SciCrunch

University of North Carolina Center for Gastrointestinal Biology and Disease

Center at UNC Chapel Hill and North Carolina State University for collaborative GI research. Its mission is to promote and enhance multidisciplinary digestive disease research.

Resource
SciCrunch
10 years ago - submitted by Isabella Froman

University of Michigan Center for Gastrointestinal Research Microbiome and Metabolomics Core

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 8,2025. Core whose services include consultation, Nucleic Acid Isolation, Microbiome (16S) Data Analysis, MiSeq-base 16S rRNA Gene Sequencing, Genomic/Metagenomic shotgun sequencing, Bacterial transcriptomics and metatranscriptomics, Multiplatform Metabolomic Profiling, Metabolomic sample preparation, and Germ-free & Gnotobiotic Mouse Facilities.

Resource
SciCrunch
10 years ago - submitted by Isabella Froman

University of Michigan Center for Gastrointestinal Research Molecular Biology Core

Core whose services include the following programs: Transgenic Rodent Program, Genome Editing Program, Viral Vector Program, and Integrated Genomics Program.

Resource
SciCrunch
10 years ago - submitted by Isabella Froman

University of Michigan Center for Gastrointestinal Research Protein Localization, Identification and Folding Core

Core facility whose services include the following programs: Imaging Core Program, Proteomics Core Program, Protein Folding Core Program, and Consultation.

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SciCrunch
10 years ago - submitted by Isabella Froman

University of Michigan Center for Gastrointestinal Research In Vivo Animal and Human Studies Core

Core facility that consists of the following 4 distinct programs: In Vivo Small Animal Studies Program, Organoid/Enteroid Modeling Program, Biospecimens Banking Service, and Clinical Design and Statistics.

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SciCrunch
10 years ago - submitted by Isabella Froman

University of Chicago Digestive Diseases Research Core Center Tissue and Cell Imaging Core

Core whose services include anatomic pathology review of human and experimental animal tissues as well as consultation in the best approaches for such analyses, cost-effective and high quality processing and staining of formalin-fixed paraffin-embedded tissues, and making collections of human tissue and imaging technologies available to researchers.

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SciCrunch
10 years ago - submitted by Isabella Froman

University of Chicago Digestive Diseases Research Core Center Integrated Translational Research Core

Core that serves as both a central repository for all the samples and data shared by the other cores and a catalyst for interdisciplinary research.

Resource
SciCrunch
10 years ago - submitted by Isabella Froman

University of Michigan Center for Gastrointestinal Research

Center whose goal is to investigate signal transduction mechanisms regulating homeostasis and GI disorders. Their approach includes studies on genetics and gene regulation, cellular signaling pathways, receptors and ion channels.

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SciCrunch
10 years ago - submitted by Isabella Froman

University of Chicago Digestive Diseases Research Core Center Tissue Engineering and Cell Models Core

Core that provides services such as a repository for intestinal cell lines, Tissue Engineering Models, experimental materials, and supplies for digestive disease research.

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SciCrunch
10 years ago - submitted by Isabella Froman

University of Chicago Digestive Diseases Research Core Center Host-Microbe Core

Core that consists of two components: The Enteric Microbiology and The Gnotobiotic Mouse components. The Enteric Microbiology component offers novel screening and advanced technologies for compositional and functional profiling of the resident microbial communities in the gastrointestinal tract. The Gnotobiotic Mouse component enables investigators to study the effects and causal role of specific microorganisms or profiles in vivo.

Resource
SciCrunch
10 years ago - submitted by Isabella Froman

University of Chicago Digestive Diseases Research Core Center Administrative Core

Core that has oversight of the other four cores of University of Chicago's Digestive Disease Research Core Center and determines the center's overall direction.

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SciCrunch
10 years ago - submitted by Isabella Froman

University of Chicago Digestive Diseases Research Core Center

Center whose goals include fostering collaboration among basic and clinical investigators, facilitating the use of new technologies in the study of treatment of digestive diseases, and providing education and training for improved treatment and diagnosis.

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SciCrunch
10 years ago - submitted by Isabella Froman

UCSF Liver Center Cell Biology Core

Core whose purpose is providing primary and immortalized liver cells for experimental use as well as other material such as human liver cells, primary hepatocytes, and immortalized cell lines.

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SciCrunch
10 years ago - submitted by Isabella Froman

UCSF Liver Center Pathology & Imaging Core

Core that provides services from routine liver histology to complex microscopy and image analysis.

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SciCrunch
10 years ago - submitted by Isabella Froman

UCSF Liver Center Clinical & Translational Core

Core that supports study design to sample procurement and storage, to data analysis and presentation, and also focuses on research involving human subjects.

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SciCrunch
10 years ago - submitted by Isabella Froman

Hopkins Conte Digestive Diseases Basic and Translational Research Core Center Proteomics Core

Core facility that uses mass spectrometry coupled to one (1D) and two (2D) dimensional separations by column chromatography or gel electrophoresis to identify, quantify or characterize proteins and their post-translational modifications, that are expressed in well characterized protein fractions from the small intestine, colon, kidney, liver and pancreas. Techniques such as difference gel electrophoresis (DIGE), isobaric tag for relative and absolute quantitation (iTRAQ), tandem mass tags (TMT) and stable isotope labeling of amino acids in cell culture (SILAC) as well as non-labeling methods (MudPIT, multi-dimensional protein identification technology) are available for quantifying relative differences in protein expression and post-translational modifications, such as acetylation, glycosylation, phosphorylation, nitrosation, ubiquitination and novel cleavage sites.

Resource
SciCrunch
10 years ago - submitted by Isabella Froman

UCSF Liver Center Immunology Core

Core that takes advantage of local expertise and resources to enable Center members to analyze cell populations in mouse or human livers. It performs complex analyses on small numbers of human cells, such as those obtained from liver biopsies.

Resource
SciCrunch
10 years ago - submitted by Isabella Froman

UCSF Liver Center

Center whose goal is to integrate bench science with clinical investigation, in support of its vision to understand and cure human liver diseases.

Resource
SciCrunch
10 years ago - submitted by Isabella Froman

Hopkins Conte Digestive Diseases Basic and Translational Research Core Center Translational Research Enhancement Core

Core facility whose services include establishing Best Practices (BP) and uniform Standard Operating Procedures (SOPs) for the collection, annotation, processing, storage, management, distribution, and ethical use of human specimens, and to provide access to specimens by investigators as well as patient identification, patient recruitment, facilitation of patient trials, translational research and basic research through creation of a patient registry and database.

Resource
SciCrunch
10 years ago - submitted by Isabella Froman

Hopkins Conte Digestive Diseases Basic and Translational Research Core Center Image Core

Core facility that provides state-of-art light microscopy technology to the members of the Hopkins Basic Research Digestive Disease Development Center and to the whole Hopkins scientific community.

Resource
SciCrunch
10 years ago - submitted by Isabella Froman

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