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Showing 20 out of 28,805 Resources on page 369

Teensy-Based Interface project

Portal provides Teensy-Based Interface system. System includes Teensy 3.2 microcontroller based interface that is easily programmable, and offers high speed, precisely timed behavioral data acquisition and digital and analog outputs for controlling sCMOS cameras and other devices. Developed by Boston University scientists.

  • Resource
  • SciCrunch
  • 5 years ago - submitted by Edyta Vieth

Moving Wall Box

Portal provides Moving Wall Box system used to testing strategy task where mouse is repeatedly forced to jump over small ice by slowly moving walls whereby presence of animal is automatically sensed via balances and analyzed by microcontroller board which in turn controls movements of walls. Device provided by Max Planck Institute of Psychiatry scientist. Used for repeated assessment of fear coping strategies.

  • Resource
  • SciCrunch
  • 5 years ago - submitted by Edyta Vieth

DIY Rodent Running Disk

Portal related to Rodent Running Disk. Provided Rodent Running Disk was developed by University of California, Berkeley scientist. Acrylic disk mounted to optical encoder to achieve fast locomotion decoding.

  • Resource
  • SciCrunch
  • 5 years ago - submitted by Edyta Vieth

Modular Automated Platform for Large Scale Experiments project

Portal related to measurement of fly social networks and behavior. Provides Drosophila handing robot that boasts modular design, allowing platform to both automate diverse phenotyping assays and aid with lab chores (e.g., collecting virgin female flies). MAPLE permits small part manipulator, USB digital camera, and fly manipulator to work simultaneously over platform of flies.

  • Resource
  • SciCrunch
  • 5 years ago - submitted by Edyta Vieth

ArControl project

Portal related to delivering stimuli and monitoring responses. Provided behavioral platform was developed by scientists from Huazhong University of Science and Technology, Wuhan, China. System uses Arduino UNO board and simple drive circuit along with stand-along GUI application. Experimental data is automatically recorded with built-in data acquisition function and entire behavioral schedule is stored within Arduino chip.

  • Resource
  • SciCrunch
  • 5 years ago - submitted by Edyta Vieth

Ratcave project

Portal provides open source, cross platform Python library that adds 3D stimulus support to all OpenGL based 2D Python stimulus libraries. Ratcave comes with resources including basic 3D object primitives and wide range of 3D light effects. Intuitive object oriented interface allows for all objects, which include meshes, lights, and cameras, can be repositioned, rotated, and scaled.

  • Resource
  • SciCrunch
  • 5 years ago - submitted by Edyta Vieth

SnackClock

Project related to feeding behavior.Provides device for dispensing pre-measured quantities of food at regular intervals throughout day. Device uses 24 hour clock movement to rotate dispenser wheel one revolution per day.

  • Resource
  • SciCrunch
  • 5 years ago - submitted by Edyta Vieth

SignalBuddy

Portal related to signal generation. Provided system was developed by Columbia University scientists. System includes signal generator for scientific applications which generates digital or true analog signals (sine waves, step functions, and pulse trains) and can be controlled with intuitive serial monitor interface.

  • Resource
  • SciCrunch
  • 5 years ago - submitted by Edyta Vieth

OpenFeeder

Project related to studying reward and feeding behavior. Provides open source automatic feeding system that can be customized for food types from seeds to pellets.System integrates plexiglass tubes, Arduino Uno, motor driver, and piezo sensor to reliably deliver accurate amounts of food, and can also be built using 3D printed parts.

  • Resource
  • SciCrunch
  • 5 years ago - submitted by Edyta Vieth

FreemoVR project

Portal related to virtual reality for freely moving animals.Provides virtual reality system set up for unrestrained animals.System developed by University of Frieburg scientists. This Virtual Reality system can be used with number of different species including mice, zebrafish, and Drosophila.

  • Resource
  • SciCrunch
  • 5 years ago - submitted by Edyta Vieth

Touchscreen Cognition

Project related to cognitive testing method for rodents.Provides touchscreen operant platform for testing learning and memory in rats and mice.Includes device chambers that can be used to measure rodent behavior.Not open source device.

  • Resource
  • SciCrunch
  • 5 years ago - submitted by Edyta Vieth

Mousebytes

Open access database for all cognitive data collected from touchscreen related tasks. Performs data comparison and interactive data visualization for any data uploaded onto the site. There are also guidelines and video tutorials available.

  • Resource
  • SciCrunch
  • 5 years ago - submitted by Edyta Vieth

ToneBox

Project related to auditory behavioral task data collection.Provided high throughput operant conditioning in mouse homecage system was developed by University of Maryland,College Park, scientists.Automated system for training up to hundreds of mice in auditory behavioral task features custom Matlab GUI running on desktop which connects to Raspberry Pi to administer auditory stimuli from USB soundcard and collects auditory data as well as licking data from water spout with commercially available capacitive sensors. Parts list and build instructions are readily available from paper and associated GitHub repository.

  • Resource
  • SciCrunch
  • 5 years ago - submitted by Edyta Vieth

3DOC

Project related to animals learned perform action in order to achieve reward. Fully 3D printable chamber able to perform operant conditioning using off-the-shelf, low-cost optical and electronic components, that can be reproduced rigorously in any laboratory equipped with 3D printer.

  • Resource
  • SciCrunch
  • 5 years ago - submitted by Edyta Vieth

ACRoBaT

Project related to studying motor behavior. University of Washington in Seattle scientists have developed and published their device for training rats to perform modified center out task.

  • Resource
  • SciCrunch
  • 5 years ago - submitted by Edyta Vieth

Visual stimulator with customizable light spectra

Project related to visual neuroscience.Provides spatial visual stimulator with arbitrary spectrum of light for visual neuroscientists.Open source, low cost visual stimulator which can be customized with up to 6 chromatic channels. Spectrum of light can be arbitrary and customizable to be adapted to different animal models based on their visual spectrum. Device details, including parts list and information for custom python library for generating visual stimuli (QDSpy), can be found in eLife publication.

  • Resource
  • SciCrunch
  • 5 years ago - submitted by Edyta Vieth

Mitochondrial Neuron Ubiquitin

Shiny app for quick selection of ubiquitylation sites and proteins from diGly analysis of neurons stimulated with mitochondrial depolarisation.Used to visualise mitochondrial ubiquitin sites in neurons and search for ubiquitin components recruited to mitochondria upon mitochondrial depolarisation.


Chemical Probes Portal

Portal to find and use small molecule reagents called chemical probes in biomedical research and drug discovery. Molecules are evaluated by recognized chemical probe experts (Scientific Expert Review Panel, SERP) and recommendations are provided how to best use these tools.Portal includes range of chemical tools, including small molecule inhibitors, agonists, PROTACs (proteolysis targeting chimeras) molecular glues, and molecular glue degraders.Portal also curates list of historical compounds, which have been used as inhibitors in the past but are no longer considered probes.

  • Resource
  • dkNET
  • 5 years ago - submitted by Ko-Wei Lin

STARsolo

Software tool for accurate, fast and versatile mapping/quantification of single cell and single nucleus RNA-seq data. Used for mapping, demultiplexing and quantification for single cell RNA-seq. Comprehensive turnkey solution for quantifying gene expression in single-cell/nucleus RNA-seq data, built into RNA-seq aligner STAR.


Single Cell Doublet Scoring

Software R package for computational doublet annotation of single cell RNA sequencing data. Software tool for in silico identification of doublets in scRNA-seq data.