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Project to build and use new generation of home cages with emphasis on training for simple headfixed tasks during simultaneous autonomous acquisition of mesoscale brain imaging data. Homecage platform for automated task training and mesoscale brain imaging for mice developed by University of British Columbia scientists.
Portal provides system capable of frame differencing, color tracking, marker tracking, face detection, eye tracking, person detection (with TensorFlow Lite), and more. Supports very easy to use GUI, the OpenMV IDE.
Portal provides open source circuit for microwire tetrode gold plating. Circuit includes impedance meter and current generator for tetrode gold plating. Developed by University of Toyama scientist.
Portal provides miniscope for fluorescence imaging and optogenetic stimulation. Used for monitoring of neural signals during unrestrained behavior.
Portal provides open source, low cost, programmable pulse train generator for physiology and behavior. Device allows users to create and trigger software defined trains of voltage pulses with high temporal precision. Arduino powered device that generates precise sequences of voltage pulses for neural stimulation and stimulus control. Controlled either through its APIs in MATLAB, Python and C plus plus, or as stand-alone instrument using its oLED screen and clickable thumb joystick.
Portal provides open hardware used in labs for administering picoliters of liquid to biological samples. Pressure ejection system developed by University of Sussex scientist for reliably delivering picolitre volumes.
Portal provides system that combines open source hardware and software for control of behavioral experiments. Open source framework, combines Python scripts and Micropython microcontroller. Framework can be run through command line interface, or in user friendly graphical user interface that allows users to manage variety of devices such as nose pokes, LED drivers, stepper motor controllers and more. Data collected using this system can then be imported into Python for data analysis.
Portal provides computer numerical controlled robot for cranial microsurgeries developed by University of Minnesota scientist. Included cranial microsurgery platform combines automated skull surface profiling with computer numerical controlled milling machine to perform variety of cranial microsurgical procedures on mice.
Portal provides brain implant developed by MIT scientists. Implant carries 16 movable tetrodes along with two optic fibers or two injection cannulas. Designed with help of 3D CAD software, allowing modifications for various experimental needs, such as targeting different brain regions and use in other animal species (e.g., rats and non-human primates). Implant can be designed to shape of skull of individual monkeys based on pre-implantation magnetic resonance imaging, thus optimizing fit with skull surface and making recording from deep brain regions more reliable.
Portal provides open source control system for in vivo fluorescence measurements from deep brain structures developed by University of California, San Francisco scientists. Microcontroller based solution for controlling optical components in intracranial photometry system and processing resulting signal.
Portal provides low cost, open source, wireless probe for optogenetic stimulation. This wireless system for optogenetic stimulation was developed by UCLA scientists. Device consists of two parts. Optical component is mounted on head permanently, whereas electronic component is removable and is applied for each experiment. Device is controlled via custom GUI (built with the TkInter Python 2.7 library) which sends pulses to device via Arduino Uno.
Portal provides Python based camera software GUI developed by Harvard University scientists. Open source software package that allows video to be recorded in sync with behavior. Python API to record video system timestamps from Imaging Source USB cameras.
Portal provides arduino based, 3D-printed nose poke device for rats. Includes set of instructions on how to build this device using arduino, some 3D printed parts and some off-the-shelf electronic components.
Portal provides automated system for mesoscopic functional imaging that allows subjects to self initiate head fixation and imaging within home cage. Developed by University of British Columbia scientists. System for automated head fixation within mouse home cages.
Open source syringe pump apparatus developed by scientists from Michigan Technological University. Syringe pump is designed using freely available open source computer aided design (CAD) software and manufactured using open source RepRap 3-D printer and readily available parts.
Portal for open source operant chamber, based on Arduino microcontroller platform, that can be used to train mice to respond for reward. Designed by NIDDK scientists.Apparatus contains two nose pokes, drinking well, and solenoid controlled sucrose delivery system. Chamber can run magazine training, fixed ratio and progressive ratio training schedules, and can be programmed to run more complicated behavioral paradigms.
Portal provides operant box designed to train small primates in auditory tasks.Device is based on computer and Arduino Mega 2560 board, named OBAT (Operant Box for Auditory Tasks), designed to present two different auditory stimuli to small primates.All schematics and software source code are available.
Portal provides open source and affordable microscope experimental setup device based on Raspberry Pi, Arduino microcontroller and off-the-shelf electronic components. System design is based on 3D-printed mainframe, Raspberry Pi computer, and high definition camera system as well as Arduino based optical and thermal control circuits. All functions of FlyPi can be controlled through custom written graphical user interface.
Portal related to individualized tracking of self directed motor learning in group housed mice performing skilled lever positioning task in home cage. Provides system for fully autonomous training of group housed mice on forelimb motor task. Task is run and controlled by Raspberry Pi microcomputer, which allows for cages to be monitored remotely through active internet connection. System was developed by University of Ottawa scientists.
Portal provides head fixed behavioral environment that uses lightweight physical maze floating on air table that moves around animals body under direct control of animal itself.