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Microplate Reader delivers single mode reader performance and can be equipped to read volumes as low as 2uL in one multimode reader package. The dual monochromator optics allow the widest range of applications to be utilized for bioresearch and drug discovery applications, all without the need to change filters. For fluorescence intensity, time resolved fluorescence, and fluorescence polarization assays, the SpectraMax M5 Microplate Reader optical design provides the highest level of flexibility. Users can select from top or bottom read modes for improved sensitivity for solution and cell-based assays. Assays can be better optimized by scanning across a range of wavelengths in increments as small as 1 nm. Up to 4 wavelength pairs can be read in one protocol for endpoint and kinetic measurements, allowing for fast setup of FRET and TR-FRET assays. For luminescence, the SpectraMax M5 Microplate Reader utilizes a dedicated luminescence photomultiplier tube (PMT), providing the user the maximum signal and lowest background possible for glow luminescence reporter gene assays. The SpectraMax M5 utilizes a single monochromator design for UV/VIS Absorbance, allowing the user to maximize sensitivity and tunability, and also uses patented PathCheck Pathlength Measurement Technology: the only temperature independent pathlength correction for microplates. The M5 can read volumes down to 2uL with the uMax Low Volume Plate.

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• SciCrunch
• 6 years ago - submitted by Edyta Vieth

Typhoon 8600 Variable Mode Imager unites storage phosphor autoradiography technology with fourcolour fluorescent labelling techniques for maximum data quality in a single, high-throughput system.

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• SciCrunch
• 6 years ago - submitted by Edyta Vieth

Microplate reader built on Gemini platform delivering high quality top and bottom reading for both solution and cell based assays. The Gemini EM can sample a variety of formats, from 6- to 384-well microplates, in different modes, such as endpoint, spectral scan, kinetic, and well scan. This reader's dual monochromators for excitation and emission cover the wavelength selection from 250 to 850 nm. Utilize both top and bottom fluorescence reading for the best optical sensitivity, and read up to four wavelength pairs in endpoint and kinetic measurements. The Gemini EM offers superb accuracy and reproducibility of results, possible with AutoPMT electronics, calibration for comparing RFUs between samples, consistent temperature regulation, programmable Automix, gentle movement, seamless automation, and comprehensive reader validation. Applications for the Gemini EM include enzyme assays, protein quantitation, microbial growth, ELISAs and immunoassays, transporter assays, nucleic acid quantitation, phosphotases/kinases, reporter gene assays, and cell viability, proliferation, and cytotoxicity.

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• SciCrunch
• 6 years ago - submitted by Edyta Vieth

Multidetection microplate readers with dualmonochromators, dual-mode cuvette ports, and top- and bottom-reading capability. Detection modalities include absorbance (UV-Vis Abs) and fluorescence intensity (FI). Endpoint, kinetic, spectrum and area-well scanning read types and the PathCheck Sensor allow homogeneous and heterogeneous microplate assays to be performed in one flexible system. SpectraMax M2 readers provide for easy conversion and optimization of very-low-throughput to medium-high-throughput assays, faster, more precise results and reagent savings. In addition, combined absorbance and fluorescence intensity assays can be run by issuing a single read command.

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• SciCrunch
• 6 years ago - submitted by Edyta Vieth

SPECTRAmax GEMINI XS Dual-Scanning Microplate Spectrofluorometer can perform a variety of fluorescent applications as well as some time-resolved fluorescent and luminescent assays. The extreme flexibility and high sensitivity of the SPECTRAmax GEMINI XS make it appropriate for applications within the fields of biochemistry, cell biology, immunology, molecular biology, and microbiology. The SPECTRAmax GEMINI XS uses two holographic diffraction grating monochromators which allow for individual optimization of wavelengths for both excitation and emission. The dual-scanning capability can also be used to determine excitation and emission settings for new fluorescent probes. Mirrored optics focus the light into the sample volume and cutoff filters are used to reduce stray light and minimize background interference. The light source is a highpowered Xenon flashlamp; additional flexibility is provided by allowing a variable number of lamp flashes per read. Microplates having 6, 12, 24, 48, 96, and 384 wells can be used in the SPECTRAmax GEMINI XS. Fluorescent detection is achieved from the top, through the entire depth of sample in the microplate well. Detection of species collected on membrane plates is also possible. Two plate carrier adapters are provided with the instrument. The blue adapter is required for optimum performance with standard 96- and 384-well format microplates. The red adapter has been optimized for use with Cliniplate 384 microplates.

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• SciCrunch
• 6 years ago - submitted by Edyta Vieth

Designed for dissociation of rodent neural tissue older than P7 for subsequent isolation of neurons, astrocytes, or oligodendrocytes.

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• SciCrunch
• 6 years ago - submitted by Edyta Vieth

ImageXpress Micro Confocal system is a high-content solution that can switch between widefield and confocal imaging of fixed and live cells. It can capture high quality images of whole organisms, thick tissues, 2D and 3D models, and cellular or intracellular events. The spinning disc confocal and sCMOS camera enable imaging of fast and rare events like cardiac cell beating and stem cell differentiation. With MetaXpress software and flexible options like water immersion objectives to choose from, the system enables many confocal imaging applications from 3D assay development to screening.

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• SciCrunch
• 6 years ago - submitted by Edyta Vieth

Developed for generation of single cell suspensions from neural tissues. Neural Tissue Dissociation Kit and Postnatal Neurons has been optimized for needs of sensitive postnatal neurons during dissociation.

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• SciCrunch
• 6 years ago - submitted by Edyta Vieth

Thermocycler that operates with 96 well and 60 well microplates. Has temperature configurations from 0 C to 105 C and pressure and height adjustment via thumbwheel. Comes with 14 pre-programmed protocols.

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• SciCrunch
• 6 years ago - submitted by Edyta Vieth

Developed for generation of single cell suspensions from mouse and rat adipose tissue. It has been optimized for high yield of non adipocyte lineages, including adipose tissue derived stem and progenitor cells, immune cells, endothelial cells and stromal cells while preserving cell surface epitopes.

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• SciCrunch
• 6 years ago - submitted by Edyta Vieth

Developed for generation of single cell suspensions from cultured neurospheres. Dissociated cells are immediately ready for further in vitro or in vivo applications, such as cell culture and expansion, flow cytometry, fluorescence microscopy, and molecular applications, or for cell separations using MACS® Technology.

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• SciCrunch
• 6 years ago - submitted by Edyta Vieth

Offers advanced integrated solutions to streamline cell processing workflows from cell separation through cell culture to formulation of final product. Offers flexible platform for cell processing applications enabling magnetic separation of different cell types and customized cell processing protocols.

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• SciCrunch
• 6 years ago - submitted by Edyta Vieth

Developed for generation of single cell suspensions from mouse liver. It has been optimized for high yield of non parenchymal mouse liver cells, including liver sinusoidal endothelial cells, LSECs, and Kupffer cells, while preserving most cell surface epitopes

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• SciCrunch
• 6 years ago - submitted by Edyta Vieth

Developed for generation of single cell suspensions from mouse spleen. It is optimized for high yield of leukocytes, especially dendritic cells, while preserving all cell surface epitopes.

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• SciCrunch
• 6 years ago - submitted by Edyta Vieth

Developed for generation of single cell suspensions from mouse lung in combination with gentleMACS Dissociators.

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• SciCrunch
• 6 years ago - submitted by Edyta Vieth

Developed for generation of single cell suspensions from tumor tissue generated by implanting mouse tumor material into second mouse. Kit is optimized for high yield of tumor cells and tumor infiltrating lymphocytes.

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• SciCrunch
• 6 years ago - submitted by Edyta Vieth

Developed for generation of single cell suspensions from mouse epidermis, e.g. for subsequent isolation of Langerhans cells using Epidermal Langerhans Cell MicroBead Kit.

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• SciCrunch
• 6 years ago - submitted by Edyta Vieth

Developed for isolation of lamina propria immune cells from small intestine of mouse, using gentleMACS Dissociators.

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• SciCrunch
• 6 years ago - submitted by Edyta Vieth

Developed for generation of single cell suspensions from neonatal mouse and rat heart tissue. Kit is optimized for high yield of cardiomyocytes, while preserving important cell surface epitopes.

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• SciCrunch
• 6 years ago - submitted by Edyta Vieth

Developed for generation of single cell suspensions from murine and rat skeletal muscle tissue. It is optimized for high yield of viable cells, for example satellite cells, while preserving important cell surface epitopes. Mature myotubes will be destroyed.

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• SciCrunch
• 6 years ago - submitted by Edyta Vieth