Curator Dashboard

Facility provides integrated synthetic and analytical capabilities for biological materials, including proteins, peptides, and nanoparticles, range of technical expertise and instrumentation. Access is available to all members of MIT community. Priority access is given to KI members, NCI-funded research projects and other contributing user groups in recognition of funding support. In special circumstances, access may be available to non-MIT users.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Provides central location for flow cytometry instrumentation and education. Services include Flow Cytometry,Cell sorting, data analysis, training. Software packages to analyze data include ModFit LT, BD FACSDiva v6, Cell Quest Pro, and FlowJo vX, from facility workstations.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Provides servies in mass spectrometry, proteomics, metabolomics and lipidomics. Services include Thermo Orbitrap Elite and Thermo QExactive HF Orbitrap microcapillary LC-MS/MS:Protein identification, Post-translational modification site mapping,Relative quantification: Label-free, SILAC, TMT, etc.;AB/SCIEX 5500 QTRAP LC-MS/MS:Polar metabolomics profiling,13C/15N metabolic flux analysis;Thermo QExactive Plus/HF Orbitrap LC-MS/MS:Untargeted Lipidomics profiling, Untargeted Metabolomics Profiling.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Provides evolutionary and computational biology investigators with computing and large data storage capacity for use in analyzing and managing large volumes of research data. Core contains advanced mix of high performance computing clusters, servers and data storage components, knowledge and technical skills required to compress years of analysis into days.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Provides advanced instrumentation for researchers interested in investigating biological processes at cellular, sub cellular and molecular level.Instrumentation include Confocal Microscope Systems :Zeiss LSM-510 Meta Confocal Microscope, Olympus FV1000 MPE Basic Multiphoton Microscope;Brightfield/Fluorescence: Nikon Eclipse TE300 (inverted) Fluorescent Microscope, Nikon Eclipse 80i (upright) Fluorescent Microscope, Leica Thunder Imager; TIRF Systems:Olympus TIRF Microscope; Transmission Electron Microscopy:Hitachi 7500 TEM, RCM MTX Ultramicrotomes;Scanning Electron Microscopy:Hitachi 4700 Field Emission SEM, Denton Desk II Sputter and Turbo-sputter Coaters.Light and electron microscopic facilities, complete with ancillary support equipment, are located in close proximity to each other within suite of rooms housed in medical school.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core for protein expression and purification as well as all equipment needed for determination of three dimensional structures of biological macromolecules via X-ray crystallography. Houses Rigaku/MSC microMax 007HF generator for X-ray diffraction data collection, equipped with Varimax optics, X-stream 2000 cryosystems and two RaxisIV++ detectors.Also available is stereomicroscope, Nikon SMZ18, for crystal tray observations and crystal mounting., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Facility provides mass spectrometry analysis of proteins. Provides access to mass spectrometry based proteomics technologies and services including Protein Identification, Molecular Weight Determination, Quantitative Protein Analysis, Post-translational Modification Analysis, LC or LC-MS Analysis, Equipment Usage, Additional Data Analysis:Bioinformatics, statistics, pathway analysis and Assistance preparing materials for manuscripts or grants.Consultations for custom assays for other MS Services are also available.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core provides protein and small molecule structural and functional analysis, and quantitation using technologies and software applications. Services in Nano-liquid chromatography,Protein identification and quantitation using SWATH,Protein post translational modification identification,Lipid profiling and identification (MS/MSALL),Targeted multiple reaction monitoring (MRM) for lipids.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core to produce genetically modified mice, rats, and stem cells for the UMMS Scientific Community.Composed of two facilities: Animal Modeling Facility and Gene Targeting and Stem Cell Facility.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core provides consultation services to assist researchers in designing imaging studies, limited labeling services and data acquisition and analysis.Core offers following services:Single Photon Computerized Tomography (SPECT),Positron Emission Computerized Tomography (PET), X-Ray Computerized Tomography (CT),NIR Optical Imaging of small animals.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Facility houses complete collections of human and mouse lentiviral short hairpin RNA (shRNA) libraries from Open Biosystems/GE Dharmacon, Mammalian Gene Collection (MGC) cDNA Library, and human and mouse CRISPR/Cas9 GeCKO v2 libraries from Addgene.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Histology lab that provides histology services in support of investigators at UMass Medical School, including routine histological preparations,special stains,immunohistochemistry,frozen sections.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Facility provides labs with media necessary for Drosophila research. Includes Low Yeast Brown Food, High Yeast Brown Food, and Yellow Food media available in narrow vials, wide vials, and bottles.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core includes three shops: Custom Machine, Harvard Medical School SEAS Scientific Instrument and WPI Manufacturing Labs. Service include consultation, design, manufacturing, modifications, and instrument repairs.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

ELISA for the detection of phosphorylated neurofilament H (pNF-H) in plasma, serum, cerebrospinal fluid, tissue extracts and other fluids. Elevate levels of pNF-H in blood and CSF indicate axonal injury and/or degeneration and are related to the onset and progression of a variety of serious diseases including amyotrophic lateral sclerosis, multiple sclerosis, traumatic brain injury and spinal cord injury.

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• SciCrunch
• 7 years ago - submitted by Gerry Shaw

ELISA for the detection of phosphorylated neurofilament H (pNF-H) in plasma, serum, cerebrospinal fluid, tissue extracts and other fluids. Elevate levels of pNF-H in blood and CSF indicate axonal injury and/or degeneration and are related to the onset and progression of a variety of serious diseases including amyotrophic lateral sclerosis, multiple sclerosis, traumatic brain injury and spinal cord injury.

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• SciCrunch
• 7 years ago - submitted by Gerry Shaw

Facility offers high throughput sequencing and library building services for UMass campuses and outside customers. Operates several types of Illumina next gen sequencers, and is closely integrated with PacBio Core Enterprise and Molecular Biology Core Labs.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core provides instrumentation for determination of crystal structures using X-ray diffraction techniques.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core offers light microscopy platforms providing guidance to researchers with their projects from sample preparation to data analysis, expertise in cellular imaging including live cell imaging, FRAP, FLIM, FRET, FCS, image correlation spectroscopy, TIRF, spectral imaging, high content screening, multi-photon imaging, laser capture micro-dissection, cellular image analysis, and custom image analysis, consultations, image processing, image analysis and preparation of data for publication.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core for full DNA and RNA analysis services. Canada's largest integrated provider of sequencing, genotyping and biochips services. Offers scientific community around the world genomic services in support of research in human health, agrifood, forestry and sustainable development.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth