We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Genetic Analyzer with two FlowChips, embedded quality controls, user workflows, and project scalability. It can be used for whole exome sequencing or targeted resequencing with up to 96 barcodes.
PCR bechtop thermal cycler measuring at only 36 x 21 x 22 cm and several machines can be stored and operated side-by-side.
Reagent dispenser that handles a wide selection of plates and volume range and provides fast dispensing and high-throughput operation. It dispenses over a 0.5 to 2500�L range, ensuring reproducible assay data and accommodates microplates from 6 to 1536 wells and plate heights of 5 to 50mm.
Modular stereomicroscope with 6.3:1 zoom with 7-position ratchet stop enables repetitive inspection and measurements at a specific zoom position.
Genetic analyzer, referred to as Chromium Controller for combining large partition numbers with a diverse barcode library to generate >100,000 barcode-containing partitions. Chromium Controller runs low- and standard-throughput assays. It does not run high-throughput assays.Chromium Controller uses advanced microfluidics to perform single cell partitioning and barcoding in a matter of minutes. Powered by Next GEM technology, the Chromium Controller enables integrated analysis of single cells at massive scale.
Software tool enabling interactive signal processing and visualisation of mass spectrometry imaging datasets. Extends open source Medical Imaging and Interaction Toolkit. Designed to enable multi modal 2D registration and 3D MSI reconstruction.
Software tool to simplify and to speed calling and genotyping structural variants for short reads. Improves specificity by removing many spurious alignment signals that are indicative of low level noise and often contribute to spurious calls.
Software tool as MSS-MLE calculator for Luria–Delbrück fluctuation analysis.
Software R package consisting of suite of tools for doublet detection, modality integration, clustering, differential RNA and protein expression analysis, antibody-derived tag evaluation, ligand-receptor interaction analysis and interactive web-based visualization of CITE-seq data.
Source code for alpha-helix simulation framework written in Matlab. Specifically tested on Talin-1 Rod Domain.
Software tool to separate junction reads based on their linear or circular origin. Only non ambiguous junction reads are used to compare relative linear and circular transcript abundance.
Software R package as efficient implementations for all popular synergy scoring models for drug combinations, including HSA, Loewe, Bliss and ZIP and visualization of synergy scores as either two dimensional or three dimensional interaction surface over dose matrix. Used to calculate and visualize synergy scores for drug combinations.
Software R package provides infrastructure for manipulation, processing and visualisation of mass spectrometry and proteomics data, ranging from raw to quantitative and annotated data. Used for isobaric tagged mass spectrometry data visualization, processing and quantitation.
Software R package provides functions for pathway analysis based on REACTOME pathway database. It implements enrichment analysis, gene set enrichment analysis and several functions for visualization.
Software R package implements functions for helping in process of disease patterns analysis by means of principal components. These include component visualization, interpretation and stability analysis.
Core serves research needs of entire campus community as well as outside research entities. Facility maintains a variety of NMR spectrometers at variety of magnetic fields to support research needs.
Provides resources for crystallization and structure determination of biological macromolecules and complexes. Supports research in the Department of Biochemistry. We are happy to extend our help to researchers from the broader CU community and to researchers outside the university, if time and availability allow us too.
Provides instruments including BD Accuri C6 Cytometer with Automated, multisampler/Flow Cytometer,BDFACSCelesta Flow Cytometer Analyzer,BD FACSAria Fusion Cell Sorter.
Core instruments include Agilent Bioanalyzer 2100 system provides sizing, quantitation and quality control of DNA, RNA and proteins, Illumina MiSeq sequencer, able to sequence prepared Illumina DNA or RNA libraries at low- to mid- output (0.75 to 13 Gbp per run), Illumina NextSeq sequencer capable of sequencing Illumina DNA or RNA libraries, QuantStudio 6 Real-Time PCR uses fluorescence detection method for quantitative and qualitative analysis of nucleic acid sequences including gene expression, regulation and variation, Qubit Fluorimeter 3.0 capable of measuring DNA or RNA concentrations with high accuracy.
Facility provides specialized services for assessment of material properties, chemistry and structure across multiple length scales with emphasis on assessment of biological tissues, biomaterials, and biologically inspired systems.