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Software tool as reusable computational framework, enabling simplified access to modern scalable cloud based components. Implements FAIR data principles and extends them to provide fully FAIR Evidence, including machine interpretable provenance of datasets, software and computations, as metadata for all computed results.All objects are assigned persistent IDs, including software.
Software pipeline that supports processing of multiplexed single nuclei bisulfite sequencing data to detect methylated bases. Alignment and methylated base calling pipeline that trims adaptors, attaches cell barcodes, aligns reads to genome, filters reads based on quality and creates both VCF and ALLC file with Emethylation site coverage.
Software tool for modelling RNA binding protein binding preferences. Used to predict RPB binding sites. Computational RBP binding site prediction framework based on recurrent neural networks. Includes functionalities from dataset generation over model training to evaluation of binding preferences and binding site prediction.
Behavioral two photon imaging system. Includes two photon scanning microscope, software and virtual reality set up. Used for chronic two photon imaging in mice exploring virtual environment. Tool in neuroscience to allow for chronic measurement of activity of genetically identified cells during behavior.
Open source game engine and framework for 3D rendering and game development for Python and C++ programs. Graphics engine and programming environment to support everything from real time graphics applications to development of high end virtual reality theme park attractions or video games.
Portal for cross sectional study where population based sample of adult cancer patients were recruited for mailed survey (with telephone follow-up of non-responders) to evaluate equivalence of PROMIS measures across socio-demographic and clinical sub-groups.
Data repository for Friedrich Miescher Institute for Biomedical Research in areas of epigenetics, quantitative biology, and neurobiology.
Software package for image processing for MATLAB. Used for processing of calcium imaging data.
Software LabView package for two-photon calcium imaging acquisition. Used for controlling two-photon microscope and preprocessing of calcium imaging data.
Web based portal using web based tools for analyzing real-time qPCR or next-generation sequencing data. NGS modules support analysis of QIAGEN's QIAseq NGS library kits and target enrichment panels.
Software tool to create realistic networks of neurons, synapses placed using touch detection between axons and dendrites.Used to create detailed network of connected neurons, where connectivity is derived from reconstructed neuronal morphologies as well as from more qualitative experimental knowledge. Supports creation of network with connectivity based on touch detection.
Provides short training courses to in service public health practitioners and professionals.Offers teaching, research, and policy advice in public health in Pakistan.
Matchmaking platform for clinicians and scientists to facilitate collaborative research on rare and undiagnosed diseases. Used for collaborative projects that advance scientific knowledge and patient care. Currently supports Mouse, Rat, Frog, Zebrafish, Fruit Fly, Nematode Worm, Budding Yeast, Fission Yeast, and E. coli. Used to identify human ortholog of genes in these model organisms and vice versa. Scientists who register in ModelMatcher are asked to classify their genes of interest into Public or Restricted categories.The Match feature will allow Clinicians to obtain information on genes that Scientists classify as both Public and Restricted.
Facility that provides CRISPR services and expertise to facilitate study of gene function. Services include project consultation, sgRNA design and cloning, lentivirus production, custom CRISPR cell line generation and genome wide CRISPR screen.
Hood holds any animal lab chambers while continuously sweeping all experiment related off gases away.Used to capture and exhaust gases or vapors which escape from animal chamber and directs them to safe location.Helps to control animal odor in the lab. Available in standard and customized dimensions.
Parts per million limit controller primarily used for assuring consistent and acceptable off gas levels in variety of animal enclosures.
Software tool to measure area of invading spheroid in 3D cell invasion assay. Can also count and measure area of nuclei within spheroid.
Isolator that provides physiologically relevant oxygen as well as low contamination risk cell incubation and handling. Subset of Cytocentric Platform designed for processing and producing cells in compliance with regulatory GMPs. Includes glovebox and tanked gases for atmosphere for controllable humidity and microbial risks. Modular and customizable.
Software to create and edit sample sheet in order to perform next generation sequencing on Illumina paltforms. Used for MiniSeq, MiSeq, NextSeq 500/550, HiSeq, and NovaSeq 6000 Systems.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 11, 2025. Interdisciplinary team of engineers and scientists, representing fields of physics, mathematics, and computer science, that combine their expertise in areas such as microscopy, lasers, optoelectronics, applied mathematics, image and signal processing, computer graphics, computer vision, statistics, software engineering, and biophysics, to develop imaging approaches for cell biology. Pioneers in high-resolution 3D imaging using wide-field fluorescence microscopy together with digital image deconvolution, and image visualization and quantitative analysis techniques, especially as applied to statistical analysis of images to determine co-localization of fluorescence markers inside cells.Research includes development and application of light microscopy and imaging in cell biology and biophysics.Developed TESM microscope that combines Total internal reflection fluorescence (TIRF) with Epi-fluorescence Structured illumination to provide new views of trafficking in near plasma membrane domain of cells.Provides custom-built, ultra-high-speed microscope system for imaging dynamics of intracellular calcium channel events, called calcium sparks, that are being found to regulate expanding array of cellular processes. Provides two photon fluorescence microscope for looking deep inside tissue, completing range from molecule to organism. Areas of ongoing technology research include high-speed, high-resolution imaging of live cells and tissues, novel image processing approaches, high-performance computing, and computer graphics.