Curator Dashboard

Importazole is an inhibitor of importin-β transport receptors. During interphase, the transport receptor importin-β carries cargoes into the nucleus, where RanGTP releases them. Importazole somehow disrupts the importin/RAN interaction. Importazole is selective among other transporters. Compounds are impo

• Resource
• RRID-Legacy
• 7 years ago - submitted by Liliana Pineros Leyton

Proteinase K from Tritirachium album Proteinase K is a stable and highly reactive serine protease. Evidence from crystal and molecular structure studies indicates the enzyme belongs to the subtilisin family with an active-site catalytic triad (Asp39-His69-Ser224). It is stable in a broad range of environments: pH, buffer salts, detergents (SDS), and temperature. In the presence of 0.1-0.5% SDS, proteinase K retains activity and will digest a variety of proteins and nucleases in DNA preparations without compromising the integrity of the isolated DNA.

• Resource
• RRID-Legacy
• 7 years ago - submitted by Liliana Pineros Leyton

Cell permeable fungal toxin that disrupts contractile microfilaments by inhibiting actin polymerization. This, in turn, induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport. One of a group of fungal metabolites that interfere with a wide variety of cellular movements. Useful tool for characterizing some of the polymerization properties of actin, and in studies on cytokinesis. Probe for the two hexose-transport systems in rat L6 myoblasts. PubChem Substance ID 24892890

• Resource
• RRID-Legacy
• 7 years ago - submitted by Liliana Pineros Leyton

Pepstatin A is an inhibitor of acid proteases (aspartyl peptidases). It forms a 1:1 complex with proteases such as pepsin, renin, cathepsin D, bovine chymosin, and protease B (Aspergillus niger). The inhibitor is highly selective and does not inhibit thiol proteases, neutral proteases, or serine proteases. Solubilized γ-secretase and retroviral protease are also inhibited by Pepstatin A. It has been used to characterize proteases from several sources. PubChem Substance ID 24898620

• Resource
• RRID-Legacy
• 7 years ago - submitted by Liliana Pineros Leyton

Inhibits the lysosomal proteinase cathepsin B, and the soluble Ca2+-activated proteinase. Many young plant tissues express a chomostatin-sensitive serine protease. Chymostatin is a strong inhibitor of many proteases, including chymotrypsin, papain, chymotrypsin-like serine proteinases, chymases, and lysosomal cysteine proteinases such as cathepsins A,B,C, B, H, and L. It weakly inhibits human leucocyte elastase. It is effective at a final concentration of 100 to 200 μg/ml (10 to 100 μM). Chymostatin is often included in protease inhibitor cocktails used with plant extracts. PubChem Substance ID 329775144

• Resource
• RRID-Legacy
• 7 years ago - submitted by Liliana Pineros Leyton

Induction of ovulation in mares and female fish. Induction and synchronization of ovulation in sows and gilts. Optimization of fertility in cows and heifers (repeat breeders). Treat

• Resource
• RRID-Legacy
• 7 years ago - submitted by Liliana Pineros Leyton

The GenElute Mammalian Genomic DNA Purification Kit provides a simple and convenient way to isolate pure, high molecular weight DNA from a variety of mammalian sources. These kits use a silica-based membrane, specially selected for genomic DNA purification, in a convenient spin column format. Isolate pure genomic DNA from cultured cells, tissues (including rodent tails), and fresh whole blood or white blood cells. The kit combines the advantages of silica binding with a microspin format and eliminates the need for expensive resins, alcohol precipitation, and hazardous organic compounds such as phenol and chloroform.

• Resource
• RRID-Legacy
• 7 years ago - submitted by Liliana Pineros Leyton

Porcine brain tubulin (>99% pure, see Cat. # T240) has been modified to contain covalently linked HiLyte Fluor™ 488 (HiLyte Fluor is a trademark of Anaspec Inc, CA) at random surface lysines. An activated ester of HiLyte Fluor™ 488 was used to label the protein. Labeling stoichiometry was determined by spectroscopic measurement of protein and dye concentrations (dye extinction coefficient when protein bound is 76,000M-1cm-1). Final labeling stoichiometry is 1-2 dyes per tubulin heterodimer. HiLyte Fluor™ 488 labeled tubulin can be detected using a filter set of 440-460 nm excitation and 500-520 emission. HiLyte Fluor™ 488 tubulin is in a versatile, stable and easily shipped format. It is ready for micro-injection or in vitro polymerization. Cytoskeleton, Inc. also offers AMCA (Cat. # TL440M), rhodamine (Cat. # TL590M), X-rhodamine (Cat. # TL620M) and HiLyte Fluor™ 647 (Cat. # TL670M) labeled tubulins of the same quality.

• Resource
• RRID-Legacy
• 7 years ago - submitted by Liliana Pineros Leyton

Induction and synchronization of ovulation in cow, heifers, sheep & goat. Superovulation (required for embryo transplantation) in cow. Increase of fertility rate.

• Resource
• RRID-Legacy
• 7 years ago - submitted by Liliana Pineros Leyton

Thermo Scientific Leupeptin Protease Inhibitor reversibly inhibits serine and cysteine proteases. Catalog number: 78435

• Resource
• RRID-Legacy
• 7 years ago - submitted by Liliana Pineros Leyton

PubChem Substance ID 24277964

• Resource
• RRID-Legacy
• 7 years ago - submitted by Liliana Pineros Leyton

Software package as spatial graph based computing engine for ecological big data. Modular open source knowledge engine designed to import, organize, analyse and visualize big spatial ecological datasets using power of graph theory. Handles species occurrences and their taxonomic classification for performing ecological analysis on biodiversity and species distributions. Data are linked with relationships that are stored in graph database, while tabular and geospatial data are stored in relational database management system.

• Resource
• RRID-Legacy
• 7 years ago - submitted by Juan Escamilla Molgora

Discontinued software tool used to analyse images. Documented on March 30, 2020. Cheshire intended for clinical use for teleradiology, telecardiology, in hospital view stations and image review for referring physicians.

• Resource
• RRID-Legacy
• 7 years ago - by Anonymous

legacy version of open field locomotor activity software Fully Integrated System for up to 32 animals; Windows xp/vista/7 compatible Software; Powerful Windows based tools for collecting, storing, ... VersaMax System;This product has been replaced by Fusion Open Field - Locomotor Activity. INSUFFICIENT INFORMATION LETTER sent

• Resource
• RRID-Legacy
• 7 years ago - by Anonymous

Open source project to harness scientific and public health potential of pathogen genome data. Provides continually updated view of publicly available data alongside powerful analytic and visualization tools for use by community. Used to aid epidemiological understanding and improve outbreak response. Open source SARS-CoV-2 genome data and analytic and visualization tools.

• Resource
• RRID-Legacy
• 7 years ago - submitted by Anita Bandrowski

Free online archive and distribution server for complete but unpublished manuscripts in the medical, clinical, and related health sciences. Preprints are preliminary reports of work that have not been certified by peer review. They should not be relied on to guide clinical practice or health related behavior and should not be reported in news media as established information. Research articles, systematic reviews and meta analyses, clinical research design protocols and data articles may be posted.

• Resource
• dkNET
• 7 years ago - submitted by Jeffrey Grethe

Software environment that includes tools and integrations for professional Python and Web development. Integrated Development Environment by JetBrains. Used for development in Python and frameworks like DJango. Can be customized with themes and plugins.

• Resource
• RRID-Legacy
• 7 years ago - by Anonymous

Web resource for immunoglobulins (IG), T cell receptors (TR) and major histocompatibility (MH) and related proteins of immune system (RPI). Comprises LIGM expertized data on immunoglobulins (IG), T cell receptors (TR) and major histocompatibility (MH) and related proteins of immune system.

• Resource
• RRID-Legacy
• 7 years ago - by Anonymous

Web server for structure validation in homology modeling. Used to validate of obtained crude models. Structure analysis and validation server.

• Resource
• RRID-Legacy
• 7 years ago - by Anonymous

Software R Package that provides parameter-free method for optimizing trade-off between resolution of clusters and their replicability across datasets. Dune method takes as input set of clustering results on dataset, and iteratively merges clusters within those clusterings in order to maximize their concordance. Iterative merging of clusters to improve mean ARI

• Resource
• RRID-Legacy
• 7 years ago - submitted by Anita Bandrowski