We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Software toolbox which finds and displays temporal relations amongst components. This can help determine causal relations in the brain.
Database of RNA-seq gene expression in hippocampal principal neurons. Hipposeq can analyze and visualize RNA-seq data for all excitatory cell populations in the hippocampus at multiple levels of granularity.
Software package to analyze oligonucleotide arrays (expression/SNP/tiling/exon) at probe-level. It currently supports Affymetrix (CEL files) and NimbleGen arrays (XYS files).
The ICR mouse is a strain of albino mice originating in Switzerland and selected by Dr. Hauschka to create a fertile mouse line.
Software code for bisulfite sequencing virus integration. This finder is for directional libraries only and does not support PBAT and indirectional libraries.
Repository of matlab code for reconstruction and analysis of effective connectivity in vitro.
Software used in tandem with the Polygon 400 from Mightex systems to define areas of illumination, control light intensity and duration, and calibrate the device.
Database of mouse brain cell type-specific gene expression datasets. NeuroExpresso is able to demonstrate the use of marker genes for acquiring cell type specific information from whole tissue expression.
Web application for designing gRNAs for CRISPR/Cas9 experiments. It selects target sites for CRISPR/Cas9, CRISPR/Cpf1 or TALEN-directed mutagenesis.
Statistical analysis program that performs linear and nonlinear regression analysis as well as surface and curve fitting. NLREG can handle linear, polynomial, exponential, logistic, periodic, and general nonlinear functions.
Portal with detailed information about various research centers that focus on pediatric medicine and nephrology. These centers are funded by NIDDK.
Image analysis software package that allows non-destructive image marking, input for further image processing, and marking the results of automatic measurements. Object-Image integrates measurements, macros, graphical objects and image names in a closed unit called 'object file' so that it reduces file clutter.
Database of neuronal cell types based on multimodal characterization of single cells to enable data-driven approaches to classification.
Software package for classification and regression based on a forest of trees using random inputs.
Source code for a machine learning method to detect somas on confocal microscopic images of the Drosophila brain. The method can be applied to the original raw images where the noises are not removed and the number of somas is unknown.
Database of disease genes and risk factors and of host pathogen/interactomes. Lists genes, pathways and environmental risk factors positively associated with diseases and conditions such as Alzheimer's disease, schizophrenia, multiple sclerosis, childhood obesity, anorexia nervosa, HIV-1/AIDS, and helicobacter pylori. Details of polymorphisms as well as negative/positive association data can be found via Useful links. Throughout the site are links to Entrez Gene and Pubmed.
Web application that scans a library of protein-DNA complexes and builds comparative models of proteins bound to DNA. Its results include complex coordinates, schematic interface diagrams, interface alignments and DNA motifs.
Web application for the design of PCR primers for cross-species amplification of novel sequences from metagenomic DNA or from uncharacterized organisms belonging to user-specified phylogenetic lineages. It implements an extended CODEHOP strategy and evaluates thermodynamic properties of the oligonucleotide pairs.
Database of DNA-binding protein structures that is updated with Protein Data Bank complexes. It provides structure-based binding specificities and sequence logos, classification and clusters of protein-DNA interfaces, and downloads/stats.
Web application for structural alignment of DNA motifs and protein domains from DNA binding protein complexes in Protein Data Bank.