Curator Dashboard

Departamental portal of Applied Biochemistry, School of Engineering, Tokai University, Japan. Used for computed tomography (CT) and visualizing 3D structures of biological soft tissues represented with Cartesian coordinates.

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• SciCrunch
• 8 years ago - by Anonymous

Positioner for automated rotation of a head-fixed rodent specimen about the anterior-posterior and medio-lateral axes for imaging or other purposes. Provides automated Z translation and can be customized to accommodate various head bar designs.

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• SciCrunch
• 8 years ago - submitted by Boaz Mohar

Software tool for analysis of large 16S rRNA pyrosequences by using a consensus alignment algorithm, utilizing the sequence redundancy of abundant species in the pyrosequence dataset.

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• RRID-Legacy
• 8 years ago - submitted by Kate Kennedy

This is a zebrafish that knock out ponli by CRISPR/cas9.It lacks 4 amino acids.We use it to analyze its phenotype and study its internal pathological changes.

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• SciCrunch
• 8 years ago - submitted by 翁 科超

This is a fish that knock out crb2b by CRISPR/cas9.It lacks 5 amino acids.We use it to analyze its phenotype and study its internal pathological changes.

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• SciCrunch
• 8 years ago - submitted by 翁 科超

Recombinant mouse Osteolectin protein purified from supernatant of 293 cells overexpressing 3'Flag-tagged mouse Osteolectin (PMID: 27976999)

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• SciCrunch
• 8 years ago - submitted by Bo Shen

Recombinant human Osteolectin protein purified from supernatant of 293 cells overexpressing 3'Flag-tagged human Osteolectin (PMID: 27976999)

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• SciCrunch
• 8 years ago - submitted by Bo Shen

Scanner for microarray analysis to scan next-generation higher-density arrays, including SNP arrays, tiling arrays for transcription and all-exon arrays for whole-genome analysis.

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• RRID-Legacy
• 8 years ago - submitted by Thai Tran

Ay and other mutations at the a locus conferring a completely yellow coat color are dominant to all a alleles that produce a darker coat. Hair pigment of Ay heterozygotes is yellow, but eyes are black. Heterozygotes usually become obese and infertile within a few months after birth. Increased adipose tissue mass is due to fat cell hypertrophy, and it has been hypothesized that the obesity results from the observed reduction in hypothalamic norepinephrine and dopamine. Heterozygotes are more susceptible to several kinds of tumors than are normal mice, possibly due, at least in part, to a general increase in cell proliferation that also manifests as a slight increase in lean body mass and skeletal length. Further spleen cells from heterozygotes cause a significantly lower graft vs. host reaction. Mice homozygous for the yellow spontaneous mutation (Ay) die before implantation, or shortly thereafter. The time of death and type of abnormality is, in part, determined by the genetic background on which the mutation is placed. Mice of the KK strain develop diabetes of polygenic origin, and mice of other strains heterozygous for Ay become obese and mildly diabetic. KK.Cg-Ay/J heterozygotes develop hyperglycemia, hyperinsulinemia, glucose intolerance and obesity by eight weeks of age. Studies using isolated adipocytes indicate that tissue responsiveness to insulin is decreased. Histo- and immunocytochemical studies show that the pancreatic islets are hypertrophied and the β-cells are degranulated. These findings suggest that the principal cause of diabetes in these mice is insulin resistance. Body composition analysis shows that both the fat and lean tissue mass are increased compared to non-obese mice, with fat accounting for 30-35% of total body weight. The pleiotropic mutant phenotype of Ay/a mice is attributed to ectopic expression of the agouti protein, while the early embryonic lethality of the Ay mutation in the homozygous state is assumed to result from lack of expression of the Raly gene product (Bultman et al. 1992, Miller et al. 1993, Duhl et al. 1994, Michaud et al. 1993, 1994). That ectopic expression of the agouti protein is probably responsible for the non-lethal aspects of this mutation has been demonstrated by transgenic expression of the protein from a ubiquitous promoter (Klebig et al. 1995, Perry et al. 1995).

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• RRID-Legacy
• 8 years ago - submitted by Thai Tran

The GeneChip Scanner 3000 7G is an extension of the GeneChip Scanner 3000 (GCS 3000) series that allows you to scan next-generation higher-density arrays, including SNP arrays with up to 900,000 SNPs, tiling arrays for transcription and all-exon arrays for whole-genome analysis. The GCS 3000 7G combines space-saving and other design improvements with speed, superior performance and lower scanner-to-scanner variation to dramatically improve throughput and efficiency in your genetic analysis. The GCS 3000 7G also provides enhanced auto-focus and more consistent scanner-to-scanner biological performance to improve data integrity and data sharing between researchers. In addition the GCS 3000 7G has been designed to accommodate future advancements in GeneChip probe array technology. Combined with the GeneChip AutoLoader, the GCS 3000 7G provides sample tracking, temperature control and walk-away freedom from scanning. This scanner is sold with a powerful computer workstation with quad-core Xeon processor loaded with Affymetrix GeneChip Command Console Software (AGCC).

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• RRID-Legacy
• 8 years ago - submitted by Thai Tran

Software tool for microarray analysis designed for biologists . Used for identification of differential expression by providing interactive visualizations.

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• RRID-Legacy
• 8 years ago - submitted by Thai Tran

GeneChip™ WT Sense Target Labeling and Control Reagents (900652) and GeneChip WT cDNA Synthesis and Amplification Kits (900672 and 900673) are being discontinued in June 2010. The Whole Transcript (WT) Sense Target Labeling Assay has an updated protocol. The GeneChip WT (Whole Transcript) Terminal Labeling Kit is optimized to be used for the fragmentation and labeling steps of the GeneChip WT Sense Target (ST) Labeling Assay. The WT Terminal Labeling Kit employs a strategy for reproducible DNA fragmentation with a combination of uracil DNA glycosylase (UDG) and apurinic/apyrimidinic endonuclease 1 (APE 1). The typical input material is random-primed, single-stranded DNA Following fragmentation, the resulting fragmented DNA can then be labeled using terminal deoxynucleotidyl transferase (TdT) in the presence of a proprietary biotinylated compound, GeneChip DNA Labeling Reagent. Both components are also provided in the WT Terminal Labeling Kit. The final labeled DNA target is ready to be added to the cocktail for hybridizing to the arrays such as the GeneChip Human Exon 1.0 ST Array.

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• RRID-Legacy
• 8 years ago - submitted by Thai Tran

Spectrophotometer for measurement and analysis of 1 ul samples with high accuracy and reproducibility. Full spectrum from 220nm to 750nm spectrophotometer utilizes patented sample retention technology that employs surface tension alone to hold sample in place. No need for cuvettes. Has capability to measure highly concentrated samples without dilution.

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• RRID-Legacy
• 8 years ago - submitted by Thai Tran

The RNeasy Mini Kit provides fast purification of high-quality RNA from cells, tissues, and yeast using silica-membrane RNeasy spin columns with a binding capacity of 100 μg RNA. Tissue samples can be conveniently stabilized using RNAlater RNA Stabilization Reagent or Allprotect Tissue Reagent, and efficiently disrupted using a TissueRuptor or TissueLyser system. RNA purification using the RNeasy Mini Kit can be fully automated on the QIAcube. For smaller and larger samples, the RNeasy Micro Kit (spin-column binding capacity of up to 45 µg RNA), the RNeasy Midi Kit (spin-column binding capacity of 1 mg RNA), and RNeasy Maxi Kit (spin-column binding capacity of 6 mg RNA) are also available.

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• RRID-Legacy
• 8 years ago - submitted by Thai Tran

It is nutrient food for feeding mice within quantification of the chemical composition, depends on the purpose of the designed experiments.

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• RRID-Legacy
• 8 years ago - submitted by Thai Tran

Software tool as an annotated database of protein phosphorylation sites in eukaryotes. Contains experimentally identified and conserved p-sites which were collected from phosphoproteomic studies.

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• RRID-Legacy
• 8 years ago - submitted by Shaofeng Lin

Platform for publishing reproducible code and datasets and providing access to national supercomputers, private clouds, and institutional high-performance computer systems to promote open software and data sharing to advance understanding of the human brain.

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• NIF
• 8 years ago - submitted by Matt Travers

University service for testing behaviour of rodents. Provides facilities and training for researchers to conduct experiments themselves within the core facility.

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• SciCrunch
• 8 years ago - by Anonymous

Modular platform for performing two‐photon laser scanning microscopy (TPLSM) optimized for in vivo applications.

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• SciCrunch
• 8 years ago - by Anonymous

Software tool to search for the targets of annotated miRNAs based on microT-CDS algorithm.

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• RRID-Legacy
• 8 years ago - by Anonymous