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Core provides on-site repair and maintenance services for autoclaves and laboratory washers.Core is also responsible, in collaboration with Environment, Health and Safety, for temperature probe calibrations of autoclaves located in FoMD enhanced biocontainment facilities.
Provides access to flow cytometry and cell sorting technologies and instruments. If your research requires cytometric analysis, instruments acquire optical measurements using different lasers to detect fluorophores with high level of precision.
Core provides computational analysis for high throughput genomic data, including but not limited to, next generation sequencing data. Our mission is to accelerate scientific discoveries by guiding experimental design, performing robust data quality assessment, and carrying out comprehensive computational analyses. Registration to iLab required.
Core assists in producing quality histological slides.Provides equipment and expertise to produce sections from frozen, paraffin-embedded, and resin-embedded tissues,routine hematoxylin and eosin stained slides, immunohistochemical and special stains.Registration to iLab required.
Core assists researchers in isolating and quantifying lipids and lipid related molecules in experimental samples.Core uses high performance liquid chromatography, gas chromatography, and fast protein liquid chromatography for both qualitative and quantitative analysis of lipids and lipoproteins, as well as other compounds by special request.Not-for-profit, pay-per-use facility, with graduated fee schedule based on client affiliation.
Core provides mouse transgenic and cryopreservation services including Sperm cryopreservation, Mouse in vitro fertilization, Mouse Rederivation, Transgenic Mouse Generation,DNA microinjection,CRISPR/Cas9-Mediated Genetically Engineered Mouse Production. Core equipment includes Hamilton Thorne Computer-Aided Sperm Analysis System,Sutter Xenoworks Micromanipulator,Sutter Xenoworks Digital Microinjector,Nikon TE2000 inverted microscope,MINC benchtop incubator,Leica M165 dissecting microscope.
Designed to provide supportive environment for interdisciplinary research and education with opportunities for students and faculty members alike with focus on biomolecules study with emphasis on proteins and protein interactions. Provides instrumentation and facilities for characterization of biomolecules and their role in variety of biomedical and environmental processes. Partnerships between Center and Idaho-BRIN/INBRE, UI, ISU, Boise VA Medical Center, College of Idaho, and Northwest Nazarene University. BRC provides seminars, training workshops, and other networking opportunities.
Provides scanning electron microscopy services including biological tissues and cells,and particulate characterization.
Core provides nanobodies production for research as well as protein production, purification, and macromolecular characterization. Offers training on all instruments and equipment, as well as higher level of assistance when projects warrant.
Provides investigators with genetically manipulated mice through transgenic technology or embryonic stem cell manipulation. Provides fully operational construction and gene targeting service. Offers annual course in Mouse Handling and Breeding. Provides transgenic plasmid and BAC, CRISPR and TARGATT injections, ES Cell targeting, screening, culture and blastocyst injections, rederivation, breeding and mouse services and consultation on project development.
Core provides flow cytometry services to UNCCH research community as well as to others in Research Triangle Park area.Provides help with experimental design, sample acquisition, data analysis, and sorting, training to run analyzers independently at reduced cost, guidance about rigor and reproducibility in all aspects of experimental design, data acquisition, analysis and reporting.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 18,2022. Provides services in molecular biology with DNA sequencing, capillary and high throughput services, single cell sequencing services using 10X genomics and Drop-Seq platforms, Luminex, oligonucleotide synthesis (IDT), HPLC analysis and purification, real time PCR and others.
Core helps researchers identify and interpret patterns in RNA and DNA by placing sequencing data into biologically meaningful context. Services include experimental design, developing reproducible workflows, analyzing next-generation sequencing data, and supporting manuscript development/publication.
Provides custom made microbiological media for bacteria,yeast,C.elegans,Chlamydamonas research in liquid and agar forms. Common lab buffers and solutions are also available.
Core provides professional scientific expertise in light microscopy. Offers access to hardware and software as well as expert guidance at any step of imaging project, from experimental design to image analysis.Comprises eight microscope systems including two laser scanning confocal microscopes including one Olympus inverted confocal microscope system (FV1000) and one Zeiss inverted confocal microscope system (LSM-980) equipped with Airy scan 2 for super resolution and 2-photon technology for in-vivo deep imaging with temperature controlled chamber. One spinning disk confocal including Nikon inverted spinning disk microscope system with incubation chamber (Eclipse Ti with Yokogawa disk CSU-W1), two Zeiss widefield microscopes for brightfield and epifluorescence illumination (Zeiss Apotome and Zeiss Colibri), three macroscopes systems to observe large samples or complete model organisms in brightfield and epifluorescence including one Olympus stereomicroscope system (MVX10) and two Zeiss stereomicroscope systems (SteREO Discovery V12), fully automated and one AxioZoom V16 , fully automated with ApoTome attachment.
Offers services in customized end point assays using human WB/PBMCs for clinical trials, ELISPOT, multiplex cytokine analysis, cell energy analysis, blood processing and cryopreservation,up to 20 color flow cytometry phenotyping and up to 11color FACS cell subset sorting. Provides consultation, data analysis, and Flow Cytometry training course.
Software tool to generate standard organizational structure for Next Generation Sequencing data analysis. Includes directory structure for project, several Jupyter notebooks for data management and CWL workflows for pipeline execution.
THIS RESOURCE IS NO LONGER IN SERVICE.Documented on January 14, 2023. Repository of specimen in European Union associated with DISScO project.
Repository for biodiversity data products managed by Department of Planning, Industry and Environment, New South Wales, Australia. It stores species sightings, systematic surveys, threatened biodiversity records and species names.
Automated image analysis software package for accurately visualizing and quantifying biomarkers in tissue sections. Designed to meet workflow and throughput needs of research pathology, oncology, immunology. Used for tissue analysis.