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Software tool as open simulation environment for cardiac electrophysiology. Cardiac electrophysiology simulator for in silico experiments. Offers single cell as well as multiscale simulations from ion channel to organ level. Includes functions for pre and post processing of data as well as visualization.
Software tool as interactive explorer for single cell transcriptomics datasets. Used to explore and visualize high dimensional single cell datasets in interactive way. Can visualize gene expression at level of entire dataset or particular subset of cells to help identify cell types, which can in turn help identify diseases. Enables plotting gene expression level against another gene to compare how these different genes are expressed across dataset. Open source cell visualization tool integrates with tools like SciPy and Jupyter.
Open source software R package for assaying variation of gene set enrichment over sample population.Used for microarray and RNA-seq data analysis. Gene set enrichment method that estimates variation of pathway activity over sample population in unsupervised manner.
Open source software for zebrafish eye tracking and visual stimulation. Used to evoke and track zebrafish eye movement in multiple larvae.Modular software able to control multiple aspects of oculomotor experiment, from stimulus presentation and data acquisition to eye tracking and data analysis, or to simply track eyes in existing video of larval zebrafish. In both cases, eyes of up to six fish can be tracked in parallel.Users can choose to control several alternative setups and optional hardware.
Software tool to subset samples in FlowJo software.Reduces number of events in data matrix by generating subpopulation containing cells distributed regularly or randomly throughout selected parent population.
Software for analyzing mass cytometry (CyTOF) data.
Software package contains data analysis and processing tools required for rapid and effective interrogation of imaging data. Allows for full integration of full spectrum molecular imaging experiments on SYNAPT family platforms, as well as DESI imaging on Xevo G2-XS QTof Mass Spectrometers, using single user interface.
Software R package and ShinyApp for producing PRISMA 2020 compliant flow diagrams. ShinyApp for producing PRISMA 2020 compliant flow diagrams.
Reference dataset of multiplexed immunofluorescence microscopy images collected at HMS Laboratory of Systems Pharmacology. Includes set of images of different types for development and benchmarking of computational methods for image processing. As of 4/2/2021, EMIT comprises tissue microarray containing cores from 34 cancer, non-neoplastic diseases, and normal tissue collected from clinical discards under IRB supervised protocol. TMA was imaged using cyclic immunofluorescence method. Additional extensions of EMIT are currently in the planning stages. Long term goal is to compose ImageNet like resource for highly multiplexed images of tissues and tumors by consolidating high quality curated datasets.
Software tool as testbed for text mining methods that assess Randomized Controlled Trial transparency, rigor, and reliability, and support methods for peer review and authoring assistance.
Software tool as set of deep learning nuclei instance and semantic segmentation models that have been trained on 6 human tissue types: tonsil, small intestine, ovary, and cancers of brain, colon, prostate, and lung stained with Hoechst 33342 and combination of lamin B2 and nucleoporin98. Includes manually curated annotations as well as novel concept of introducing intentionally defocused and saturated images for robustness.
dkNET service that assist researchers in generating research hypotheses. Brings together collection of online tools that will allow researchers to explore different dataset and utilize analytics and visualization tools. Hypothesis Center phenotype-genotype analytics module is currently performed utilizing data from Signaling Pathways Project , and Mouse Metabolic Phenotyping Centers, and it brings SPP and MMPC together to connect cellular signaling pathways and gene expression with physiological phenotypes. Used to find gene sets and signaling pathways relevant to mouse phenotypes for generating hypotheses.
Open source software tool as multiple choice microscopy pipeline for multiplexed whole slide imaging and tissue microarrays. Scalable, modular image processing pipeline for multiplexed tissue imaging. Used for performing sequential steps needed to transform large, multi channel whole slide images into single cell data.
Manufactures range of high quality agonists, antagonists, inhibitors, activators, antibodies and fluorescent tools to support life science research.
Manufacturer of flexible shaft rotary power tools including specialized motors, handpieces, attachments, and accessories.
Supplier of high purity metals, alloys and polymers including Aluminium, Indium, Platinum, Silver, Gold, Copper, Indium, Iridium, Rhodium and Tantalum in multiple forms, dimensions and purities.
Images and tracks one eye of human subject or lower animal at operator selected sampling rate at 120 Hz or 240 Hz. Contains all components to record eye movements as subject views imagery presented on computer screen or other visual display device. Configured to track one eye and allows for up to approximately one to two inches of side to side or up and down head movement.
Scientific setup used for both eyeblink conditioning and prepulse inhibition of startle reflex in animals. Used to measure kinetic and frequency domain properties of conditioned and unconditioned eyelid responses in freely moving mice. Allows determination of eyelid movements in time and space while using air puff as unconditioned stimulus.
P-1000 include diagnostic testing of all puller components, built in error detection of air pressure loss or filament burnout, easy access to ramp test, measurement of jaw temperature, and access to previous pull results with heat on times for each cycle of program.Help topics are pre-loaded to assist with on-site troubleshooting and built-in glossary includes text, pictures, and diagrams explaining terms used in micropipette fabrication. Rotary dial is offered as alternative to keypad for numerical entry.
Digitizer intended for precision scientific applications.Digitizes at aggregate speed of 500 kHz. It provides sixteen multiplexed, 16-bit analog inputs and two nonmultiplexed, 16-bit analog outputs.