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Core serves as central molecular biology resource for conception and execution of new projects and provide resources to help offset high costs of developing genetically engineered mice. Ensures better quality control, turn-around time, and cost effectiveness than commercially available services. TACF staff is available for education, assistance and consultation during all stages of project development and production.Serves research staff at West Virginia University, Blanchette Rockefeller Neuroscience Institute and National Institute of Occupational Safety and Health.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core provides proteomics services to researchers from South Dakota and the surrounding region to rapidly analyze and identify protein expression patterns in their experimental systems.Develops experimental design, protocols, data analysis and interpretation.Provides consulting and advice in grant proposal, as well as data preparation to be submitted to proteomics journal according to requirements.Offers training in use of common equipment such as scanner, spot cutter, imaging software, technique and protocol issues, and sample preparation.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Laboratory performs services in proteomics, genomics and metabolomics by FGCZ personnel without need for user to access labs. Services include Proteomics:Protein identification,quantification,characterization,Glycan/glycoprotein analyses, Analysis of Biomolecules, Fractionation; Genomics:DNA sequencing, RNA sequencing; Metabolomics/Biophysics services.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core provides flow cytometry instrumentation and analysis. Instruments include Fortessa, FacsAria and Image Stream.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Genomics and transcriptomics core at the UCD Genome Center provides high throughput sequencing, genotyping, single-cell multi-omics and spatial transcriptomics services, training and consultation. Initial consultations are free. The lab uses liquid handling robots to minimize sample handling variation and to provide fast turnaround times.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Facility is equipped withThermoFisher Orbitrap Fusion Lumos Tribrid mass spectrometer that is interfaced to Dionex Ultimate3000 RSLCnano HPLC system. Facility also maintains 2 separate data stations dedicated for proteomics data processing, database searching, and generation of reports.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Facility provides instrumentation and scientific support for single cell analysis and sorting. Routinely performs analysis of both eukaryotic and prokaryotic cells for expression of intracellular and extracellular proteins, cell cycle, cell proliferation, cytokine production, and cell sorting based on expression of cell surface antigen(s) and/or expression of genetically engineered intercellular fluorescent proteins.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Facility provides integrated synthetic and analytical capabilities for biological materials, including proteins, peptides, and nanoparticles, range of technical expertise and instrumentation. Access is available to all members of MIT community. Priority access is given to KI members, NCI-funded research projects and other contributing user groups in recognition of funding support. In special circumstances, access may be available to non-MIT users.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Provides central location for flow cytometry instrumentation and education. Services include Flow Cytometry,Cell sorting, data analysis, training. Software packages to analyze data include ModFit LT, BD FACSDiva v6, Cell Quest Pro, and FlowJo vX, from facility workstations.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Provides servies in mass spectrometry, proteomics, metabolomics and lipidomics. Services include Thermo Orbitrap Elite and Thermo QExactive HF Orbitrap microcapillary LC-MS/MS:Protein identification, Post-translational modification site mapping,Relative quantification: Label-free, SILAC, TMT, etc.;AB/SCIEX 5500 QTRAP LC-MS/MS:Polar metabolomics profiling,13C/15N metabolic flux analysis;Thermo QExactive Plus/HF Orbitrap LC-MS/MS:Untargeted Lipidomics profiling, Untargeted Metabolomics Profiling.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Provides evolutionary and computational biology investigators with computing and large data storage capacity for use in analyzing and managing large volumes of research data. Core contains advanced mix of high performance computing clusters, servers and data storage components, knowledge and technical skills required to compress years of analysis into days.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Provides advanced instrumentation for researchers interested in investigating biological processes at cellular, sub cellular and molecular level.Instrumentation include Confocal Microscope Systems :Zeiss LSM-510 Meta Confocal Microscope, Olympus FV1000 MPE Basic Multiphoton Microscope;Brightfield/Fluorescence: Nikon Eclipse TE300 (inverted) Fluorescent Microscope, Nikon Eclipse 80i (upright) Fluorescent Microscope, Leica Thunder Imager; TIRF Systems:Olympus TIRF Microscope; Transmission Electron Microscopy:Hitachi 7500 TEM, RCM MTX Ultramicrotomes;Scanning Electron Microscopy:Hitachi 4700 Field Emission SEM, Denton Desk II Sputter and Turbo-sputter Coaters.Light and electron microscopic facilities, complete with ancillary support equipment, are located in close proximity to each other within suite of rooms housed in medical school.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core for protein expression and purification as well as all equipment needed for determination of three dimensional structures of biological macromolecules via X-ray crystallography. Houses Rigaku/MSC microMax 007HF generator for X-ray diffraction data collection, equipped with Varimax optics, X-stream 2000 cryosystems and two RaxisIV++ detectors.Also available is stereomicroscope, Nikon SMZ18, for crystal tray observations and crystal mounting., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Facility provides mass spectrometry analysis of proteins. Provides access to mass spectrometry based proteomics technologies and services including Protein Identification, Molecular Weight Determination, Quantitative Protein Analysis, Post-translational Modification Analysis, LC or LC-MS Analysis, Equipment Usage, Additional Data Analysis:Bioinformatics, statistics, pathway analysis and Assistance preparing materials for manuscripts or grants.Consultations for custom assays for other MS Services are also available.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core provides protein and small molecule structural and functional analysis, and quantitation using technologies and software applications. Services in Nano-liquid chromatography,Protein identification and quantitation using SWATH,Protein post translational modification identification,Lipid profiling and identification (MS/MSALL),Targeted multiple reaction monitoring (MRM) for lipids.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core to produce genetically modified mice, rats, and stem cells for the UMMS Scientific Community.Composed of two facilities: Animal Modeling Facility and Gene Targeting and Stem Cell Facility.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core provides consultation services to assist researchers in designing imaging studies, limited labeling services and data acquisition and analysis.Core offers following services:Single Photon Computerized Tomography (SPECT),Positron Emission Computerized Tomography (PET), X-Ray Computerized Tomography (CT),NIR Optical Imaging of small animals.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Facility houses complete collections of human and mouse lentiviral short hairpin RNA (shRNA) libraries from Open Biosystems/GE Dharmacon, Mammalian Gene Collection (MGC) cDNA Library, and human and mouse CRISPR/Cas9 GeCKO v2 libraries from Addgene.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Histology lab that provides histology services in support of investigators at UMass Medical School, including routine histological preparations,special stains,immunohistochemistry,frozen sections.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Facility provides labs with media necessary for Drosophila research. Includes Low Yeast Brown Food, High Yeast Brown Food, and Yellow Food media available in narrow vials, wide vials, and bottles.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth