Curator Dashboard

Software application for power and sample-size calculations for the TDT and ASP tests under a wide variety of ascertainment schemes. Uses the flexible genetic model of McGinnis. Most calculations are exact rather than asymptotic. (entry from Genetic Analysis Software)

• Resource
• SciCrunch
• 14 years ago - by Anonymous

Core facility provides neural stem cells (NSC) and everything you need to grow them, custom lentiviral shRNA and over-expression vectors, consult based characterization service where we can assess how your products or reagents affect stem cell performance and behavior. Services include:Cell Supply,Adult SVZ Neural Stem Cells,Any Age Embryonic stem cells from any region of the brain,Human Retinal Pigmented Epithelial cells,RPE iPSCs,iPSCs,Neural Progenitor Cells (NPCs),Custom Orders,Media/ Dissociation Reagents,High-performance Media formulated according to optimal cell growth conditions,Complete Defined Media for Neural Stem Cell Culture,Complete Defined Media for Human Retinal Pigmented Epithelial Culture,Cell characterization. Performs assays to verify how stem cell populations behave in response to certain environments, plastics, reagents, etc., using trade secret assays via FACS and cell culture techniques. This can be used for neural stem cells as well as embryonic stem cells.Cell banking solutions shall ensure that their integrity is maintained, and that sufficient supply is readily available. We will also expand cells, harvest cells, generation the freezing medium and thaw cells to test performance. Provides Generation of custom lentiviral shRNA constructs,Generation of custom lentiviral over-expression constructs,Supply of NSC lines already expressing these shRNA or over-expression constructs.

• Resource
• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Provides access and training on two FACS Calibur benchtop cytometers, one FACS Canto II multi-laser digital cytometer, one FACS Aria II cell sorter, one FACS Aria III cell sorter, and one Sony SH800 cell sorter. These systems are primarily used for the rapid analysis and sorting of single-cell suspensions. To analyze the light scatter and fluorescence characteristics of a cell population, one of the benchtop machines is appropriate. For more complex assays requiring more than four differentiating markers, then the high-end multi-laser Canto II system would work well. To rapidly retrieve or sort a particular sub-group of cells from a mixed sample, then a cell sorter would be required.

• Resource
• RRID
• 1 year ago - submitted by Edyta Vieth

A database-based neuron simulation tool. An innovative approach to large-scale, biologically plausible, neural-network simulation library. Based on data structures and methods directly coded into database, information flow implying separation of data representing neurons, conceived to share load on multiple machines and calibrating operational load on each machine.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

Core provides sample preparation, metal extraction, dissolved solids measurement, analytic consultation, and technical writing assistance) in support of wide range of clinical and biomedical research projects.Instruments include Agilent 5100 SVDV Inductively-Coupled Plasma-Optical Emission Spectrometer, SPS3 Robotic Autosampler,MARS5 Microwave Sample Digestion Oven,ICPExpert Advanced Workstation.Analytic Capabilities:Simultaneous, multi-element quantitation over wide dynamic range;Broad elemental detection capability with high precision and sensitivity;Compatible with range of clinical, nutritional, basic research, and pharmaceutical samples;Tolerant of high total dissolved solids and complex matrix components;NIST-traceable calibrants, standards, and other QA/QC controls included in analyses.

• Resource
• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core offers comprehensive instrumentation and technical support for all aspects of in vitro and in vivo pre-clinical non-human anatomical and molecular imaging. Studies may be conducted on samples prepared to exhibit characteristic features for a particular imaging modality. Within the intact environment, physiological and pathophysiological activity may be observed through imaging or numerous biological pathways and interactions involved in injury and disease progression, such as traumatic brain injury, cardiac disease, tumorigenesis, and therapeutic interventions.

• Resource
• SciCrunch
• 1 year ago - submitted by Edyta Vieth

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 28,2023. Platform for Neuroscientists to describe neurons and neural circuitry. Registered users may edit. The ultimate goal is advance the field of Neuromics by creating an encyclopedia of neurons and neural circuitry. NOTE: The database is no longer being maintained due to lack of funding.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

Software tool to perform intersectional genetics-related operations to find VEnCodes using databases provided by FANTOM5 consortium, namely CAGE enhancer and transcription start site (TSS) databases.

• Resource
• SciCrunch
• 7 years ago - submitted by Andre Macedo

Provides services and instrumentation including Illumina Next-Generation Sequencing, Single Cell Analysis and Spatial Transcriptomics. These techniques are developed and optimized by our lab scientists to deliver the highest-possible quality sequencing data from a wide variety of sample types such as peripheral blood, bone marrow, fresh frozen tissue and FFPE-derived tumor samples.

• Resource
• RRID
• 1 year ago - by Anonymous

A single nucleotide variant caller optimised for identifying somatic variants in low cellularity cancer samples.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Software R package for computing and annotating genomic ranges. Used for storing and manipulating genomic intervals and variables defined along genome.

• Resource
• RRID-Legacy
• 7 years ago - submitted by Anita Bandrowski

Software R package contains functions for drawing survival curves using 'ggplot2'.

• Resource
• RRID
• 1 year ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE, documented May 10, 2017. A pilot effort that has developed a centralized, web-based biospecimen locator that presents biospecimens collected and stored at participating Arizona hospitals and biospecimen banks, which are available for acquisition and use by researchers. Researchers may use this site to browse, search and request biospecimens to use in qualified studies. The development of the ABL was guided by the Arizona Biospecimen Consortium (ABC), a consortium of hospitals and medical centers in the Phoenix area, and is now being piloted by this Consortium under the direction of ABRC. You may browse by type (cells, fluid, molecular, tissue) or disease. Common data elements decided by the ABC Standards Committee, based on data elements on the National Cancer Institute''s (NCI''s) Common Biorepository Model (CBM), are displayed. These describe the minimum set of data elements that the NCI determined were most important for a researcher to see about a biospecimen. The ABL currently does not display information on whether or not clinical data is available to accompany the biospecimens. However, a requester has the ability to solicit clinical data in the request. Once a request is approved, the biospecimen provider will contact the requester to discuss the request (and the requester''s questions) before finalizing the invoice and shipment. The ABL is available to the public to browse. In order to request biospecimens from the ABL, the researcher will be required to submit the requested required information. Upon submission of the information, shipment of the requested biospecimen(s) will be dependent on the scientific and institutional review approval. Account required. Registration is open to everyone., documented on August 1, 2015. Consortium that aims to facilitate interdisciplinary collaborations to advance the understanding of pancreatic islet development and function, with the goal of developing innovative therapies to correct the loss of beta cell mass in diabetes, including cell reprogramming, regeneration and replacement. They are responsible for collaboratively generating the necessary reagents, mouse strains, antibodies, assays, protocols, technologies and validation assays that are beyond the scope of any single research effort. The scientific goals for the BCBC are to: * Use cues from pancreatic development to directly differentiate pancreatic beta cells and islets from stem / progenitor cells for use in cell-replacement therapies for diabetes, * Determine how to stimulate beta cell regeneration in the adult pancreas as a basis for improving beta cell mass in diabetic patients, * Determine how to reprogram progenitor / adult cells into pancreatic beta-cells both in-vitro and in-vivo as a mean for developing cell-replacement therapies for diabetes, and * Investigate the progression of human type-1 diabetes using patient-derived cells and tissues transplanted in humanized mouse models. Many of the BCBC investigator-initiated projects involve reagent-generating activities that will benefit the larger scientific community. The combination of programs and activities should accelerate the pace of major new discoveries and progress within the field of beta cell biology.

• Resource
• SciCrunch
• 15 years ago - by Anonymous

Web tool for display, annotation and management of phylogenetic trees. Accessible with any modern web browser.

• Resource
• RRID-Legacy
• 7 years ago - submitted by Chao Yang

Core offers recombinant protein expression and purification in E. coli systems to investigators for functional and structural studies. Services include vector construction, expression optimization, protein purification using FPLC, and isotopically labeled protein expression for NMR. Clients can choose from expression strain delivery, optimized protocols, and/or purified protein, with fast turnaround times and consultation throughout the process.

• Resource
• RRID
• 1 year ago - submitted by Mike Sabo

A blog that explores local science, nature, and environment issues & experiences in Northern California. A collaborative effort, our many writers come from local museums, zoos, science centers and research institutions, as well as KQED''s TV and Radio producers covering stories in the field.

• Resource
• SciCrunch
• 15 years ago - by Anonymous

Data and information collection and repository for biological activities of small molecules and small interfering RNAs (siRNAs) hosted by the US National Institutes of Health (NIH). Used to select and summarize the bioactivities of tested substances.

• Resource
• SciCrunch
• 16 years ago - by Anonymous

Software interface for interacting with brain atlases. Python client to brain atlas framework that integrates brain parcellations and reference spaces at different spatial scales, and connects them with broad range of multimodal regional data features. It aims to facilitate programmatic and reproducible incorporation of brain parcellations and brain region features from different sources into neuroscience workflows.

• Resource
• RRID
• 1 year ago - by Anonymous

The core mission of the AXA Research Fund is to finance basic research contributing to understand and prevent risks. We support innovative and cutting-edge projects within three areas: environmental, life, and socio-economic risks. Only research institutions may submit applications. * Funding for research projects, postdoc and graduate fellowships, and long and short term projects * Encourages international applicants and research around the world Research projects funded by the Fund must fall within the scope of one of the themes identified by the AXA Scientific Board. The themes for 2011 are identified below: * Life risks ** Aging & Long-term care ** Biomedical risks ** Addictions and risky behaviors * Socio-economic risks ** Geopolitical risks ** Macroeconomic and financial systemic risks ** Individual and collective behaviors when facing uncertainties ** Large corporate risks * Environmental risks ** Climate change ** Natural hazards ** Human driven environmental changes

• Resource
• SciCrunch
• 15 years ago - by Anonymous

Software tool to searches one or more input files for lines containing a match to a specified pattern. Prints lines that contain match for one or more patterns. Command-line utility for searching plain-text data sets for lines that match regular expression. When finds match, it copies line to standard output (by default), or produces whatever other sort of output you have requested with options.

• Resource
• RRID-Legacy
• 7 years ago - submitted by Anita Bandrowski