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Core can generate custom monoclonal antibodies in mouse and hamster systems. Can also produce large amounts of antibodies (of all species) and recombinant proteins in-vitro. Purification is also available for various systems.
Core offers a fully functional tissue culture facility with specialized instruments, media, reagents, cell lines, and expertise for new or established researchers to perform cutting-edge stem cell research. In addition, our core provides comprehensive human induced pluripotent stem (iPS) cells related training, consultations, and standard and customized scientific services, including derivation of iPS cells, differentiation of iPS cells and genome editing in iPS cells to stem cell researchers.
Provides expert advice and guidance for collaborative research projects involving the use of fluorescence and electron microscopy. Access to advanced fluorescence and electron microscopes for external users after a peer-review process.
Core provides mass-spectrometry solutions for small-molecule research. Supports experimental design, ensuring proper handling, appropriate controls, and adequate statistical power, and then executes analyses on Thermo Orbitrap IQ-X and Agilent 6495D LC/MS systems and an Agilent 5977C GC/MS system. Using validated methods annotated against a library of 1,000+ compounds, we maximize metabolite and small-molecule coverage. We also offer untargeted profiling for biomarker and novel metabolite and lipid discovery, as well as stable-isotope tracing for measuring substrate utilization. Results are delivered with custom informatics and statistical interpretation for faster, more approachable insights.
Software tool for extracting information from scholarly documents.
Software suite of tools designed to build information services for developing regions.
Core offers services in Analytical Flow Cytometry, Fluorescence Activated Cell Sorting, consultation and data analysis. Staff provides training, assisted acquisition, consultation, and data analysis upon request.
Core provides biospecimen processing and performs automated slide-based biomarker methods (protein/RNA/DNA), implementing good clinical laboratory practices.Offers specialized consultation and perform biomarker development and analyses within clinical study and research program protocols.Provides services to the clinical trials and pre-clinical research community and expertise in biomarker selection, method development, optimization and standardization, and provision of quality consultation on biomarkers for clinical research protocols.
Core offers services in optical microscopy experiments including: confocal, multiphoton, super-resolution, FRAP, FRET, live-cell timelapse, whole-slide scanning, image analysis and more.
Artificial Social Agent Questionnaire (ASAQ), an instrument for evaluating human interaction with an artificial social agent (ASA), resulted from multi-year efforts involving more than 100 Intelligent Virtual Agent (IVA) researchers worldwide within the OSF work-group of Artificial Social Agent Evaluation Instrument (https://osf.io/6duf7/). It has 19 measurement constructs constituted by 90 items, which capture more than 80% of the constructs identified in empirical studies published in the IVA conference 2013-2018. In addition, a representative item of each construct or dimension was selected to create a 24-item short version of the ASA questionnaire. Whereas the long version is suitable for a comprehensive evaluation of human-ASA interaction, the short version allows quick analysis and description of the interaction with the ASA.
public research and teaching hospital network in Toronto, Ontario, Canada. It is affiliated with the Temerty Faculty of Medicine at the University of Toronto, and is the largest health research organization in Canada, ranking first in the country for total research funding.
Core provides services including Basic High-Throughput Sequencing Analysis, Advanced Data Analysis, High Performance Computing.
Offers services to support studies in medical fields across oncology, cardiology, metabolic diseases, radiotheranostics and more.Helps with study design to final data analysis, including GLP-compliant histopathology services.
Core provides services for the use of patient-Derived tumor Organoid (PDO) model.Organoid models are derived from patient-derived xenograft tissues, primary tumors, and metastatic patient tissues. PMLB organoid repository includes models generated from colorectal, pancreatic, and lung cancer tissues.
Core offers cell sorting and flow cytometry services. Provided instruments include BD FACS Canto II, Beckman Cytoflex LX, BD FACS ARIA III, AutoMacs Cell Separator.
Core offers services including Study planning and design; Grant writing and protocol creation; Data collection form design; Data capture instrument construction; Complex data processing and linkage; Quality control involvement; Statistical analysis, figure, and table generation; Manuscript drafting and presentation preparation; Response to manuscript reviews from regulatory agencies and journals.
Provides testing and analysis support for clinical trials to improve consistency and reliability in clinical trial data.Helps clinical investigators achieve systematic image collection and improved collaboration. Can help with handling large volume functional and dynamic imaging data.
Facility provides analytical flow cytometers and high-speed cell sorting, as well as training, education and consultation services.
AMDL is a clinical CAP/CLIA accredited molecular diagnostics laboratory at the Princess Margaret Cancer Centre. Supports clinical trials and translational research projects requiring clinical-grade (CAP/CLIA) molecular testing at Princess Margaret Cancer Centre. AMDL works closely with Molecular Diagnostics lab in Toronto General Hospital to transition protocols into clinical tests.
Core is dedicated to providing access to cost-effective and high quality genomics services including standard and custom-tailored DNA sequencing using Illumina technologies, epigenomics, panel-based profiling (Luminex and Nanostring) and functional genomics. Single cell genomics applications on variety of popular platforms.