Curator Dashboard

Software Python package and command-line toolkit for processing and analyzing three-dimensional brain imaging data, particularly cleared-tissue light-sheet fluorescence microscopy datasets. Supports image preprocessing, atlas registration, cell segmentation and quantification, voxel-wise statistical analysis, cluster characterization, and region-wise analysis of fluorescence intensity and cell density. UNRAVEL also facilitates integration of brain-wide imaging results with Allen Institute resources, including the Allen Brain Cell Atlas and neuronal connectivity datasets, to investigate the cellular and circuit-level organization of observed brain activity patterns.

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• 2 weeks ago - submitted by Daniel Rijsketic

Core Facility provides comprehensive bioinformatics support for cancer research, including experimental design, data processing, statistical analysis, and biological interpretation of high-throughput genomic data. Offers expertise in bulk and single-cell RNA sequencing, DNA sequencing and variant analysis, spatial transcriptomics, epigenomics, image analysis, and integrative multi-omics analysis. BISR also develops and maintains computational workflows, provides AI and machine learning expertise, and supports the computational infrastructure needed for large-scale genomic analyses, image processing, and AI-driven research.

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• SciCrunch
• 2 weeks ago - submitted by Edyta Vieth

Core ofers Cryo-EM services focused mostly on Single Particle Analysis. Our microscopes include a Titan Krios with Gatan K3 detector.

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• SciCrunch
• 2 weeks ago - submitted by Edyta Vieth

Bruker Avance Neo 600 MHz NMR Spectrometer paired with a QCI-P CryoProbe is an advanced 14.1-Tesla liquid-state nuclear magnetic resonance (NMR) system designed for high-sensitivity structural biology, metabolomics, and multi-nuclear research. This 600 MHz NMR spectrometer features a Bruker Neo console for optimized spectrometer operation with a 5-mm quadruple-nuclei QCI-P (1H, 13C, 15N, and 31P) cryoprobe. This probe boasts 400% increases in sensitivity relative to a room temperature probe, and is an ideal tool for analyzing biomolecular systems, such as peptides, proteins, and DNA/RNA, as well as organometallic samples in solution. With the assistance of the Bruker BioTop package and a sample changer (SampleCase), the instrument has been utilized to automatically collect various advanced 1D, 2D, and 3D NMR data sets for biological systems on a 24/7 basis. A conventional 5-mm triple-resonance probe (TXI) is used as a backup for the QCI-P CryoProbe.

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• 2 weeks ago - submitted by Caitlin Quinn

Software Python command-line tool and derived data for shortlist membership audits. Code and derived-data research artifact: specification and cutoff-tie uncertainty in cancer-target shortlists.

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• 2 weeks ago - by Anonymous

Web-based data analysis software for bioassays, including ELISA standard curve fitting, IC50 and EC50 dose-response analysis, parallel line analysis for relative potency, kinetic assay reduction with group statistics, and ecotoxicological risk and pollution indices.Bioassay Analysis Platform used for automated quality control and nonlinear regression in microplate bioassays.

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• 2 weeks ago - submitted by Marek Helczman

Small animal fluorescence imaging system designed for manual operation to provide a more affordable, lower-throughput option. Entry-level, manually operated system that replaces the original Maestro M1 system. Enables more precise detection and quantitation of molecular probes in live animals and complements the automated high-throughput Maestro 2 imaging system, by providing comparable imaging performance in a design intended for lower-throughput manual operation.

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• 2 weeks ago - by Anonymous

Software tool for alignment and preprocessing of high-throughput chromatin profiling sequencing data, including ATAC-seq, single-cell ATAC-seq, ChIP-seq, and Hi-C. Supports genomic read mapping, adapter trimming, duplicate removal, barcode correction, and quality control analysis, enabling efficient processing of bulk and single-cell sequencing datasets. Used for aligning and preprocessing high throughput chromatin profiles.

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• 2 weeks ago - by Anonymous

Core facility which accompanies researchers in all their projects steps: study design, sample size, choice of methods, data analysis, presentation and interpretation of results, redaction and revision of protocols, grant applications and manuscripts.

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• 2 weeks ago - submitted by Anne-Sophie Julien

Software tool as Model Context Protocol server with lab math tools: reconstitution concentration, unit conversion, C1V1 dilution, molarity, percent w/v, serial dilution. Browser extension and MCP server (npm: reconstitution-calculator-mcp)

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• 2 weeks ago - submitted by Peptara Labs

FISH Assay to determine MET GCN and MET/CEN7 ratio in FFPE samples

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• 2 weeks ago - by Anonymous

Wireless, pressure based analgesimeter to measure mechanical pain sensitivity thresholds in small animals, including mice and rats. Applies progressive force to assess mechanical allodynia and hyperalgesia and is used in studies of osteoarthritis, neuropathy, inflammation, postoperative pain, and analgesic drug screening. Electronic pressure based analgesimeter designed for preclinical research on small rodents like mice and rats.

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• 2 weeks ago - by Anonymous

Automated slide staining instrument used in pathology and oncology laboratories to automate the preparation and staining of tissue and cell samples for cancer diagnostics and medical research.Baking, deparaffinization, cell conditioning and staining, including IHC, ISH, SISH, immunofluorescence, multiparameter IHC staining (dual, triple), counter stain and titration. Approximately 40 slides in 8 hours (standard IHC samples) Approximately 20 slides in 8 hours (standard ISH samples).

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• 2 weeks ago - by Anonymous

This is a test

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• 2 weeks ago - submitted by Ko-Wei Lin

Independent, freely accessible knowledgebase of vitamin D research. Provides searchable publication records, links to original scientific sources, study summaries, and educational guides. Human, animal, and laboratory research are distinguished. AI-assisted summaries are identified as preliminary and do not constitute independent medical review or medical advice.

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• 2 weeks ago - by Anonymous

High performance laser scanning confocal microscope used for advanced, gentle, and high-speed super resolution fluorescence imaging of biological samples, from single live cells to thick 3D tissue sections. Super resolution imaging, high light sensitivity, and fast live cell scanning is achieved by using ZEISS Airyscan 2 which is specialized 32-element area detector module used on laser scanning confocal microscopes.

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• 2 weeks ago - by Anonymous

Core houses its own research-dedicated Siemens 3T Cima.X Magnetic Resonance Imaging (MRI) scanner. The scanner includes multiple head and body coils for different applications and optional capabilities for concurrent 256-channel high-density electroencephalography (EEG), eye tracking, BioPac physiological monitoring, and real-time motion monitoring. It is also equipped with all standard sequences for functional and structural neuroimaging and for sequences enabling multiband imaging for faster and higher-resolution fMRI data acquisition. Facility maintains a Siemens Master Research Agreement, making the facility part of a network of research imaging centers that have access to research-grade MRI protocols and sequences. Offers expertise of MRI technologists. Neuroradiologists from the University of Nebraska Medical Center review scans from all research subjects for incidental findings. A highly realistic mock scanner is also available in an adjoining room for familiarizing research subjects with the MRI environment and cognitive testing protocols.

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• 2 weeks ago - by Anonymous

Core provides Cryo-EM services focused mostly on Single Particle Analysis. Housed microscopes include a Titan Krios with Gatan K3 detector.

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• 2 weeks ago - submitted by Laura Koepping

Core facility provides in vitro and in vivo metabolic phenotyping services. Offers expertise in experimental design and data analysis.

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• 2 weeks ago - submitted by Victoria DeMambro

Core provides collaboration, consultation, and training on Data Science with a focus on Biomedical Data, including Genomics, Transcriptomics, and Spatial analysis. Offers expertise in workflow management/development, cloud computing, and data science skills.

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• 2 weeks ago - submitted by Joel Graber