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Software R package offers a panel of functions for kinase activity inference on an input phosphoproteomics dataset using the Kinase-Substrate Enrichment Analysis (KSEA) method originally described by Casado et al.
Automated platform used in behavioral neuroscience to track and analyze the movements and behaviors of lab animals, such as mice and rats. Standardizes experiments like the Elevated Plus Maze, Open Field, Barnes Maze, and Fear Conditioning. Tracks whole-body movement, distance traveled, freezing/immobility, and zone entries. Connects to external devices like food dispensers, shockers, and lasers to trigger automated responses based on the animal's actions.
Norway's largest medical institution and Scandinavia’s largest hospital, employing over 20,000 people and serving around 2.7 million residents. Affiliated with the University of Oslo, it combines local, regional, and national emergency services with pioneering biomedical research and education.
Core provides services, including sample analysis and cell sorting, as well as instrumentation, software, and technical expertise/advice for a variety of flow cytometric protocols. Training is available to enable users to run the cytometers themselves.
Core provides centralized administrative, operational, fiscal, regulatory, and communication support for the COBRE on Opioids and Overdose. Services include project management, pilot project administration, investigator support, grant and IRB assistance, meeting and event coordination, mentorship program administration, reporting, dissemination support, and coordination across COBRE cores and leadership.
Core provides fluorescence imaging services for HUN-REN BRC researchers, for collaborators from the SZTE and other Hungarian institutes, and for EuroBioImaging members. The available equipment consists of confocal laser scanning microscopes, fluorescence and stereo microscopes. Our expertise, image processing software collection and the available courses are supporting the efficient research.
Centralized molecular and analytical core that provides full service genomic library preparation, high-throughput DNA/RNA extractions, small molecule analysis, and routine isolation and storage of microbial strains. Specializes in environmental samples and offer low-cost fees for training and walk-in instrument use. Functions as a bio-repository of experimental arthropod models including Drosophila and other endemic insects.
Facility develops and characterizes clinically annotated patient-derived organoid and stromal cell models to support translational cancer research. Provides standardized model generation, comprehensive validation, experimental services, and investigator training to accelerate precision oncology studies
Core facility provides services including generation of new monoclonal antibodies , scaleup production , purification of antibody from existing cell lines and antibody conjugation.
Advanced confocal laser scanning microscope customized with an upright frame, specialized infrared lasers, and detectors. It allows researchers to look deep into thick, living tissues (intravital imaging) with exceptional clarity and minimal damage to the specimen.
Automated, all-in-one inverted microscope designed primarily for high-throughput live-cell imaging and 3D cell culture (like organoids). It combines the ease-of-use of an automated, boxed system with the advanced optics and flexibility of a classic research microscope.
Benchtop flow cytometer used to analyze and count individual cells or particles. Flow cytometer with 3 lasers (488, 405, 640 nm) and up 14 colors. 6 colors from violet laser; 5 colors from blue laser; 3 colors from red laser. NovoExpress software used for acquisition.
Biotech company headquartered in Castel Maggiore, Bologna, Italy, manufactures and markets health care technologies and products. Provides commercial molecular laboratory service for targeted next-generation sequencing library preparation, sequencing, and bioinformatic variant analysis of enriched circulating multiple myeloma cells, delivering an annotated report of somatic sequence and copy-number alterations.
Core provides expertise and support for biomedical research to assess and improve animal models of disease. Performs detailed characterization of animal models across species and research areas via histopathology, DNA and RNA interrogation, and spatial assessment assays.
Software cloud-optimized WDL workflow that performs cell type label transfer using scVI and scANVI (single-cell ANnotation using Variational Inference) deep generative models. It integrates single-cell RNA-seq (GEX) and, optionally, ATAC-seq data with an annotated reference dataset to transfer cell type labels via semi-supervised learning.
Biotechnology and diagnostics company specializing in "liquid biopsy" technologies to detect and isolate rare cells like circulating tumor cells (CTCs) from blood or tissue samples. They provide precise single-cell analysis tools used in cancer research and personalized medicine. Offers commercial rare-cell laboratory service providing CD138-positive immunomagnetic enrichment of plasma cells from peripheral blood and immunofluorescence-based plasma-cell identification and enumeration, delivering an enriched circulating multiple myeloma cell fraction for downstream analysis.
Facility offers sequencing services including expertise, sequencing experiment design, data analysis. Provided instruments include Illumina MiSeq and NextSeq500 sequencing platforms for low and medium throughput, which can supply single or paired reads from 75 to 600 cycles, Oxford NanoPore Technologies GridION and PromethION platforms and MinIONs. Core helped to develop software tools for MinION data analysis.
United States based educational platform dedicated to changing research culture by providing comprehensive educational materials, promoting best practices, and fostering a community committed to improving research reliability. Helps researchers learn and implement scientific rigor, such as proper experimental design, avoiding bias, and statistical analysis. Offers modules that address common issues such as experimental design, causal inference, avoiding statistical fallacies, and writing transparently reproducible code.
National, peer led consortium of institutions that advocates for systemic changes to improve research quality, training, and open science practices. It unites researchers, universities, funders, and publishers to promote open research practices, share best practices, and reform how researchers are evaluated and rewarded. Provides training resources and workshops to help researchers adopt transparent methods, such as sharing open data and code. It operates grassroots local networks at universities across the country, connecting researchers to exchange ideas and collaborate across different career stages and disciplines.
Core provides advanced instrumentation, consultation, and support for flow cytometry, light and electron microscopy, and small-animal imaging. Services include confocal microscopy, multi-plex whole slide imaging, conventional, widefield epifluorescence microscopy, Electron Microscopy, in vivo small animal PET, SPECT, CT, X-Ray, white light, fluorescence, and bioluminescence imaging, in vitro and in vivo X-Ray irradiation, multi-parameter flow cytometry, including conventional and spectral technologies, cell sorting, imaging cytometry, and advanced data analysis support.