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Online genome annotation tool for validating and correcting gene annotations. OrcAE is community-driven and can be edited by account-holders in the research community.
Online database documenting the genome of the Japanese lamprey. The project uses the genome to gain insight into the evolution of vertebrate organisms.
Database project to document the genome sequence of the Lancelet, a basal extant chordate. Information provided includes reference haploid genome sequence and annotation data, gene models and function, and integrated information from diploid genome sequence and annotation data.
Integrated platform that serves as a central resource for rare disease research databases, registries, biobanks and clinical bioinformatics. The RD-CONNECT project utilizes researcher cooperation and data sharing to improve research methods and further scientific understanding of rare diseases.
High-throughput sequencing machine which enables sequencing of exomes, whole genomes, and transcriptomes. It also provides flow cell types, real-time analysis, and integration with Illumina's BaseSpace computing environment.
Data aggregate that compiles results from bioinformatics analyses across multiple samples into a single report. It is written in Python.
Software implementing a method for assessing both the algorithmic and statistical reliability of estimated independent components developed by Himburg et al in their 2004 paper. The method is based on running the ICA algorithm many times with slightly different conditions and visualizing the clustering structure of the obtained components in the signal space. In experiments with magnetoencephalographic (MEG) and functional magnetic resonance imaging (fMRI) data, the method was able to show that expected components are reliable; furthermore, it pointed out components whose interpretation was not obvious but whose reliability should incite the experimenter to investigate the underlying technical or physical phenomena.
Data analysis, graphing, and management application that allows users to import, manipulate, analyze data, and create customized plots. Plots include x-y probability, histogram, box, percentile, horizontal bar, stack bar, column, stack column, polar, and pie. Binned data can be exported to a histogram, step plot, or spike plot. KaleidaGraph works with Windows and Macintosh systems., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Text mining software that searches curated molecular pathway and cell interaction libraries.
Commercial antibody supplier which provides a web-accessible database of reference and applications data with their reagents.
Group Sparse Canonical Correlation Analysis is a method designed to study the mutual relationship between two different types of data.
Website resource for researchers to order and send Drosophilia specimens to each other. This community-driven supplier also works with the FlyBase Drosophilia database to search for synonyms for fly species.
Modeling and simulation environment for study of multi scale and multicellular systems. Users can construct and simulate models of gene regulation, signaling pathways, tissue patterning and morphogenesis and explore the effects of multiscale feedbacks between these processes. Morpheus can render 2D and 3D models using graphical user interface.
Data analysis tool that utilizes the Comparative CT (ddCT) method to rapidly and accurately quantitate relative gene expression across a large number of genes and samples. Raw input from plates or arrays can be analyzed according to user-determined settings.
Genomics knowledgebase for clinical relevance of genes and variants for use in research. ClinGen's primary function is to store and share information for the benefit of the scientific community. Laboratory scientists, clinicians, and patients can share and access data.
Interoperability framework which supports integrative genomics analysis via access to various bioinformatics tools. Rather than performing analyses itself, GenomeSpace acts as a hub for data from supported bioinformatics tools and reformats data and results when necessary.
Human and mouse genome annotation project which aims to identify all gene features in the human genome using computational analysis, manual annotation, and experimental validation.
Semi-automated and manually curated database of gene/variant annotations, therapy knowledge, diagnostic/prognostic information, and oncology clinical trials. Users can search CKB via gene, gene variants, drug, drug class, indication, and clinical trials.
Database that aggregates exome and genome sequencing data from large-scale sequencing projects. The gnomAD data set contains individuals sequenced using multiple exome capture methods and sequencing chemistries. Raw data from the projects have been reprocessed through the same pipeline, and jointly variant-called to increase consistency across projects.
Software that automatically reads and processes up to 100 raw microarray image files. The software finds and places microarray grids, rejects outlier pixels, accurately determines feature intensities and ratios, flags outlier pixels, and calculates statistical confidences.