Curator Dashboard

Core provides services for generation and characterization of induced pluripotent stem cells (iPSCs) from somatic sources such as blood and fibroblasts, along with long-term cryobanking. Offers access to collection of well-characterized iPSC lines derived from both healthy donors and patients with various diseases, representing a range of ethnic backgrounds and sexes.Major focus of core is gene editing in pluripotent stem cells, with expertise in CRISPR-based applications from precise point mutation knock-in (correction or introduction) to the generation of reporter lines (e.g., GFP and other fluorescent reporters) and inducible systems such as Cre-lox, dTAG, and beyond.Core provides guidance and support for the differentiation of iPSCs into multiple cell types, using both monolayer and 3D organoid formats, enabling downstream disease modeling and functional studies.

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• SciCrunch
• 10 months ago - submitted by Edyta Vieth

Visualization software tool for viewing large image files in a browser. Works with Brain Image Library, built for BICAN.

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• 11 months ago - submitted by Anita Bandrowski

Procures high-quality biologic specimens along with coded clinical and demographic data across broad ethnic, racial, and social demographic of patients. All specimens are systematically collected and processed so that their multi-functional potential for recovering high-quality bioanalytes (including RNA, genomic DNA, protein, enzymes and metabolites) is conserved. All specimens are stored and protected in a database hub to connect researchers conducting variety of scientific projects across multiple medical specialties. Muilti-disciplinary biorepository with capacity for generating specialized bioanalytes.

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• 11 months ago - by Anonymous

Instrument used to quantify biomolecular interactions and measure their binding affinity using MicroScale Thermophoresis. Can determine the strength of binding between all types of biomolecules, from single ions to large complexes, in various complex samples and buffer conditions.

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• 11 months ago - submitted by Edyta Vieth

Software R package for fully Bayesian inference of tumor microenvironment composition and gene expression deconvolution. Used to analyze bulk RNA-seq data and estimate cell type-specific expression profiles.

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• 11 months ago - submitted by Zehua Chen

Core provides centralized service for generating AAV particles for cardiovascular studies. The CCDS Virus Production Core offers the production of either pre-made (ex. AAV8-GFP, AAV8 mPCSK9 D377Y) or custom AAVs.

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• SciCrunch
• 11 months ago - submitted by Edyta Vieth

Core provides centralized service for performing technically challenging mouse models of cardiovascular disease, such as middle cerebral artery occlusion (MCAO) stroke model, coronary artery ligation model of myocardial ischemia, femoral artery ligation model of peripheral artery disease, and partial carotid artery ligation model of disturbed blood flow.

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• SciCrunch
• 11 months ago - submitted by Edyta Vieth

Software R package for performing weighted gene co-expression network analysis in high dimensional transcriptomics data such as single-cell RNA-seq or spatial transcriptomics.

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• 11 months ago - by Anonymous

Core to serve academic and industry researchers in their studies on the function and structure of genomes. Offers services for next-generation Illumina sequencing, 10X single-cell library preparation, Sanger sequencing, fragment analysis and nucleic acid quantification and sizing.

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• 11 months ago - submitted by Andrew Gorzalski

Small foundation and think tank that seeks to equip brilliant scientists with leading technology, crucial collaborators and cutting-edge support to accelerate discoveries — transforming bold ideas into breakthroughs in metabolism.

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• 11 months ago - by Anonymous

Core offers bioinformatics and data modeling services. Focuses on support for reproducible, well documented, containerized, nextflow pipelines customized to address the specific research questions and biological systems of the investigators. Offers support from preprocessing -omics data, through data integration and manuscript support, based on grant support or a fee-for-service mechanism. Provides training for students and PIs in the form of individual help, seminars, and workshops.

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• SciCrunch
• 11 months ago - submitted by Edyta Vieth

University of Northampton is public university based in Northampton, which offers students undergraduate and postgraduate courses. It was formed in 1975 as Nene College of Higher Education.

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• 11 months ago - submitted by Edyta Vieth

Software application that predicts bacteriophage gene functions by leveraging gene synteny and genome-wide organizational patterns. Synteny-enhanced annotation of Bacteriophage genes.

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• 11 months ago - submitted by Susie Grigson

Core offers instrumentation and support for the structural characterization of biological macromolecules to investigators at Mayo Clinic and its partner institutions. Supports cryogenic sample electron microscopy (cryoEM), along with associated services such as training, data collection, processing, analysis, and data storage. Future services will include nuclear magnetic resonance (NMR) spectroscopy and X-ray crystallography.

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• SciCrunch
• 11 months ago - submitted by Edyta Vieth

Electrophysiological Test Unit for animals. This is usable for Pattern VEP + Pattern ERG + Flash VEP, for scotopic and photopic ERG, EOG fast and slow, mf ERG Flash stimulation and mf VEP Pattern stimulation.

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• 11 months ago - by Anonymous

Reporting to the Division of Information Technology, and working in close partnership with the Office of Research, works with researchers to improve their project performance and secure computing resources not only at the university level but beyond, to National Labs and other high profile HPC resources.

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• 11 months ago - submitted by David Reddy

Multidisciplinary facility designed to explore questions related to human behaviour from various perspectives, including human cognition, social interactions, and psychophysiology.

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• 11 months ago - by Anonymous

Transmission electron microscope developed for the fields of biology and materials science. Equipped with a highly sensitive CCD camera, the H-7650 delivers images with optimal contrast even under low-dose electron beam conditions. As the CCD camera is integrated into the microscope, it can be controlled either manually via the control panel or through a PC. Images displayed on the monitor can be stored in digital formats. With built-in autofocus, other automated functions, and database capabilities, the H-7650 provides users with a user-friendly operating environment during observation.

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• 11 months ago - by Anonymous

Software R package that enables cross-platform import, export, and sharing of gated cytometry data. It currently supports Cytobank, FlowJo, Diva, and R, allowing users to import gated cytometry data from commercial platforms into R.

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• RRID
• 11 months ago - by Anonymous

Software application to perform Bayesian analysis on expression and gene dependency data across different cell lineages. Integrates expression as the dependent variable and gene dependency data as the independent variable. Used to identify cancer gene targets by jointly analyzing global transcriptomic and proteomic profiles with genetic dependency data of cancer cell lines across tissue lineages.

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• 11 months ago - submitted by Abdulkadir Elmas