for tissue preparation and sectioning; the Mouse Models Core, for education and training on various mouse modeling techniques; and the Clinical Component of the Administrative Core, for clinical study design consultation.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 15,2026. Core facility whose services include consultation about the challenges that Black Americans face regarding diet and food advertising, study design and implementation assistance, and positing relevant questions to the larger core for relevant research questions.
Core whose services include consultation in the choice of genomics methodologies to be applied to research problems being addressed by Digestive Diseases Center members, training in the conduct of functional genomics and metagenomics relevant to GI research, providing mammalian gene expression, cytokine/transcription factor/signaling pathway arrays, and gut microbial profiling/metagenomics to DDC members at discounted prices, and conducting periodic workshops and disseminating information about new technologies available in the Core and to obtain feedback on needed technologies / services.
Core whose aim is to promote and facilitate basic and translational GI research. Its services include consultation and troubleshooting in techniques for efficient gene delivery, as well as cloning and functional protein expression in mammalian cells in vitro and in vivo and consultation and to perform customized gene expression profiling, cytological phenotype profiling, and high-throughput molecular screening studies by utilizing high-throughput and highly automated robotic systems.
Center of collaborating research centers working on the research of digestive and liver-related diseases. Each center focuses on etiology, treatment, and prevention of digestive and/or liver diseases.
Core provides essential optical technologies and applications expertise to support faculty research by providing microscopic technology to all faculty members that facilitates their study of GI cellular signaling cascades, educating and training faculty members in the use of both basic and sophisticated cellular imaging methods, and developing and applying optical imaging technologies to GI tissues and cells based on faculty needs.
Center that is focused on what produces the digestive diseases that affect millions of people in the U.S., such as inflammatory bowel disease, hepatitis, metabolic syndromes and obesity.
Core facility which provides services through centralized resources and facilities, as well as training and assistance for the application of morphological, imaging and stem cell biology technologies and promoting collaborations among CURE:DDRCC investigators with independently-funded research projects.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 30,2023. Core facility that provides analytic support for a wide range of projects in diabetes translation research ranging from program evaluation to cost-effectiveness analysis.
Core facility whose services include secretory tests, motility and pH tests, videoendoscopy, biopsy and histology, serum bank of patients with ulcer hemorrhage, and visceral sensitivity and autonomic function tests.
Core facility whose services include consultation for management of complex datasets and literature resources, as well as promoting education of data analysis tools for researchers.
Management core which oversees the Vanderbilt University Medical Center Pilot and Feasability Program and promotes education, training, and outreach to the research community.
Research center for diabetes that offers regional and national resources to investigators for translation interventions into healthcare settings, communities, and populations at-risk. The CDTR supports studies investigating the root causes of diabetes and disparities as well as the prevention of obesity as a major contributing cause of Type 2 diabetes.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 15,2026. Core facility whose services include policy consultation and research design advice, workshops on systems science analysis, and management of a resource library of policy and system science tools and datasets.
Multidisciplinary program which aims to define fundamental mechanisms underlying Crohn?s disease and ulcerative colitis. It actively promotes clinical and translational research efforts to apply insights gained in studying various disease mechanisms through its five biomedical cores: the Human Genetics and Microbiome Core, the Morphology Core, the Immunology Core, the Genetic Animal Models Core and the Clinical Core.
Core that provides services in the utilization of advanced genetics and molecular biological techniques and facilitates the implementation of advances in genomics and molecular biology to IBD research. It provides access to capital or resource-intensive methodologies, such as laboratory automation cDNA and siRNA libraries, and BAC-centered recombinant DNA techniques.