Curator Dashboard

Core includes three shops: Custom Machine, Harvard Medical School SEAS Scientific Instrument and WPI Manufacturing Labs. Service include consultation, design, manufacturing, modifications, and instrument repairs.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

ELISA for the detection of phosphorylated neurofilament H (pNF-H) in plasma, serum, cerebrospinal fluid, tissue extracts and other fluids. Elevate levels of pNF-H in blood and CSF indicate axonal injury and/or degeneration and are related to the onset and progression of a variety of serious diseases including amyotrophic lateral sclerosis, multiple sclerosis, traumatic brain injury and spinal cord injury.

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• SciCrunch
• 7 years ago - submitted by Gerry Shaw

ELISA for the detection of phosphorylated neurofilament H (pNF-H) in plasma, serum, cerebrospinal fluid, tissue extracts and other fluids. Elevate levels of pNF-H in blood and CSF indicate axonal injury and/or degeneration and are related to the onset and progression of a variety of serious diseases including amyotrophic lateral sclerosis, multiple sclerosis, traumatic brain injury and spinal cord injury.

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• SciCrunch
• 7 years ago - submitted by Gerry Shaw

Facility offers high throughput sequencing and library building services for UMass campuses and outside customers. Operates several types of Illumina next gen sequencers, and is closely integrated with PacBio Core Enterprise and Molecular Biology Core Labs.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core provides instrumentation for determination of crystal structures using X-ray diffraction techniques.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core offers light microscopy platforms providing guidance to researchers with their projects from sample preparation to data analysis, expertise in cellular imaging including live cell imaging, FRAP, FLIM, FRET, FCS, image correlation spectroscopy, TIRF, spectral imaging, high content screening, multi-photon imaging, laser capture micro-dissection, cellular image analysis, and custom image analysis, consultations, image processing, image analysis and preparation of data for publication.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core for full DNA and RNA analysis services. Canada's largest integrated provider of sequencing, genotyping and biochips services. Offers scientific community around the world genomic services in support of research in human health, agrifood, forestry and sustainable development.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Facility provides flow cytometric analysis and cell sorting services to all UConn researchers as well as researchers at neighboring institutions. Located on 6th floor of E building in room E6014, consists of lab space, complete with fume hood, centrifuge, and sink space and has instruments available for cellular analysis and cell sorters.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core to evaluate, select, and implement computational solutions for analysis of biological data.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Resource offers range of mass spectrometry instrumentation, expertise in analysis of RNA, RNA modifications, and proteins involved in RNA metabolism/regulation, supports projects involving analysis of biomolecules, metabolites, and small synthetic molecules, provides consulting on experimental design, sample preparation and data interpretation, whole project development and grant writing contributions.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core sassist users with all their microscopic imaging needs, from the conception of an idea, to final image analysis and presentation.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core for researchers who want to apply advanced molecular genetic techniques in rodent models of physiology and disease. Generates novel mutant mouse strains by using gene targeting in embryonic stem cells (ESCs) and by developing novel methods of modifying rodent genomes and assaying genetically modified cells in vivo.Offers sperm and embryo cryopreservation and storage technologies for strain preservation and recovery.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

CBCB Bioinformatics Core builds upon the infrastructure of the Delaware Biotechnology Institute (DBI) and the Protein Information Resource (PIR).planning your research or analyzing your current data.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core supports DNA Sequencing of PCR, Plasmid, BAC�s and Fosmid templates, Fragment Analysis of Microsatellites, AFLP�s, t-RFLP�s, SHAPE Experiments and Human Cell Line Authentication.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core offers researchers multi laser and multi color flow cytometry sorters and analyzers, including spectral and imaging flow cytometers.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

ABCF can provide MAbs from established hybridomas for RESEARCH PURPOSES ONLY, can assist in generating MAbs, offers a weekly mycoplasmal contamination screening service for tissue culture samples, distributes cell lines developed at Memorial Sloan Kettering Cancer Center and The Rockefeller University

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

MTGTF is to support the investigators in using genetically modified mouse models in Brown University, affiliated hospitals and academic institutions in Rhode Island and other states. The MTGTF provides services of molecular design and generation of transgenic and knock-out mouse models as well as general advice on the use and management of such models. The cutting-edge technologies of the CRISPR/Cas9 system are well established in the MTGTF to accomplish vast majority of the projects in a way of cost friendly, fast, and high quality. The conventional ES cell gene-targeting system is employed to serve as an alternative or to fill the limitations of the CRISPR/Cas9 system. Routine services include genotype analysis, sperm or embryo cryopreservation and storage, rederivation, in vitro fertilization (IVF). Other services, such as mouse vasectomy, embryo transfer, colony scale-up, intracytoplasmic sperm injection (ICSI) are also available. New services requiring MTGTF resources can be created through a request.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core provides services to its users with expertise in biostatistics, microarray data analysis, proteome informatics, next generation sequencing data analysis, functional analysis, database development and information technology, including data storage infrastructure and high performance computing. Working closely with VGN Proteomics Facility, offers investigators experimental design consultations, comprehensive data analysis, data management and publishing, and manuscript and grant support. Core personnel also engage in teaching and training activities for data analysis and compute resources necessary for VGN network investigators. Our goal is to provide network researchers with bioinformatics expertise.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Advanced Genomic Technologies Cluster provides next-generation sequencing and Sanger sequencing. Next-generation sequencing services are provided using Illumina MiSeq and NextSeq sequencers. Services are available for amplicon re-sequencing, viral or microbial whole genome sequencing and 16S microbiome sequencing. Sanger DNA Sequencing can be performed on DNA templates such as PCR products and plasmids using ABI 3730xl and ABI3130xl instruments.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Analytical Imaging Facility (AIF) provides state of the art methods in modern light and electron microscopy imaging to biomedical scientists with all levels of expertise.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth