We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Web tool used to batch edit Wikidata items, based on simple set of text commands. Can add and remove statements, labels, descriptions, and aliases.Can add statements with optional qualifiers and sources.
Web tool to edit property value of several items on one screen.Used to see and edit labels, descriptions, aliases, and properties for list of Wikidata items, in tabular form.
Software Python tool as Vanderbilt University curation tool.Used for exporting public profiles of university faculty from Vanderbilt University database into Wikidata.Used to create or update items in Wikidata using data from CSV spreadsheet data.
Clinical trials database.
Software tool for importing clinical trials into Wikidata.
Non-biting midge
Centralized, coordinated imaging facility.Provides electron and ion beam analytical microscopy instruments.Full service facility from extensive sample preparation laboratories to image processing tools and support.
Genomics Section provides services and instrumentation that enable DNA/RNA extraction and quality control, next-generation Illumina and Nanopore sequencing, epigenetic profiling, and microarray analysis on a whole-genome scale, from the level organisms to single cells. Molecular Biology Section provides DNA fragment analysis qPCR, Sanger sequencing and NanoString Technology.
Core offers high throughput Sanger sequencing for any number of samples with 24 hour turn around time,PCR cleanups and mini-preps as well as sample prep from colonies or pellets.Provides large plasmid repository with over 300,000 constructs.Provides ORFs from MGC, Yeast, Xenopus, Drosophila, mouse, as well as several many other organisms including bacterial species. Accept deposits.
UAF IAB Genomics Core Lab provides library preparation and sequencing services for the Illumina MiSeq sequencer, and the Oxford Nanopore Technologies GridION. For UAF researchers, we also provide training and access to specialized equipment relating to the purification, quantitation, amplification and library preparation of DNA and RNA.
Centralized, quality controlled facility and biorepository for processing, storage and disbursement of human specimens.Offers high throughput processing of human biospecimens, with specific emphasis on DNA and RNA isolation and purification.Provides laboratory support for investigator initiated large scale clinical, epidemiologic, and other studies.Functions as human specimen biorepository resource for clinicians who wish to store and study samples from unusual or potentially important patients.Biorepository is managed by custom LIMS, with sample accessioning, tracking and audits at each step.Provides scientific resource for investigators seeking advice or consultation on study design including specimen collection and storage methods, and human subject issues. Core staff act as liaison to other UNC core facilities and outside collaborators.
The MIC Live Imaging and Physiology Core is a division of the Microscopy and Imaging Center of the UVM Larner College of Medicine. The Live Imaging and Physiology Core provides a wide range of imaging techniques mainly for live-cell, live-tissue and in-vivo preparations. We maintain a Noran/Prairie Technologies OZ LSCM (laser scanning confocal microscope), a DeltaVision RT restoration microscopy system, a Zeiss/BioRad 2100 dedicated multiphoton LSCM, a Zeiss LSM 7 MP dedicated multiphoton LSCM, a Nikon TIRF (total-internal reflection fluorescence) system, a Nikon/Yokogawa CSU-W1 spinning disk microscopy system, a PTI monochromator system, and a Nikon SMZ-1500 fluorescence stereoscope. Patch-clamp electronics are available for use on most microscope systems, and each system has an integrated perfusion setup.
Provides source for characterization of biological, soft matter, and hybrid samples with TEM (Transmission Electron Microscopy), SEM (Scanning Electron Microscopy), and STEM (Scanning Transmission Electron Microscopy) at cryogenic or at ambient temperature.Provide expertise and access to equipment for cryofixation and processing of frozen hydrated samples by high pressure freezing, plunge freezing, freeze fracturing, cryo ultramicrotomy, freeze substitution, and turbo freeze-drying. Conventional samples can be processed at ambient temperature with chemical fixation, dehydration, and resin embedding, or critical point drying. Offers EDX (Energy Dispersive X-ray Spectroscopy) for elemental analysis.Offers training on instruments and sample preparation techniques.BioCryo staff mentors new users, advises on experimental design, and collaborates with researchers in experiments with challenging and unconventional samples.BioCryo Facility participates in numerous educational and outreach events, e.g. workshops, seminars, demos, and facility tours.
Provides service that maps protein DNA interactions genome wide, tracks experimental metadata, and implements quality controlled data processing and research based analysis pipelines. Provides epigenomic and bioinformatic research resources and services that include sample preparation services and data generation. Open source platforms enable and reinforce FAIR data practices. Core is able to receive and process cell and tissue samples for various diagnostic epigenetic assays.
Comprises six service groups. Our services are available to all NIH intramural researchers, and by interagency agreements to FDA and US Army at Ft. Detrick. We are happy to consult and distribute materials to not-for-profit institutions.Clone Optimization service include DNA cloning for protein expression; Gateway-based; fluorescent, epitope, solubility, purification tags; mutagenesis; vectors for insect/ baculovirus, mammalian, E. coli, P. pastoris, K. lactis. Microbial Expression: E. coli, P. pastoris, K. lactis, 2 mL to 60 L, autoinduction and IPTG; fully instrumented fermenters.Eukaryotic Expression service include insect / baculovirus, mammalian transient and stable, monoclonal antibodies.Protein Purification service include parallel microscale for process development; affinity and native, tag and endotoxin removal; scale-up to low gram scale.Virus Technology service include custom and stock adenovirus and lentivirus production; titer determination; promoter and reporter panels in lentivirus ready to deliver.Molecular Detection: qPCR and ELISA assaysdeveloped and executed, focused on human viruses in human samples; qPCR assays for mycoplasma and human pathogenic viruses contaminating cell lines; cell line identity testing.
Core provides services related to manipulation and delivery of nucleic acids to biological systems. Services include Production and titering of recombinant viral vectors,including Lentiviruses, Adenoviruses, and Adeno associated viruses;Subcloning;Tagging of open reading frames;Development of plasmids and/or RNAs for CRISPR/Cas manipulation;piggyBac transposon delivery systems;Real-time PCR analysis;Recombineering;In vitro transcription; Core maintains stock of plasmids that provide components for building constructs envisioned by investigator and provides consultative services.Provides training opportunities in the technologies described above, either as a for-credit, one semester class or on a project-related, fee-based basis.
Supports generation and utilization of genetically modified mice, design and production of genetic constructs with methods including yeast and E.coli recombineering, ES cell targeting (transfection, drug selection, and expansion). Produces transgenic mice: DNA injections into oocytes, ES cell injections into blastocysts.Provides humanized immune system mouse models.Offers start to finish experiment services to assist your many needs, please ask for more info.Other services include animal husbandry, IP and IV injections, blood drawing, necropsy and surgeries- embryo transfers, ovariectomy, vasectomy, tumor removal.
Provides instrumentation, supplies, and expertise to assist researchers in structural characterization of biological macromolecules. Resources are available for crystallization and structure determination as wells as biophysical characterization of macromolecular stability and interactions.
Web service to generate DsiRNAs for any sequence from any species by Integrated DNA Technologies.
Literature mining web service that searches all PubMed abstracts for user provided gene symbols in conjunction with set of custom keywords organized into customized ontology, as well as results from human genome wide association studies (GWAS). Searches gene symbols against list of keywords in PubMed to extract sentences that contain at least one gene and one keyword. Used to mine PubMed for gene relationships using custom ontology and deep learning.