Curator Dashboard

Core whose purpose is providing primary and immortalized liver cells for experimental use as well as other material such as human liver cells, primary hepatocytes, and immortalized cell lines.

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• SciCrunch
• 9 years ago - submitted by Isabella Froman

Core that provides services from routine liver histology to complex microscopy and image analysis.

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• SciCrunch
• 9 years ago - submitted by Isabella Froman

Core that supports study design to sample procurement and storage, to data analysis and presentation, and also focuses on research involving human subjects.

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• SciCrunch
• 9 years ago - submitted by Isabella Froman

Core facility that uses mass spectrometry coupled to one (1D) and two (2D) dimensional separations by column chromatography or gel electrophoresis to identify, quantify or characterize proteins and their post-translational modifications, that are expressed in well characterized protein fractions from the small intestine, colon, kidney, liver and pancreas. Techniques such as difference gel electrophoresis (DIGE), isobaric tag for relative and absolute quantitation (iTRAQ), tandem mass tags (TMT) and stable isotope labeling of amino acids in cell culture (SILAC) as well as non-labeling methods (MudPIT, multi-dimensional protein identification technology) are available for quantifying relative differences in protein expression and post-translational modifications, such as acetylation, glycosylation, phosphorylation, nitrosation, ubiquitination and novel cleavage sites.

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• SciCrunch
• 9 years ago - submitted by Isabella Froman

Core that takes advantage of local expertise and resources to enable Center members to analyze cell populations in mouse or human livers. It performs complex analyses on small numbers of human cells, such as those obtained from liver biopsies.

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• SciCrunch
• 9 years ago - submitted by Isabella Froman

Center whose goal is to integrate bench science with clinical investigation, in support of its vision to understand and cure human liver diseases.

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• SciCrunch
• 9 years ago - submitted by Isabella Froman

Core facility whose services include establishing Best Practices (BP) and uniform Standard Operating Procedures (SOPs) for the collection, annotation, processing, storage, management, distribution, and ethical use of human specimens, and to provide access to specimens by investigators as well as patient identification, patient recruitment, facilitation of patient trials, translational research and basic research through creation of a patient registry and database.

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• SciCrunch
• 9 years ago - submitted by Isabella Froman

Core facility that provides state-of-art light microscopy technology to the members of the Hopkins Basic Research Digestive Disease Development Center and to the whole Hopkins scientific community.

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• SciCrunch
• 9 years ago - submitted by Isabella Froman

Core facility that supports basic, translational, and clinical research in the digestive diseases by providing access to human materials and resources in statistics and study design. Its services promote translation of basic research advances into improved clinical care by offering fresh and archived human specimens, associated clinical metadata, biostatistics and aid in study design.

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• SciCrunch
• 9 years ago - submitted by Isabella Froman

Core facility that provides Center investigators and their laboratories the tools and advice needed to establish and study mouse (including transgenic and knockout) and human (i.e. GI organoids) physiology of GI disease.

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• SciCrunch
• 9 years ago - submitted by Isabella Froman

Core facility that supports basic, translational, and clinical research in the digestive diseases by providing access to human materials and resources in statistics and study design. It also aims to to forge connections and support collaboration between HDDC Clinical Associates and Members, support a well-organized infrastructure for acquisition and storage of clinical samples, and provide professional support in biostatistics and study design to HDDC members and Clinical Associates.

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• SciCrunch
• 9 years ago - submitted by Isabella Froman

Center that aims to advance basic science and translational digestive diseases research at the Johns Hopkins University School of Medicine. Its goal is to improve the health of patients with the broad spectrum of gastrointestinal and hepatic disorders.

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• SciCrunch
• 9 years ago - submitted by Isabella Froman

Core facility that provides the infrastructure, biologic resources, expertise, and training for cross-disciplinary research on epithelial biology and immune function in mucosal surfaces and solid organs of the GI tract.

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• SciCrunch
• 9 years ago - submitted by Isabella Froman

Community of scientists focused on the study of epithelial cell function and mucosal biology including inflammation and host defense of the gastrointestinal tract. It focuses on the intestinal and inflammatory bowel diseases; gut microbiology; and stem cell and developmental biology of the intestine and liver in organ physiology, regenerative medicine, and metabolism.

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• SciCrunch
• 9 years ago - submitted by Isabella Froman

Provides human microbiome datasets and minimum reporting standards established by DCC, from both initial HMP-1 phase and iHMP. Offers to query and retrieve metagenomic, metatranscriptomic, human genetic, microbial culture, and many other data types from each project. Provides integrated longitudinal datasets from both microbiome and host from different cohort studies of microbiome associated conditions.

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• dkNET
• 9 years ago - submitted by Ko-Wei Lin

Software tool which allows the automatic and high throughput measure of root length, as well as extra associated measures such as curvature. The user must supply start points for each root, and exemplar patches of nearby background. The software will then trace the main root to the tip, in every image in a timeseries, and record the results.

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• SciCrunch
• 9 years ago - by Anonymous

Software tool for quantification of root system architectures in range of plant species, grown and imaged in variety of ways. Root phenotyping software driven by deep learning. Measurements can be exported directly in RSML format, where additional traits can be calculated later using simple plug-in system.

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• SciCrunch
• 9 years ago - by Anonymous

Modular program for SPM (scanning probe microscopy) data visualization and analysis. Primarily it is intended for the analysis of height fields obtained by scanning probe microscopy techniques (AFM, MFM, STM, SNOM/NSOM) and it supports a lot of SPM data formats. However, it can be used for general height field and (greyscale) image processing, for instance for the analysis of profilometry data or thickness maps from imaging spectrophotometry.

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• RRID-Legacy
• 9 years ago - by Anonymous

European project that aims to improve the care for patients with Traumatic Brain Injury. It provides general information and aims to be a communication platform for patients, scientific participants and investigators.

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• RRID-Legacy
• 9 years ago - by Anonymous

Ontology of drug targets to be used as a reference for drug targets, with the longer-term goal of creating a community standard that will facilitate the integration of diverse drug discovery information from numerous heterogeneous resources. The project itself aims to develop a novel semantic framework to formalize knowledge about drug targets with a focus on the current IDG protein families.

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• SciCrunch
• 9 years ago - submitted by Anita Bandrowski