We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
System provided by University of Delaware. The AVIII 400 MHz NMR spectrometer is equipped with a Bruker BBO Probe and a BBI probe, as well as a Bruker InsightMR reaction monitoring system. This instrument is ideal for analyzing time and air sensitive samples. It is also suitable for monitoring reaction kinetics of chemical reactions and for variable temperature (VT) NMR measurements.Console: Avance III; Field Strength: 400 MHz; Software: InsightMR. The BBO probe is a two-channel (1H and X-nucleus) probe with automatic tuning and match capabilities. The observe channel (X) covers a frequency range from 109Ag to 19F. The sample temperature range of this probe is -150 to +150°C. The BBI probe is a two-channel (1H and X-nucleus) probe with automatic tuning and match capabilities. The observe channel is optimized for 1H and the decoupling channel is tunable to a broadband frequency range.
System provided by University of Delaware. High-sensitivity continuous-wave Electron Paramagnetic Resonance (CW-EPR) spectrometer. It detects and analyzes unpaired electrons in chemical, biological, and physical samples. Offers both X-band and Q-band detection along with a cryogenic variable temperature (VT) control system.
Independent statutory Australian Government agency with more than 35 years of experience working with health and welfare data. Collects, analyzes, and publishes national data and statistics on health and community welfare.
Software command-line pipeline that preprocesses data from metabolic labeling scRNA-seq experiments and quantifies the following four mRNA species: unlabeled unspliced, unlabeled spliced, labeled unspliced and labeled spliced. Can perform statistical estimation of these species through expectation maximization (EM) and Bayesian inference.
Web citation repair tool targets academics, researchers, and students. It helps repair mangled datasets.
Software analysis pipeline for high-resolution spatial mapping and quantification of mRNA expression in nervous system tissue. Used for spatial high-dimensional in situ hybridization (HiPlex RNAScope).
Software Python-based graphical user interface software tool developed by AtlasXomics. Designed for the preprocessing of high-resolution tissue images generated during DBiT-seq spatial multi-omics assays.
Software multi-sample multi-group scRNA-seq analysis R package. Used to perform differential state (cell-type-specific differential expression) analysis on multi-sample, multi-condition single-cell RNA-seq (scRNA-seq) data. Avoids false-positive errors from single-cell-level tests by aggregating counts into "pseudobulk" profiles or using mixed models.
Biotechnology company founded in 2020 as a spin-out from Yale University. It specializes in spatial biology, allowing researchers to map gene regulation, chromatin accessibility, histone modifications, and DNA methylation directly inside intact tissue samples at cellular resolution. Using DBiT-seq technology and FlowGel microfluidic chips, it enables spatial mapping of chromatin accessibility, histone modifications, and DNA methylation at near-cellular resolution (10 × 10 µm). The platform supports fresh-frozen and FFPE tissues, with data visualization and analysis through AtlasXplore and compatible bioinformatics tools.
Web platform to interactively navigate a growing collection of spatial epigenome data. Used for interactive visualization and sharing of high-dimensional spatial epigenome data. Allows to explore gene activity, motif deviation scores, and eRegulon networks across solid tissue sections without complex coding. Can be used to view and analyze data from a variety of sources, including whole-genome sequence data, transcriptome data, and other types of genomic data.
System provided by University of Delaware is used to study the atomic structure of solid materials, insoluble polymers, and semi-solid biological tissues. Operating at 14.1 Tesla, it features an UltraShield magnet for superior stray-field reduction and spatial efficiency. Console: Avance III ; Magnet: Ultrashield; Field Strength: 600 MHz; Software:TopSpin. Equipped with several probes for solid state and HR-MAS applications and is used primarily for the study of polymers and materials by MAS NMR: a 3.2 mm H(F)X probe (15N-31P) for a wide range of organic and inorganic systems, common nuclei include 13C, 15N, 27Al, 29Si, and 19F; a 3.2 mm E-free HCN probe for studies of high-salt 13C, 15N isotopically enriched biomolecules; specialized 3.2mm probes for applications of 2H and 77Se NMR; and a 4mm HX HR-MAS probe for hydrogel and tissue like samples.
System provided by University of Delaware is used to study the atomic-scale structure, dynamics, and chemical environments of solid materials like polymers, ceramics, catalysts, and biological solids. Console: Bruker Avance III; Magnet: Ultrashield; Field Strength: 11.7 Tesla/500 MHz. The AVIII 500 MHz solid state NMR spectrometer is equipped with several probes for NMR studies: 1.3mm HFX probe for fast spinning 1H- and 19F-detected experiments, a 3.2mm EFree HCN probe for studies of high-salt 13C, 15N isotopically enriched biomolecules, a NHMFL 3.2mm Low-E HXY probe for for studies of high-salt systems and multinuclear experiments, a Bruker 4mm HX probe (tuning range 15N to 31P), and a Bruker 4mm low gamma probe (tuning range 109Ag to 13C).
System provided by University of Delaware. High-resolution analytical instrument used to determine molecular structure, study chemical dynamics, and analyze materials. It uses a 9.4 Tesla superconducting magnet to perform multinuclear 1D and 2D experiments on both liquid-state and solid-state samples. Console: Avance Neo. Magnet: 9.4 Tesla / 400 MHz. Software: ICONNMR. Located on the ground floor of the Ammon Pinizzotto Biopharmaceutical Innovation Center on the UD STAR Campus, this Neo 400 MHz is equipped with a 5-mm Bruker iProbe and sample changer (SampleCase) for rapid turn-around NMR service. The iProbe has broadband channel that covers a frequency range from 109Ag to 31P and 19F and an optimized proton channel for 1H detection. This spectrometer is primarily used to support synthetic chemists, biochemists, and material scientists on the STAR campus.
High-resolution system provided by University of Delaware is used to determine the chemical structure, purity, and dynamics of molecules. It combines a 400 MHz superconducting magnet with an advanced digital control console to analyze nuclei like ¹H, ¹³C, and ¹⁹F. Console: Avance Neo; Magnet: Ultrashield Plus; Field Strenght: 400 MHz. This 400 MHz NMR spectrometer features a Neo console, a 5-mm BBFO probe, and a sample changer (SampleCase) to provide NMR service on a 24/7 basis. The broadband channel of the probe covers a frequency range from 109Ag to 31P and 19F. The day-queue is reserved for rapid turn-around analysis and routine experiments such as 1D 1H, 13C, 19F, and 31P spectra. The night-queue is reserved for experiments that require more than one hour of instrument time such as 13C NMR for dilute samples and two-dimensional experiments (COSY, HMQC, HSQC, NOESY).
High-resolution Nuclear Magnetic Resonance (NMR) system provided by University of Delaware is used in chemistry, biology, and pharmacology to analyze molecular structures, dynamic processes, and purity. Console: Bruker Avance Neo; Magnet Field Strength: 14.1 Tesla / 600 MHz; Probe: Bruker CryoProbe Prodigy; Software: Bruker TopSpin. This Bruker Neo 600 MHz Spectrometer with Prodigy cryoprobe has two channels: one for 1H/19F detection, and one broadband channel covering observe frequencies from 109Ag to 31P. Compared with a conventional room temperature probe, the Prodigy probe provides 2 to 3 times better signal-to-noise ratios. A conventional 5-mm BBFO is available as a backup for the Prodigy cryoprobe. The instrument is also equipped with a SampleCase autosampler. The day-queue is reserved for quick turn-around experiments such as 1D 1H, 13C, 19F, and common 2D experiments. The night-queue is reserved for time-consuming 1024+ scan 13C NMR required for low concentration samples, and some special 2D experiments. This spectrometer is largely used to support synthetic chemists, material scientists, and engineering researchers.
Automated benchtop laboratory system used to dissociate solid tissue samples into single-cell or single-nucleus suspensions. Tissue dissociation machine that can process two samples simultaneously.
Benchtop sequencing instrument with reimagined core technology to deliver flexibility and affordability while setting the standard for data quality. Next-Generation Sequencing (NGS) system used to read DNA and RNA sequences quickly, accurately, and at a lower cost than traditional large-scale sequencers.
Genomics core at Scripps Research provides genomic services including Next Generation Sequencing, Custom Library Design and Preparation, Single Cell Genomics, Spatialomics, Custom Microarrays.
Software toolkit for unbiased single-cell transcriptomic data cell type identification. Provides a meta-database of thousands of human and mouse cell identity markers curated from multiple sources, along with methods for cell type prediction based on marker gene overlaps or gene set enrichment.
Software Python research toolbox for reproducible, multiresolution modeling of ocular and extraocular electrical stimulation. It registers electrode designs to voxel-based eye and head anatomy, directly assembles sparse admittance systems, solves voltage and current-density fields, quantifies retinal and off-target exposure, evaluates access impedance and charge density, and maps extracellular potentials onto compartmental neuronal models in NEURON. Researchers can use NeuroAM to compare electrode locations, geometries, return paths, and stimulation parameters before experimental implementation. Multiresolution modeling and parallel field reconstruction reduce memory requirements and computation time for workstation-scale anatomical models.