Curator Dashboard

Collaboration between research institutes working to provide framework of regulatory genomic elements in individuals with neuropsychiatric disorders.Collaboration has resulted in comprehensive set of manuscripts published in Science providing new insights into biology of developing, adult, and diseased human brain.Manuscripts are organized around three flagship articles, first analyzing human development, second studying disease transcriptomes, and third integrating tissue and single cell data with deep learning approaches.

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• RRID-Legacy
• 5 years ago - submitted by Edyta Vieth

Center for research infrastructure combining genetic engineering capabilities, advanced phenotyping and imaging modalities, specific pathogen free animal housing and husbandry, cryopreservation and archiving at BIOCEV campus. Center aims to analyze effect of loss of function gene mutations in mice with goal to produce catalog of gene function, that will help identify causative factors of human diseases as well as novel targets for therapeutic intervention. Through adoption of standardized procedures and pipelines, and usage of quality control measures and cross validation, shared goal is to produce high quality data. Center has phenotyping capabilities to accommodate both mouse and rat disease models.

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• RRID-Legacy
• 5 years ago - submitted by Edyta Vieth

Core is comprised of Materials and Molecular Analysis (MMA), Imaging and Surface Science (ISS), and Bioanalysis and Omics (BIO) centers. MMA provides instrument capabilities and expertise in spectroscopic (optical, NMR, EPR), mass spectrometry, X-ray and materials (magnetic, thermal, physical) characterization of synthetic, environmental and biological materials, both at bulk and molecular scales; BIO provides analysis of complex biological samples using modern mass spectrometry based metabolomics and proteomics approaches, including supporting cheminformatics; ISS provides analysis of complex biological and inorganic samples using near and far field imaging methods, spectroscopy, and other surface analyses.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth

Facility provides access to high performance computing environment, BioHPC, which includes both hosted hardware and shared machines. Provides consulting and collaborations for Bioinformatics analysis and workflows.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth

Provides light microscopy and flow cytometry equipment and services for ultra structural analysis of variety of sample types. Offers assisted use and training on its instrumentation and consultations on related research. Provides access to both standard and high-end imaging instrumentation to all levels of users.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth

Biomolecular facility equipped with JEOL 120kV and Glacios 200 kV with K2 Summit direct detector. Provides insights and high throughput data collection and analysis,single particle analysis, sample screening, and high resolution reconstruction., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth

Electrophysiology core facility that is part of Ion Channels and Transporters in Immunity Research Program.Research area includes ion channel and transporter function and ionic signaling in immune cells.Users who are studying other cell types or organ systems are welcome.Provides assistance with experimental design, training, implementation, and data analysis.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth

Core offers optical analysis instrumentation from specialized light microscopes to bioluminescence preclinical imagers to flow cytometers for multicolor cellular analysis. Services include high resolution optical sectioning of fixed cells and tissues, time lapse imaging of living cell cultures, non invasive monitoring of tumor formation in preclinical studies, and extracting specific cells of interest from tissue samples.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth

Set of automated workflows for common sequencing based (Illumina) protocols, such as RNA-seq, ChIP-seq, ATAC-seq, WGBS/RRBS methylation, whole genome/exome/targeted variant detection, and contaminant screening. Sequencing data analysis pipelines.

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• SciCrunch
• 5 years ago - by Anonymous

Aesthesiometer for mechanical stimulation Model 37550. Instrument designed to automate assessment of touch sensitivity on plantar surface of rats or mice and comes ready with all necessary accessories. At each paw withdrawal, automatically detects and records latency time, and actual force at time of paw withdrawal reflex. Movable force actuator is positioned below plantar surface of animal and desired force and force speed is applied, as preset by operator. Von Frey type 0.5mm rigid filament exerts increasing force, until animal twitches its paw.

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• RRID-Legacy
• 5 years ago - submitted by Anita Bandrowski

Project to align physical sample identifiers. Used to design, develop, and promote service infrastructure to uniquely, consistently, and conveniently identify material samples, record metadata about them, and persistently link them to other samples and derived digital content, including images, data, and publications.

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• RRID-Legacy
• 5 years ago - submitted by Anita Bandrowski

Integrated platform for designing clinical trials.

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• dkNET
• 5 years ago - submitted by Maryann Martone

Software application for annotating character matrix files with ontology terms. Character states can be annotated using Entity-Quality syntax, where entity, quality, and possibly related entities are drawn from requisite ontologies. In addition, taxa (the rows of a character matrix) can be annotated with identifiers from taxonomy ontology. Phenex saves ontology annotations alongside original free text character matrix data using new NeXML format standard for evolutionary data.

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• dkNET
• 5 years ago - submitted by Maryann Martone

Platform for multilevel and longitudinal data.Provide researchers such as behavioral and social scientists with tools and education related to study design including Calculating power and sample size for any univariate or multivariate test for general linear multivariate model, assuming fixed predictors;Producing confidence intervals on power estimates for designs with fixed predictors;Producing power calculations for designs with single Gaussian covariate;Supporting designs with unequal group sizes, and complicated covariance structures;Creating basic power curves.

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• dkNET
• 5 years ago - submitted by Ko-Wei Lin

Software R package provides alternative canonical correlation,redundancy analysis function, with associated print, plot, and summary methods.

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• RRID-Legacy
• 5 years ago - by Anonymous

Software R package for significance tests for canonical correlation analysis, including asymptotic tests and Monte Carlo method.

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• RRID-Legacy
• 5 years ago - by Anonymous

Software R package for multivariate analysis and scale construction using factor analysis, principal component analysis, cluster analysis and reliability analysis.Procedures for Psychological, Psychometric, and Personality Research. Used for personality, psychometric theory and experimental psychology.

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• RRID-Legacy
• 5 years ago - by Anonymous

Facility provides diverse range of Mass Spectrometry based proteomics and metabolomics services.Services include sample preparation, sample analysis, and data interpretation.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth

Core laboratory with infrastructure and expertise to perform all aspects of protein and small molecule structure determination using X-ray crystallography. For protein structure determination, high-throughput methods are utilized to move projects rapidly from gene-to-structure.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth

Facility provides instrumentation and training in following areas of High resolution X-ray CT,Small animal X-ray CT,Flow cytometry and sorting,Confocal microscopy,Multiphoton microscopy,Super resolution microscopy,Laser capture microdissection,Light microscopy,Spectrofluorometry,Bioluminescence imaging,High resolution ultrasound imaging,Image visualization and analysis.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth